Abstract
The presence of DNA and RNA circulating in human plasma and serum is described. The possible sources of the DNA/RNA in blood, their ability to enter other cells and to express in the recipient cells are discussed and the relationship with metastases considered. The possible role(s) of the DNA/RNA in clinical diagnosis, in monitoring treatment and in prognosis are considered for diabetes and oncology.
Keywords: Circulating DNA/RNA, plasma/serum, diabetes, cancer, diagnosis, nucleic acid uptake/expression, recipient cells, human plasma, human blood, severe sepsis, clinical patients, systemic lupus erythematosus patients, cancer patients, tumour cell derived, cardiovascular disease
Infectious Disorders - Drug Targets
Title:Biology of Circulating Nucleic Acids and Possible Roles in Diagnosis and Treatment in Diabetes and Cancer
Volume: 12 Issue: 5
Author(s): Peter B. Gahan
Affiliation:
Keywords: Circulating DNA/RNA, plasma/serum, diabetes, cancer, diagnosis, nucleic acid uptake/expression, recipient cells, human plasma, human blood, severe sepsis, clinical patients, systemic lupus erythematosus patients, cancer patients, tumour cell derived, cardiovascular disease
Abstract: The presence of DNA and RNA circulating in human plasma and serum is described. The possible sources of the DNA/RNA in blood, their ability to enter other cells and to express in the recipient cells are discussed and the relationship with metastases considered. The possible role(s) of the DNA/RNA in clinical diagnosis, in monitoring treatment and in prognosis are considered for diabetes and oncology.
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Cite this article as:
B. Gahan Peter, Biology of Circulating Nucleic Acids and Possible Roles in Diagnosis and Treatment in Diabetes and Cancer, Infectious Disorders - Drug Targets 2012; 12 (5) . https://dx.doi.org/10.2174/187152612804142224
DOI https://dx.doi.org/10.2174/187152612804142224 |
Print ISSN 1871-5265 |
Publisher Name Bentham Science Publisher |
Online ISSN 2212-3989 |
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