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Letters in Drug Design & Discovery

ISSN (Print): 1570-1808
ISSN (Online): 1875-628X

Volume 19, Issue 12, 2022

This journal supports open access

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Editorial Board


lddd Editor-in-Chief lddd_ebm_Cacciatore_001 Cacciatore Ivana Department of Pharmacy University "G. d'Annunzio" of Chieti-Pescara Chieti Scalo Italy

Prof. Ivana Cacciatore received her master’s degree in Pharmaceutical Chemistry and Technology in 1999 from the University of Chieti-Pescara (Italy). In 2002 she obtained her Ph.D. in Pharmaceutical Science. Currently, she is Associate Professor of Medicinal Chemistry at the Department of Pharmacy, University of Chieti-Pescara. She is co-founder and member of the Board of Directors of the Spin Off Company "Algo Biotechnologies" holding the role of Chief Innovation Officer (CIO). Her research interests are drug design and discovery, medicinal chemistry, pharmacology, etc. Her research is well documented in more than 90 papers published in peer-reviewed international scientific Journals.

ivana.cacciatore@unich.it
Co-Editors lddd_ebm_kamil_001 Kuca Kamil University of Hradec Kralove Hradec Kralove Czech Republic

Kamil Kuca is working for several academic institutes (University of Hradec Kralove, Czech Republic; University Hospital Hradec Kralove, Czech republic; Florida International University, USA; Yangtze University, China; etc.). He is recently rector of the University of Hradec Kralove. He was also technology scout focused on biomedicine in the past. His research interests are toxicology, pharmacology, drug design, technology transfer, pharmacoeconomy, chemical and biological terrorism, etc. He is principal investigator on numerous national and international projects (EU, NATO, GACR, IGA MZ, MSMT etc.). He has published more than 350 IF research papers. He is working with several companies as a scientific consultant. He has lots of cooperators throughout the world (e.g. Korea, Croatia, United Arab Emirates, USA, France, Turkey, China, Singapore, Sweden, and Brazil). His H-index is 36, and the number of citation in WoS is over 3000.

Wu Wenda College of Veterinary Medicine Nanjing Agricultural University Nanjing China wuwenda@njau.edu.cn lddd_ebm_s-r-khan_001 Khan Saeed R. Department of Research and Development Vikor Scientific, LLC. Charleston SC USA

Dr. Khan obtained a doctorate (Ph.D.) in Medicinal Chemistry from the University of Texas MD Anderson Cancer Center, Houston. Currently, he is a senior Scientist at FDA and an Adjunct Professor in the Johns Hopkins University of Medicine. He has published more than 60 scientific publications and is a named inventor of 10 issued U.S/international patents.

Khansa@jhmi.edu
Associate Editors lddd_ebm_Marinelli-l_001 Marinelli Lisa Department of Pharmacy University of G. d'Annunzio Chieti and Pescara Chieti Italy

Dr. Lisa Marinelli is an Assistant Professor at the Department of Pharmacy, G. D’Annunzio University of Chieti-Pescara, Italy. The research interest of Lisa Marinelli is focused on Pharmaceutical Technology including preparation and characterization of drug delivery systems useful for the treatment of neurodegenerative and microbial diseases. Her research activity is well documented by many papers published in peer-reviewed international scientific journals.

l.marinelli@unich.it
lddd_ebm_Di-Stefano_001 Di Stefano Antonio Department of Pharmacy University of Chieti-Pescara Chieti Italy

Antonio Di Stefano graduated in Chemistry and Pharmaceutical Technology (CTF) at the University of Camerino, Italy, in April 1989; and in April 1995, he graduated in Pharmacy at University of Camerino. He gained his Ph.D. in “Medicinal Chemistry” in June 1994. From February 1994 to January 1995 he worked as C.N.R. (Research National Council-Rome, Italy) project researcher, working on the synthesis of new Dopaminergic ligands. From March 1995 to March 1996 he was appointed as Post-Doc researcher on the “Synthesis of new dopaminergic ligands”. In December 2003 he got a permanent position as Associate Professor of Pharmaceutical Technology at the Faculty of Pharmacy of the University of Chieti-Pescara, Italy. Since 2011 he has been holding the position of Full Professor on Pharmaceutical Technology, Socioeconomics and Legislation (03/D2) in the same University. The research activity is well documented in more than 150 papers published in peer-reviewed International Journals, Patents, Book Chapters, Proceedings, National and international oral Communications. Prof. Antonio Di Stefano is C.E.O. of spin-off “Algo Biotechnologies” (“G. d’Annunzio” Chieti-Pescara University) to select and develop the most attractive ideas in the pharmaceutical field based on the proprietary algorithm probability factor.

