Abstract
Spurred by remarkable findings in animal studies, there has been strong interest in evaluating the potential of adult stem cells to improve left ventricular function in the past decade. Driven by the need to treat the increasing number of patients with coronary artery disease, numerous studies have attempted to define a role for bone marrow cell therapy in clinical use. However, the conflicting results of these studies can be confusing. This article will review the landmark trials evaluating bone marrow cell therapy in the past decade and describe the current state of adult stem cell therapy and its future direction herein.
Keywords: Bone marrow cell therapy, stem cell therapy, cardiac MRI, molecular imaging, human amniotic mesenchymal stem cells, mesenchymal stem cells, paracrine effect.
Reviews on Recent Clinical Trials
Title:Bone Marrow Cell Therapy in Clinical Trials: A Review of the Literature
Volume: 7 Issue: 3
Author(s): Paul J. Kim and Phillip C. Yang
Affiliation:
Keywords: Bone marrow cell therapy, stem cell therapy, cardiac MRI, molecular imaging, human amniotic mesenchymal stem cells, mesenchymal stem cells, paracrine effect.
Abstract: Spurred by remarkable findings in animal studies, there has been strong interest in evaluating the potential of adult stem cells to improve left ventricular function in the past decade. Driven by the need to treat the increasing number of patients with coronary artery disease, numerous studies have attempted to define a role for bone marrow cell therapy in clinical use. However, the conflicting results of these studies can be confusing. This article will review the landmark trials evaluating bone marrow cell therapy in the past decade and describe the current state of adult stem cell therapy and its future direction herein.
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Cite this article as:
Kim J. Paul and Yang C. Phillip, Bone Marrow Cell Therapy in Clinical Trials: A Review of the Literature, Reviews on Recent Clinical Trials 2012; 7 (3) . https://dx.doi.org/10.2174/157488712802281286
DOI https://dx.doi.org/10.2174/157488712802281286 |
Print ISSN 1574-8871 |
Publisher Name Bentham Science Publisher |
Online ISSN 1876-1038 |
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