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Letters in Organic Chemistry

Editor-in-Chief

ISSN (Print): 1570-1786
ISSN (Online): 1875-6255

Revisit: Eaton’s Reagent Catalyzed Synthesis of Mono and Bis-Chalcone Derivatives

Author(s): Shrikrishna. D. Tupare, Santosh V. Nalage, Sharad R. Bobe, Shivshankar N. Hallale, Sheshanath V. Bhosale, Sanjay K. Vyawahare, Satish A. Dake, Sidhanath V. Bhosale and Rajendra P. Pawar

Volume 9, Issue 7, 2012

Page: [526 - 529] Pages: 4

DOI: 10.2174/157017812802139627

Abstract

Eaton’s reagent efficiently catalyzed the Claisen-Schmidt condensation reaction of aryl aldehydes with aromatic and cyclic ketones under solvent free microwave irradiation conditions to afford mono and bis-chalcone derivatives. The present approach offers several advantages such as shorter reaction times, cleaner reactions, good yields, inexpensive reagent and mild reaction conditions.

Keywords: Aromatic aldehydes, aromatic ketone, chalcones, cyclic ketone, eaton’s reagent, solvent-free, fused pyridines, thiazines, pyrimidines, iodine


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