antonio.distefano@unich.it
lddd_ebm_banik_001 Banik B.K. Prince Mohammad Bin Fahd University Al Khobar Kingdom of Saudi Arabia

Dr. Banik is a Professor of Natural Sciences at the Prince Mohammad Bin Fahd University in Kingdom of Saudi Arabia. He had worked as the Vice President of Research & Education Development of Community Health Systems of South Texas and as a Tenured Full Professor and First President’s Endowed Professor at the University of Texas-Pan American. Professor Banik is deeply engaged in multiple areas of higher education. The principal areas of Professor Banik’s research are synthesis and medicinal evaluation of β-Lactams and polyaromatic compounds. As the Principal Investigator, he has been awarded $7.25 million in grants from the NIH and NCI. Importantly, he has 370 publications along with 465 presentation abstracts. He is the editor-in-chief of 12 journals. Professor Banik has received many national and international awards.

lddd_ebm_fang_001 Fang H. Shandong University Ji'nan China

Dr. Fang obtained a doctorate in China Pharmaceutical University in 2001. Currently he is professor of medicinal chemistry and vice director of Scientific Research and International Affairs of Shandong University Cheeloo College of Medicine. His research focused on structure-based drug design on the targets for cancer therapy, including histone deacetylase (HDAC), Bcl-2 and Cyclin-dependent kinase (CDK) etc. Notably, Dr. Fang has authored more than 70 scientific publications, and is a named inventor of 10 issued China patents.

lddd_ebm_keglevich_001 Keglevich G. Budapest University of Technology and Economics Budapest Hungary

György Keglevich graduated as a chemical engineer. He has been Professor of Chemistry since 1995, and the Head of the Department of Organic Chemistry and Technology, Budapest Univesity of Technology since 1999. He is engaged with P-heterocyclic and environmentally-friendly chemistry comprising MW chemistry, phase transfer catalysis and the development of new catalysts. He is the author or co-author of 460 papers He holds editorial positions at the journals Curr. Green Chem., Cur. Org. Chem., Lett. Org. Chem., Curr. Org. Synth.. Lett. Drug Des. Disc. and Curr. Catal. He is the member of the Editorial Board of Heteroatom Chem . and Phosphorus Sulfur Silicon.

Makriyannis A. Northeastern University Boston MA USA
Regional Editors Asia lddd_ebm_h-liu_001 Liu X.-H. Zhejiang University of Technology Hangzhou China

Dr. Liu obtained a doctorate (Ph.D.) in Chemistry from Nankai University. Currently, Dr. Liu is an Associate Professor in the Zhejiang University of Technology, College of Chemical Engineering and as Visiting Scientist of US Department of Agriculture, Agricultural Research Service, Natural Product Centre. He has published more than 100 scientific papers and is a named inventor of more than 40 authorized CN patents. He is currently involved in the editorial board of Letters in Drug Design & Discovery, Asian Journal of Chemistry and Scholars Research Library.

lddd_ebm_okada_001 Okada Y. Kobe Gauin University Nishi-ku Japan

Dr. Yoshio Okada is a Professor Emeritus of Kobe Gakuin University. He obtained PhD. Degree in Medicinal Chemistry from Kyoto University, Kyoto Japan. His research is the development of analgesic, anti-cancer and anti-plasmin drugs based on the peptide chemistry. He has already published more than 230 scientific publications. He was the president of Japanese Peptide Society from April of 2002 to March of 2004 and is an honorary member of that society.

Australia/New Zealand lddd_ebm_mancera_001 Mancera R.L. Curtin University of Technology Perth Australia

"Prof. Ricardo Mancera did his undergraduate degree in biological and pharmaceutical chemistry from the National University of Mexico and his PhD in theoretical and computational chemistry from the University of Cambridge. He worked as a research fellow in the Department of Pharmacology at the University of Cambridge, senior research scientist at De Novo Pharmaceuticals and is currently a professor of Biophysical Chemistry and Computational Biophysics at Curtin University, Perth, Australia."

