Generic placeholder image

Letters in Organic Chemistry

Editor-in-Chief

ISSN (Print): 1570-1786
ISSN (Online): 1875-6255

An Efficient Green MCR Protocol for the Synthesis of New Betti Bases via Mannich-Type Reaction

Author(s): Abolfazl Olyaei, Mojgan Zarnegar, Mahdieh Sadeghpour and Mortaza Rezaei

Volume 9, Issue 6, 2012

Page: [451 - 456] Pages: 6

DOI: 10.2174/157017812801322499

Abstract

An efficient solvent and catalyst-free synthesis of new Betti base derivatives via Mannich-type one-pot threecomponent condensation reaction of aminodiazines, salicylaldehyde and naphthols under solvent-free conditions is described. The reactions occur at 80 oC giving high to excellent yields of the products. The work-up procedure is very simple and the products do not require further purification with column chromatography.

Keywords: Aminodiazine, Betti base, naphthol, salicylaldehyde, solvent-free, three- component, 2-aminopyrimidine, temperature, aminonaphthols


© 2024 Bentham Science Publishers | Privacy Policy