Expeditious Microwave-Assisted Synthesis of Functionalized Oxaphosphaphenanthrenes and Chromenes via Multicomponent Reactions of Trivalent Phosphorus Nucleophiles

Title:Expeditious Microwave-Assisted Synthesis of Functionalized Oxaphosphaphenanthrenes and Chromenes via Multicomponent Reactions of Trivalent Phosphorus Nucleophiles

Volume: 15 Issue: 10

Author(s): Zinatossadat Hossaini, Faramarz Rostami-Charati and Seyedeh Fereshteh Hayerizadeh

Affiliation:

Keywords: 4-hydroxycoumarine, acetylenic compounds, chromenes, one-pot reactions, trimethyl phosphate, triphenyl phosphite.

Abstract: Stable derivatives of oxaphosphaphenanthrenes were prepared by using the reactions of dialkyl acetylenedicarboxylate with 3-bromo-2-naphthol in the presence of trimethyl or triphenyl phosphite under microwave conditions at 70 °C in good yields. Under similar conditions, chromene derivatives were produced by using triethyl phosphite and dialkyl acetylenedicarboxylate in the presence of OH-acids in excellent yields

Cite this article as:

Hossaini Zinatossadat, Rostami-Charati Faramarz and Fereshteh Hayerizadeh Seyedeh, Expeditious Microwave-Assisted Synthesis of Functionalized Oxaphosphaphenanthrenes and Chromenes via Multicomponent Reactions of Trivalent Phosphorus Nucleophiles, Combinatorial Chemistry & High Throughput Screening 2012; 15 (10) . https://dx.doi.org/10.2174/138620712803901117