Abstract
Diabetic retinopathy (DR) is the leading cause of blindness amongst the working-age population, and diabetes accelerated cardiovascular disease (CVD) the commonest cause of death in diabetic patients. Although, there is evidence suggesting a close association between DR and CVD, particularly in patients with Type 2 diabetes, the pathophysiology underlying the link is unclear. Here we review common risk factors and pathogenic mechanisms linking DR and CVD, and aim to highlight the need for a more holistic view of the management of diabetes and its complications. The understanding of the link between the two complications could eventually lead to refined management strategies and improved patient outcomes in the expanding diabetes epidemic.
Keywords: Diabetes, Diabetic retinopathy, Diabetes accelerated cardiovascular diseases, Common pathological pathways, Therapeutics, CVD, Atherosclerosis, pathogenic mechanisms, holistic view, diabetes epidemic.
Current Diabetes Reviews
Title:Diabetic Retinopathy and Atherosclerosis: is there a Link?
Volume: 9 Issue: 2
Author(s): Thomas Phillip Ellis, Ruhul Hassan Choudhury, Kirti Kaul, Mohit Chopra, Eva Maria Kohner, Joanna Mary Tarr and Rakesh Chibber
Affiliation:
Keywords: Diabetes, Diabetic retinopathy, Diabetes accelerated cardiovascular diseases, Common pathological pathways, Therapeutics, CVD, Atherosclerosis, pathogenic mechanisms, holistic view, diabetes epidemic.
Abstract: Diabetic retinopathy (DR) is the leading cause of blindness amongst the working-age population, and diabetes accelerated cardiovascular disease (CVD) the commonest cause of death in diabetic patients. Although, there is evidence suggesting a close association between DR and CVD, particularly in patients with Type 2 diabetes, the pathophysiology underlying the link is unclear. Here we review common risk factors and pathogenic mechanisms linking DR and CVD, and aim to highlight the need for a more holistic view of the management of diabetes and its complications. The understanding of the link between the two complications could eventually lead to refined management strategies and improved patient outcomes in the expanding diabetes epidemic.
Export Options
About this article
Cite this article as:
Ellis Phillip Thomas, Choudhury Hassan Ruhul, Kaul Kirti, Chopra Mohit, Kohner Maria Eva, Tarr Mary Joanna and Chibber Rakesh, Diabetic Retinopathy and Atherosclerosis: is there a Link?, Current Diabetes Reviews 2013; 9 (2) . https://dx.doi.org/10.2174/1573399811309020006
DOI https://dx.doi.org/10.2174/1573399811309020006 |
Print ISSN 1573-3998 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-6417 |
- Author Guidelines
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers
- Announcements
Related Articles
-
Pharmacy and Exercise as Complimentary Partners for Successful Cardiovascular
Ageing
Current Vascular Pharmacology Multiple Sclerosis: Current and Future Treatment Options
Endocrine, Metabolic & Immune Disorders - Drug Targets Emerging Molecular Targets for Treatment of Erectile Dysfunction: Vascular and Regenerative Therapies on the Horizon
Current Drug Targets MicroRNAs in Cardiovascular Therapeutics
Current Topics in Medicinal Chemistry Adrenomedullin: Roles for Structure and Function in Cardiac or Vascular Tissues
Current Hypertension Reviews Recent Patents and Advances in the Next-Generation Sequencing Technologies
Recent Patents on Biomedical Engineering (Discontinued) Modulation of Cardiovascular Remodeling with Statins: Fact or Fiction?
Current Vascular Pharmacology Cardioprotective Effects of Indian Gooseberry (Emblica officinalis Gaertn) and its Phytochemicals: A Review
Current Nutrition & Food Science The Clinical Problems of Hypertension Treatment in Hemodialysis Patients
Current Vascular Pharmacology CYLD-Mediated Signaling and Diseases
Current Drug Targets The Role of Amino Acids in the Modulation of Cardiac Metabolism During Ischemia and Heart Failure
Current Pharmaceutical Design Adverse Cardiovascular Effects of Antirheumatic Drugs: Implications for Clinical Practice and Research
Current Pharmaceutical Design Update on the Evaluation and Management of Brief Resolved Unexplained Events (Previously Apparent Life-Threatening Events)
Reviews on Recent Clinical Trials The Spatial QRS-T Angle: Implications in Clinical Practice
Current Cardiology Reviews Updates on HCN Channels in the Heart: Function, Dysfunction and Pharmacology
Current Drug Targets Fetuin-A: A Multifunctional Protein
Recent Patents on Endocrine, Metabolic & Immune Drug Discovery Co-formulation of P-glycoprotein Substrate and Inhibitor in Nanocarriers: An Emerging Strategy for Cancer Chemotherapy
Current Cancer Drug Targets Strategies on the Development of Small Molecule Anticancer Drugs for Targeted Therapy
Mini-Reviews in Medicinal Chemistry Adiponectin: Merely a Bystander or the Missing Link to Cardiovascular Disease?
Current Topics in Medicinal Chemistry Gene Therapy in Liver Diseases: State-of-the-Art and Future Perspectives
Current Gene Therapy