Abstract
Benzimidazole ring system is found in many bioactive heterocyclic compounds because of their diverse biological and clinical applications. Furthermore, benzimidazole derivatives are structural isosters of naturally occurring nucleotides, thus they can interact with biological macromolecules such as proteins, enzymes and receptors. This review discusses the benzimidazole derivatives which possess anticancer activity of medicinal efficacy.
Keywords: Substituted Benzimidazoles, anticancer activity
Mini-Reviews in Medicinal Chemistry
Title:Benzimidazole Derivatives as Potential Anticancer Agents
Volume: 13 Issue: 3
Author(s): Ahmed A. El Rashedy and Hassan Y. Aboul-Enein
Affiliation:
Keywords: Substituted Benzimidazoles, anticancer activity
Abstract: Benzimidazole ring system is found in many bioactive heterocyclic compounds because of their diverse biological and clinical applications. Furthermore, benzimidazole derivatives are structural isosters of naturally occurring nucleotides, thus they can interact with biological macromolecules such as proteins, enzymes and receptors. This review discusses the benzimidazole derivatives which possess anticancer activity of medicinal efficacy.
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Cite this article as:
A. El Rashedy Ahmed and Y. Aboul-Enein Hassan, Benzimidazole Derivatives as Potential Anticancer Agents, Mini-Reviews in Medicinal Chemistry 2013; 13 (3) . https://dx.doi.org/10.2174/1389557511313030008
DOI https://dx.doi.org/10.2174/1389557511313030008 |
Print ISSN 1389-5575 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5607 |
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