Abstract
Asthma is a heterogeneous disorder with a variable course. It begins very early in life and of different phenotypes. Mainstay treatment for asthma is corticosteroids as controller therapy and guidelines recommends the add-on and step-up or step-down strategies. This review will focus on the studies that enhanced our understandings of the effects of inhaled corticosteroids on the natural course of asthma in regard to symptoms control, protective effect on lung function and potential side effects encountered during the treatment. Studies that evaluated approaches on steroid sparing effects and the effect of asthma progression in children are also reviewed.
Keywords: Asthma, children, inhaled corticosteroids, rhinitis, specific immunotherapy
Anti-Inflammatory & Anti-Allergy Agents in Medicinal Chemistry
Title:Impact of Inhaled Corticosteroids on the Natural History of Asthma in Children
Volume: 11 Issue: 3
Author(s): Aarif O. Eifan
Affiliation:
Keywords: Asthma, children, inhaled corticosteroids, rhinitis, specific immunotherapy
Abstract: Asthma is a heterogeneous disorder with a variable course. It begins very early in life and of different phenotypes. Mainstay treatment for asthma is corticosteroids as controller therapy and guidelines recommends the add-on and step-up or step-down strategies. This review will focus on the studies that enhanced our understandings of the effects of inhaled corticosteroids on the natural course of asthma in regard to symptoms control, protective effect on lung function and potential side effects encountered during the treatment. Studies that evaluated approaches on steroid sparing effects and the effect of asthma progression in children are also reviewed.
Export Options
About this article
Cite this article as:
O. Eifan Aarif, Impact of Inhaled Corticosteroids on the Natural History of Asthma in Children, Anti-Inflammatory & Anti-Allergy Agents in Medicinal Chemistry 2012; 11 (3) . https://dx.doi.org/10.2174/1871523011202030200
DOI https://dx.doi.org/10.2174/1871523011202030200 |
Print ISSN 1871-5230 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-614X |
- Author Guidelines
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers
Related Articles
-
GABAB Receptors as Potential Therapeutic Targets
Current Drug Targets - CNS & Neurological Disorders Bicyclic 6 + 6 Systems: Advances in the Chemistry of Heterocyclic Compounds Incorporated Pyrimido[1,2-a]Pyrimidine Skeleton
Mini-Reviews in Organic Chemistry Update on the Cardiac Safety of Moxifloxacin
Current Drug Safety Direct Selection of cDNAs from Filamentous Phage Surface Display Libraries: Potential and Limitations
Current Pharmaceutical Biotechnology Homogeneous Time Resolved Fluorescence Assay to Measure Histamine Release
Combinatorial Chemistry & High Throughput Screening Better Targeting Melanoma: Options Beyond Surgery and Conventional Chemotherapy
Recent Patents on Endocrine, Metabolic & Immune Drug Discovery Macrolides Allergy
Current Pharmaceutical Design Association of Genetic Polymorphisms of CYP2C9 and VKORC1 with Bleeding Following Warfarin: A Case-Control Study
Current Clinical Pharmacology Utilization of Evidence-Based Secondary Prevention Medications at the Time of Discharge in Patients with Acute Coronary Syndrome (ACS) in Qatar
Current Vascular Pharmacology Population Based Helicobacter pylori Screening and Eradication: Advances Versus Side Effects
Current Pharmaceutical Design Receptor-based 3D-QSAR in Drug Design: Methods and Applications in Kinase Studies
Current Topics in Medicinal Chemistry Effects of Sublingual Immunotherapy on Allergic Inflammation
Inflammation & Allergy - Drug Targets (Discontinued) Influence of ABCB1 Gene Polymorphisms and P-Glycoprotein Activity on Cyclosporine Pharmacokinetics in Peripheral Blood Mononuclear Cells in Healthy Volunteers
Drug Metabolism Letters Biologics for ANCA-Associated Vasculitis
Inflammation & Allergy - Drug Targets (Discontinued) Facing the threat of Antifungal Resistance: Report from the 7th Trends in Medical Mycology (TIMM-7) 9-12 October 2015, Lisbon, Portugal
Anti-Infective Agents Animal Models of Pulmonary Emphysema
Current Drug Targets - Inflammation & Allergy Policy and Adolescent Tobacco Use Prevention
Adolescent Psychiatry Substance P: Structure, Function, and Therapeutics
Current Topics in Medicinal Chemistry Patents on Immunotoxins and Chimeric Toxins for the Treatment of Cancer
Recent Patents on Drug Delivery & Formulation The Protein Profile of Fibroblasts: The Role of Proteomics
Current Proteomics