Abstract
The legacy of the advances made in high-throughput screening (HTS) in the 1990's is a large source of public data from which models can be derived using QSAR methods. This paper will examine the integrity of these public data sources and the implications for model building.
Keywords: QSAR, high throughput screenings, drug discovery, error analysis, public databases
Current Topics in Medicinal Chemistry
Title:QSARs, Data and Error in the Modern Age of Drug Discovery
Volume: 12 Issue: 17
Author(s): Christian Kramer and Richard Lewis
Affiliation:
Keywords: QSAR, high throughput screenings, drug discovery, error analysis, public databases
Abstract: The legacy of the advances made in high-throughput screening (HTS) in the 1990's is a large source of public data from which models can be derived using QSAR methods. This paper will examine the integrity of these public data sources and the implications for model building.
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Cite this article as:
Kramer Christian and Lewis Richard, QSARs, Data and Error in the Modern Age of Drug Discovery, Current Topics in Medicinal Chemistry 2012; 12 (17) . https://dx.doi.org/10.2174/156802612804547380
DOI https://dx.doi.org/10.2174/156802612804547380 |
Print ISSN 1568-0266 |
Publisher Name Bentham Science Publisher |
Online ISSN 1873-4294 |
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