Abstract
Cardiovascular disease (CVD) is the leading cause of mortality and morbidity among diabetics. Vitamin D deficiency is very common all over the world. Over last few years, vitamin D has been considered as an important regulating factor for cardiovascular health. Metabolic syndrome and obesity are highly prevalent in vitamin D deficient people. In fact all components of metabolic syndrome are affected by vitamin D. Vitamin D regulates insulin secretion and its action. It has also some controlling effect on Renin-Angiotensin system, which influences cardiomyocytes positively. Vitamin D plays a role in vascular system too. This vitamin reduces vascular calcification and inflammatory processes. Given the important role of Vitamin D in cardiovascular health, this review focuses on the impacts of vitamin D on the various CVD risk factors.
Keywords: Albuminuria, Cardiovascular Disease, congestive heart failure, Diabetes, hypertension, inflammation, insulin resistance, Metabolic Syndrome, obesity, Vitamin D
Cardiovascular & Hematological Agents in Medicinal Chemistry
Title:Diabetic CVD – Focus on Vitamin D
Volume: 10 Issue: 3
Author(s): Shokoufeh Bonakdaran and Haleh Rokni
Affiliation:
Keywords: Albuminuria, Cardiovascular Disease, congestive heart failure, Diabetes, hypertension, inflammation, insulin resistance, Metabolic Syndrome, obesity, Vitamin D
Abstract: Cardiovascular disease (CVD) is the leading cause of mortality and morbidity among diabetics. Vitamin D deficiency is very common all over the world. Over last few years, vitamin D has been considered as an important regulating factor for cardiovascular health. Metabolic syndrome and obesity are highly prevalent in vitamin D deficient people. In fact all components of metabolic syndrome are affected by vitamin D. Vitamin D regulates insulin secretion and its action. It has also some controlling effect on Renin-Angiotensin system, which influences cardiomyocytes positively. Vitamin D plays a role in vascular system too. This vitamin reduces vascular calcification and inflammatory processes. Given the important role of Vitamin D in cardiovascular health, this review focuses on the impacts of vitamin D on the various CVD risk factors.
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Cite this article as:
Bonakdaran Shokoufeh and Rokni Haleh, Diabetic CVD – Focus on Vitamin D, Cardiovascular & Hematological Agents in Medicinal Chemistry 2012; 10 (3) . https://dx.doi.org/10.2174/187152512802651088
DOI https://dx.doi.org/10.2174/187152512802651088 |
Print ISSN 1871-5257 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-6182 |
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Medicinal Plants with Beneficial Properties on Diabetes and Hypertension
Diabetes and hypertension are real scourges of the 21st century. It is imperative to act in order to find innovative solutions to this problem. Taking medications such as hypoglycemic and antihypertensive drugs may aggravate certain underlying comorbidities, such as chronic kidney disease and cardiovascular disease. This significant drawback therefore requires ...read more
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