North America lddd_ebm_balasubramanian_001 Balasubramanian K. Arizona State University Tempe AZ USA

Prof. Krishnan Balasubramanian obtained his Ph.D. degree in 1981 from Johns Hopkins University, Baltimore, Maryland, USA. Dr. Balasubramanian is currently Professor Emeritus at Arizona State University, Tempe, Arizona, USA. His primary areas of research include theoretical chemistry, mathematical chemistry and computer chemistry, while the secondary areas are computational biology, predictive toxicology and drug research. Dr. Balasubramanian, as an author/co-author, has published more than 520 articles in various journals of international repute, having significant number of total citations, i.e. over 11,730. He has received the following major awards/honors: Two-time Fulbright Scholar; Camille and Henry Dreyfus Teacher-Scholar; Alfred P. Sloan Fellow; Joint Prize of Minister of Education, Poland.

lddd_ebm_neumeyer_001 Neumeyer J.L. McLean Hospital Belmont MA USA

John l. Neumeyer received the BS degree from Columbia University and the PH.D in Medicinal Chemistry from the University of Wisconsin. He co-founded research biochemicals int. (rbi) And has over 40 0years’ experience in the industry and academia. He is a fellow of the ACS, AAPS and AAAs, and was elected to the hall of fame of the division of medicinal chemistry, ACS. He has published over 300 scientific publications and has been awarded 27 us patents.

lddd_ebm_honek_001 Honek J.F. University of Waterloo Waterloo ON Canada

Dr. Honek is a professor in the Department of Chemistry, University of Waterloo, Canada. He obtained his B.Sc./Ph.D. degrees from McGill University. His Ph.D. research (supervisor: Dr. Bernard Belleau), focused on the design and synthesis of sulfur-based heterocyclic analogs of the anthracycline antibiotics. Postdoctoral research (MIT; supervisor: Dr. Christopher Walsh) explored the enzyme mechanisms involved in microbial methane production. Dr. Honek’s research is focused on the biological chemistry of the carbon-sulfur bond and on protein structure and function. He is the author of numerous publications including a recent textbook (Biochemical Pharmacology by Palmer, Chan, Dieckmann & Honek, (2012) Wiley-VCH). He is the recipient of the Canadian Society for Chemistry Bernard Belleau Award (2014) for distinguished contributions to the field of medicinal chemistry.

Section Editors Medicinal Plants Alan Yusuf Orcid Department of Molecular Biology and Genetics Muş Alparslan University Muş Turkey

Dr. Yusuf Alan received his master's degree in Biology from Sütcü Imam University (Turkey) in 2010. He received his PhD in Biology in 2014. He is currently working as an Associate Professor of Biology in the Department of Molecular Biology and Genetics at Muş Alparslan University (Turkey). His research interests include phenolic content of extracts obtained from medicinal plants, in vitro DNA damage, antimicrobial, anticancer and antioxidant activities.

Anti-cancer Agents Cevik Ulviye ACAR Orcid Department of Pharmaceutical Chemistry Anadolu University Eskişehir Turkey

Dr. Acar Çevik has been working in Anadolu University Faculty of Pharmacy Department of Pharmaceutical Chemistry for the past 8 years. She has published 54 articles in the international peer-reviewed journals indexed by Science Citation Index (SCI) and SCI-Expanded, 12 articles published in national peer-reviewed journals and 40 research projects. There are 63 papers presented in national and international congresses. She has received 6 rewards from Anadolu University, namely article Performance Award. Besides, she has also received a bronze medal at the International Invention Competition organized within the scope of the 6th Istanbul International Invention Fair. She has one national patent to her credit. Her research field is the design and synthesis of new carbonic anhydrase (hCA) inhibitors, cholinesterase (ChE) inhibitors, anticancer, antimicrobial, anti-inflammatory and monoamine oxidase agents.

Capasso Anna Department of Pharmacology University of Salerno Salerno Italy Pharmacology annacap@unisa.it lddd_ebm_lima-lm_001 Computational Strategies Applied to Drug Design Lima Lídia M. Orcid Federal University of Rio de Janeiro Rio de Janeiro Brazil

Dr. Lidia Moreira Lima is a Full Professor of Federal University of Rio de Janeiro (UFRJ). She studied Pharmacy and got the MSc and D.Sc. degrees from Chemistry Institute of UFRJ. From 2002 to 2013, she was an Associate Professor at the Faculty of Pharmacy in UFRJ (Brazil). She conducted post-doctoral research in the Department of Pharmaceutical Chemistry at the University of Navarra (Spain) under the supervision of Professor Antonio Monge. She is the coordinator of the postgraduate program in pharmacology and medicinal chemistry at the Institute of Biomedical Sciences of UFRJ. Her scientific interests focus on molecular design, synthesis, metabolism study and lead-optimization of new drug candidates for cancer, diabetes, inflammatory and neglected diseases.

