Expedient and Green Synthesis of Some Novel 4-Thiazolidinones and New 2,4-Disubstituted Thiazoles with Tetrahydro Carbazole Pendant

Title:Expedient and Green Synthesis of Some Novel 4-Thiazolidinones and New 2,4-Disubstituted Thiazoles with Tetrahydro Carbazole Pendant

Volume: 9 Issue: 9

Author(s): Deepika Gautam, Poonam Gautam and Ram P. Chaudhary

Affiliation:

Keywords: 4-Thiazolidinones, N-methylpyridinium tosylate, cyclocondensation, thiazoles, grinding, heterocyclic carbazole motif, optoelectronic devices, quantitative, internal standard, chromatography

Abstract: A green and efficient synthesis of novel 4-thiazolidinones 4 from cyclocondensation reaction of 2-(2,3-dihydro- 1H-carbazol-4(9H)-ylidene)hydrazinecarbothioamide 3 and α-haloacids catalyzed by N-methylpyridinium tosylate in quantitative yield is reported. Also, synthesis of new 2,4-disubstituted thiazoles 5 under grinding conditions is reported.

Cite this article as:

Gautam Deepika, Gautam Poonam and P. Chaudhary Ram, Expedient and Green Synthesis of Some Novel 4-Thiazolidinones and New 2,4-Disubstituted Thiazoles with Tetrahydro Carbazole Pendant, Letters in Organic Chemistry 2012; 9 (9) . https://dx.doi.org/10.2174/157017812803521081