Abstract
The cornerstone of treating patients with shock remains as it has for decades, intravenous fluids. Surprisingly, dosing intravenous fluid during resuscitation of shock remains largely empirical. Recent data suggests that early aggressive resuscitation of critically ill patients may limit and/or reverse tissue hypoxia, progression to organ failure and improve outcome. However, overzealous fluid resuscitation has been associated with increased complications, increased length of intensive care unit (ICU) and hospital stay and increased mortality. This review focuses on methods to assess fluid responsiveness and the application of these methods for goal directed fluid therapy in critically ill and peri-operative patients.
Keywords: Hemodynamic monitoring, volume responsive, fluid challenge, bioreactance, passive leg raising
Current Pharmaceutical Design
Title:Goal Directed Fluid Therapy
Volume: 18 Issue: 38
Author(s): Paul E. Marik and Himanshu Desai
Affiliation:
Keywords: Hemodynamic monitoring, volume responsive, fluid challenge, bioreactance, passive leg raising
Abstract: The cornerstone of treating patients with shock remains as it has for decades, intravenous fluids. Surprisingly, dosing intravenous fluid during resuscitation of shock remains largely empirical. Recent data suggests that early aggressive resuscitation of critically ill patients may limit and/or reverse tissue hypoxia, progression to organ failure and improve outcome. However, overzealous fluid resuscitation has been associated with increased complications, increased length of intensive care unit (ICU) and hospital stay and increased mortality. This review focuses on methods to assess fluid responsiveness and the application of these methods for goal directed fluid therapy in critically ill and peri-operative patients.
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Cite this article as:
E. Marik Paul and Desai Himanshu, Goal Directed Fluid Therapy, Current Pharmaceutical Design 2012; 18 (38) . https://dx.doi.org/10.2174/138161212803832399
DOI https://dx.doi.org/10.2174/138161212803832399 |
Print ISSN 1381-6128 |
Publisher Name Bentham Science Publisher |
Online ISSN 1873-4286 |
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