0000-0002-8625-6351 https://publons.com/researcher/2419447/lidia-m-lima/publications/# https://scholar.google.com/citations?user=Rhp0JhwAAAAJ lmlima23@gmail.com
In-silico Drug Design lddd_ebm_Agamennone_001 Agamennone Mariangela Department of Pharmacy University “G. d’Annunzio” of Chieti Chieti Italy 6506766137 0000-0001-5198-0051 https://www.unich.it/ugov/person/850 https://scholar.google.com/citations?hl=en&user=V0dqytwAAAAJ https://pubmed.ncbi.nlm.nih.gov/?term=agamennone+mariangela

Dr. Agamennone has been an Assistant Professor of Medicinal Chemistry in the Department of Pharmacy, University “G. d’Annunzio” of Chieti, Italy, since 2005. Her research activity focuses on computational methods such as molecular mechanics, docking, pharmacophore modeling, chemoinformatics, (3D-) QSAR, molecular dynamics, applied to the various phases of the drug design and discovery process. Principal research topics concern cancer and neurodegeneration, viral infections (Influenza), antibiotic resistance, and cancer immunotherapy

m.agamennone@unich.it
lddd_ebm_Pierluigi-ab_001 Anti-cancer drugs Scalia Pierluigi ISOPROG-Somatolink Foundation EPFP Research Network Philadelphia, PA 19102 USA

Pierluigi Scalia MD PhD is the director and co-founder of the ISOPROG-Somatolink EPFP-PGM Network Philadelphia USA 19102 and Caltanissetta Italy 93100. He is also Adjunct Assistant Professor at the Sbarro Institute for Cancer Research and Molecular Medicine Temple University, College of Science and Technology, Biology Division Philadelphia, USA. Dr. Scalia has spent two decades in the biomedical research setting with several publications in peer-reviewed scientific journals, including Oncogene, Cancers, Blood, Current Biology, International Journal Cancer, Genes and Molecular and Cellular Biology. He has fifteen years of research and development experience in academic and private sectors with internationally patented research on the role of cancer microenvironmental factors on tumor progression and biomarker discovery and validation. Dr. Pierluigi's professional focus relates to several areas of biomolecular research and translational sciences to bring innovative discoveries and sound therapeutic solutions to the applicative level in the area of Personalized Cancer Medicine.

Frontiers Section Editors lddd_ebm_s-thareja_001 Thareja S. Guru Ghasidas Central University Bilaspur India

Dr. Suresh Thareja is an Assistant Professor of Medicinal Chemistry at School of Pharmaceutical Sciences, Guru Ghasidas Central University, Bilaspur, India. He received his PhD degree in Pharmaceutical Chemistry from Panjab University, India (2011) and Postdoctoral training in Dr. Binghe Wang’s lab at Georgia State University (2016-2017). He also worked as Scientific writer-II in Novartis Pharmaceuticals. He is the recipient of many reputed fellowships including Raman Fellowship for research in USA. His research focused on computer-aided drug design as well as synthesis and biological evaluation of novel PTP-1B inhibitors, steroidal 5α-reductase inhibitors and agents for cancer therapy, Dr. Thareja has authored more than 45 scientific publications in peer reviewed journals along with an international Patent.

Medicinal Chemistry
Editorial Board Members lddd_ebm_robert-ancuceanu_001 Ancuceanu Robert Department of Pharmaceutical Botany and Cell Biology University of Medicine and Pharmacy "Carol Davila" Bucharest Romania

Robert Ancuceanu is a professor in the Bucharest Faculty of Pharmacy, Carol Davila University of Medicine and Pharmacy, where he teaches Cell and Molecular Biology and Pharmaceutical Botany and is currently a vice-dean. He has a PhD in pharmacy, a master's in biostatistics and a BSc in law. He has worked in different pharmaceutical domains, from academic to industrial and regulatory. He has published over 75 scientific papers of which 68 are indexed in ISI Clarivate, two books as a single author and is a co-author or chapter author of 13 books.

lddd_ebm_altıntop-sh_001 ALTINTOP M.D. Orcid Anadolu University Eskisehir Turkey 0000-0003-0280-5550

