Abstract
Photodynamic therapy (PDT) is a promising approach to treat certain types of cancer. PDT was proposed as a useful oncology tool more than 30 years ago but it has limitations. The success of PDT depends predominantly on photosensitizers and development of an effective second generation is continuing. Dendrimers possess architecture suitable for incorporating specific functional moieties and are a promising venue for further investigations. This review describes the use of dendrimers in PDT and how they can aid in overcoming obstacles encountered during PDT.
Keywords: Dendrimer, photodynamic therapy, PDT, photosensitizer, carrier, cancer, tumor
Current Medicinal Chemistry
Title:Dendrimers in Photodynamic Therapy
Volume: 19 Issue: 29
Author(s): B. Klajnert, M. Rozanek and M. Bryszewska
Affiliation:
Keywords: Dendrimer, photodynamic therapy, PDT, photosensitizer, carrier, cancer, tumor
Abstract: Photodynamic therapy (PDT) is a promising approach to treat certain types of cancer. PDT was proposed as a useful oncology tool more than 30 years ago but it has limitations. The success of PDT depends predominantly on photosensitizers and development of an effective second generation is continuing. Dendrimers possess architecture suitable for incorporating specific functional moieties and are a promising venue for further investigations. This review describes the use of dendrimers in PDT and how they can aid in overcoming obstacles encountered during PDT.
Export Options
About this article
Cite this article as:
Klajnert B., Rozanek M. and Bryszewska M., Dendrimers in Photodynamic Therapy, Current Medicinal Chemistry 2012; 19 (29) . https://dx.doi.org/10.2174/0929867311209024903
DOI https://dx.doi.org/10.2174/0929867311209024903 |
Print ISSN 0929-8673 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-533X |
Call for Papers in Thematic Issues
Advances in Medicinal Chemistry: From Cancer to Chronic Diseases.
The broad spectrum of the issue will provide a comprehensive overview of emerging trends, novel therapeutic interventions, and translational insights that impact modern medicine. The primary focus will be diseases of global concern, including cancer, chronic pain, metabolic disorders, and autoimmune conditions, providing a broad overview of the advancements in ...read more
Cellular and Molecular Mechanisms of Non-Infectious Inflammatory Diseases: Focus on Clinical Implications
The Special Issue covers the results of the studies on cellular and molecular mechanisms of non-infectious inflammatory diseases, in particular, autoimmune rheumatic diseases, atherosclerotic cardiovascular disease and other age-related disorders such as type II diabetes, cancer, neurodegenerative disorders, etc. Review and research articles as well as methodology papers that summarize ...read more
Chalcogen-modified nucleic acid analogues
Chalcogen-modified nucleosides, nucleotides and oligonucleotides have been of great interest to scientific research for many years. The replacement of oxygen in the nucleobase, sugar or phosphate backbone by chalcogen atoms (sulfur, selenium, tellurium) gives these biomolecules unique properties resulting from their altered physical and chemical properties. The continuing interest in ...read more
Current advances in inherited cardiomyopathy
Describe in detail all novel advances in multimodality imaging related to inherited cardiomyopathy diagnosis and prognosis. Shed light to deeper phenotypic characterization. Acknowledge recent advances in genetics, genomics and precision medicineread more
- Author Guidelines
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers
- Announcements
Related Articles
-
Anti-breast Cancer Agents, Quinolines, Targeting Gap Junction
Medicinal Chemistry Mechanisms of Tubulin Binding Ligands to Target Cancer Cells: Updates on their Therapeutic Potential and Clinical Trials
Current Cancer Drug Targets In Situ Gene Therapy for Prostate Cancer
Current Gene Therapy The Monoaminergic Tripartite Synapse: A Putative Target for Currently Available Antidepressant Drugs
Current Drug Targets An Integrative Informatics Approach to Explain the Mechanism of Action of N1-(Anthraquinon-2-yl) Amidrazones as BCR/ABL Inhibitors
Current Computer-Aided Drug Design Encountering and Advancing Through Antiangiogenesis Therapy for Gliomas
Current Pharmaceutical Design Cognitive, Psychological and Psychiatric Effects of Ionizing Radiation Exposure
Current Medicinal Chemistry Graphene Oxide: A Carrier for Pharmaceuticals and a Scaffold for Cell Interactions
Current Topics in Medicinal Chemistry Protection Mechanisms Against Aβ42 Aggregation
Current Alzheimer Research Osteopontin is a Prognostic Factor in Patients with Advanced Gastric Cancer
Combinatorial Chemistry & High Throughput Screening PET Molecular Imaging of Hypoxia in Ischemic Stroke: An Update
Current Vascular Pharmacology Endocannabinoid System: Emerging Role from Neurodevelopment to Neurodegeneration
Mini-Reviews in Medicinal Chemistry Magnetic Field-Assisted Gene Delivery: Achievements and Therapeutic Potential
Current Gene Therapy Recent Evidence of the Regulatory Role of PPARs in Neural Stem Cells and Their Underlying Mechanisms for Neuroprotective Effects
Current Stem Cell Research & Therapy Biosafety of Herpesvirus Vectors
Current Gene Therapy The Inverse Relationship Between Cancer and Alzheimer's Disease: A Possible Mechanism
Current Alzheimer Research Copper Complexes as Anticancer Agents
Anti-Cancer Agents in Medicinal Chemistry Bone Marrow Mesenchymal Stem Cells: Agents of Immunomodulation and Neuroprotection
Current Stem Cell Research & Therapy Radionuclide Liver Cancer Therapies: From Concept to Current Clinical Status
Anti-Cancer Agents in Medicinal Chemistry Histone Deacetylase (HDAC) Inhibitors - emerging roles in neuronal memory, learning, synaptic plasticity and neural regeneration
Current Neuropharmacology