Dr. Altintop has been working in Anadolu University Faculty of Pharmacy Department of Pharmaceutical Chemistry for past 10 years. She has published 70 articles in the international peer-reviewed journals indexed by Science Citation Index (SCI) and SCI-Expanded, 12 articles published in national peer-reviewed journals and 35 research projects. She has received 3 rewards from Anadolu University, namely Science and Technology Encouragement Award in 2014, Gold Article Performance Award and Platinum Article Performance Award in 2016. She has also received an Outstanding Reviewer Award from European Journal of Medicinal Chemistry (Elsevier) in 2016 and Encouragement Award from Turkish Pharmacists’ Association Academy of Pharmacy in 2019. Her research field is the design and synthesis of new carbonic anhydrase (hCA) inhibitors, cholinesterase (ChE) inhibitors, anticancer, antimicrobial, antinociceptive, anti-inflammatory and antidepressant agents.

mdaltintop@anadolu.edu.tr
lddd_ebm_wu_q_at_001 Wu Q. Yangtze University Jingzhou China

Dr. Qinghua Wu obtained the doctor's degree from Huazhong Agricultural University, China in 2013. During 2010-2011, Dr. Wu has studied as a visiting scholar at the Institute of Food Chemistry, University of Muenster, Germany. Since 2014, he is an invited professor in University of Hradec Kralove. Since 2015.07, he began to be an associate professor in Yangtze University. His research interest is metabolism, pharmacokinetics, toxicokinetics, immunotoxicity, and food safety. Dr Wu has published more than 40 peer-reviewed articles in the field of metabolism and toxicology.

wqh212@hotmail.com
lddd_ebm_khan_m_at_001 Khan M. Abdul Wali Khan University Mardan Mardan Pakistan

Dr. Momin Khan currently working as an Associate Professor at Department of Chemistry Abdul Wali Khan University Mardan Pakistan. He got his doctoral degree in Organic Medicinal Synthetic Chemistry from HEJ Research Institute, University of Karachi Pakistan in 2011. Dr. Khan completed six months postdoc from the University of Bristol UK, in 2014. Dr. Khan is working on the synthesis of medicinally important heterocyclic compounds, having enzyme inhibition properties. Dr. Momin published fifty eight (58) research articles in impact factor international peer reviewed journals in addition to publication of a US Patent on medicinal chemistry. He has one (01) Ph.D, thirty-two (32) M.Phil and forty four (44) undergraduate students. Currently five Ph.Ds. and eight M. Phil research scholars are working under his supervision.

http://goo.gl/bR5lIf https://scholar.google.com/citations?user=FK93Cc0AAAAJ&hl=en&authuser=2
lddd_ebm_tuccinardi-t_001 Tuccinardi T. Orcid University of Pisa Pisa Italy 6507524571 0000-0002-6205-4069 http://www.mmvsl.it/wp/group-members/tuccinardi/

Tiziano Tuccinardi is an Associate Professor of Medicinal Chemistry at the Department of Pharmacy of the University of Pisa. Since July 2016 he is also Adjunct Associate Professor at the Department of Biology, Temple University’s College of Science and Technology, Philadelphia, PA, USA. He has published more than 150 papers, five patents and he is a scientific advisory board member of the Bio Future Medicine (BFM) start-up. His research interests include drug and lead discovery, with a focus on computer-assisted approaches and medicinal chemistry, including synthesis of small molecules, virtual and biomolecular screening.

lddd_ebm_rinaldi-f-ah_001 Rinaldi F. “Sapienza” University of Rome Rome Italy

Dr. Rinaldi’s research activity is mainly focused on the study of phospholipid and non-phospholipid vesicles as drug delivery systems. Dr Rinaldi has been involved not only in preparation and characterization of vesicular systems for different application, but also in application studies by in vitro cellular evaluation and in vivo of drug delivery systems. Currently her research is focused on preparation and characterization of novel drug delivery systems (nanoemulsions) composed by essential oil and natural active compounds.

lddd_ebm-kakkar-r-ah_001 Kakkar R. University of Delhi Delhi India lddd_ebm-soriano-ursua-ah_001 Soriano-Ursua M.A. Escuela Superior de Medicina Mexico City Mexico

Marvin A Soriano-Ursúa has completed his PhD from Escuela Superior de Medicina del Instituto Politénico Nacional, México. He is a member of the National System of Researchers, and head of the Physiology Laboratory. He has focused on the rational drug design having boron-containing compounds as main moiety, as well as the different effects of these compounds on human physiology, particularly on G-Protein coupled receptors. He has authored more than 50 publications, and has been serving as an editorial board member and reviewer of a number of reputed scientific journals.

lddd_ebm-zhou-p_001 Zhou P. University of Electronic Science and Technology of China (UESTC) Chengdu China 56688039200

Dr. Peng Zhou is an Associate Professor of Bioinformatics at University of Electronic Science and Technology of China (UESTC). He received his Ph.D. from Zhejiang University, P.R.China in 2011. From 2012 to 2013, he worked as a Post Doctor in U.S. Food and Drug Administration (FDA), USA. He has published over 100 peer-reviewed papers in SCI-indexed journals. His publications have been cited over 1,500 times with H-index of 25 in Google Scholar.

lddd_ebm_suntar-i-rab_001 Suntar I. Gazi University Ankara Turkey

Dr. Ipek Suntar is an Associate Professor at the Department of Pharmacognosy, Faculty of Pharmacy, Gazi University, Ankara, Turkey. She got her bachelors, M.Sc. and PhD. Degrees from the same University. She conducted a part of her PhD. studies in University of Wolverhampton, UK, by obtaining scholarship from Scientific and Technological Research Council of Turkey (TUBITAK). Her research field mainly focuses on the investigation of the in vivo wound healing, anti-inflammatory, antinociceptive, anti-endometriotic and anti-urolithiatic activities of the natural sources used in traditional medicine through biological activity-guided fractionation and isolation assays. She has published 80 scientific articles (SCI and SCI-exp. indexed) and 10 book chapters. She is a member of Society for Medicinal Plant and Natural Product Research (GA), (PSE) and (AMAPSEEC)

lddd_ebm_carvalho-lbde-rab_001 Carvalho L.B.de University of Coimbra Coimbra Portugal

Luís A.E. Batista de Carvalho obtained his B.Sc. degree in Chemistry from the University of Coimbra, and his Ph.D. in Physical Chemistry (1993) from the University of Lisbon, Portugal. Currently he is an Assistant Professor at the Chemistry Department of the University of Coimbra and coordinator of the “Molecular Physical Chemistry” R&D Unit. He has authored more than 100 scientific publications in ISI-indexed journals. His main current research interests are focused on the application of vibrational spectroscopy techniques to the study of biological samples (e.g. cells, biofluids and tissues), in order to probe changes (chemical as well as structural and dynamical) induced by chemotherapeutic agents, environmental conditions (e.g. burning events) or pathological disorders.

lddd_ebm_byun-y_001 Byun Y. Korea University Sejong City South Korea

Youngjoo Byun received B.S and M.S degrees from Seoul National University and Ph.D from Ohio State University. He is now full Professor at College of Pharmacy, Korea University, South Korea. Before joining Korea University, Dr Byun worked at Johns Hopkins University School of Medicine from 2006 to 2011. He has published more than 80 peer-reviewed papers. His research focuses on discovery of bioactive molecules and structural optimization of hit compounds.

lddd_ebm_m-pissarek_001 Pissarek M. Research Center Julich Institute of Neurosciences and Medicine Jülich Germany

Dr. Margit Pissarek is currently an Assistant Professor and Physician at the Institute of Neurosciences and Medicine at Research Centre Jülich, Germany (since 1998). Dr. Pissarek received her M.D. in 1983 from the Humboldt University Berlin, Germany, and then performed her services in the Institute of Biochemistry (Humboldt University), the Clinic of Cardiovascular Surgery (University Leipzig, Germany), the Institute of Molecular Pharmacology (Berlin, Germany), the Laboratoire de Signalisation et Physiopathologie Cardiovasculaire (University Paris-Sud, France), and the Rudolf-Boehm-Institute of Pharmacology (Leipzig). She is specialized in biochemistry as well as in pharmacology and toxicology. Currently, she is concerned with development of tracers for positron-emission-tomography focused on cerebral neuropeptide receptors.

lddd_ebm_ben_001 Dal Ben D. University of Camerino Camerino Italy

Diego Dal Ben got PhD in Pharmaceutical Sciences at the University of Padova (Italy) then moved to the University of Camerino (Italy). Dr. Dal Ben is currently Associate Professor of Medicinal Chemistry and leader of the Drug Design Team molecular modelling group. His research work is to design and optimize bioactive compounds with molecular modelling tools. His studies are focused mainly to membrane proteins belonging to the GPCR (Purinergic P1 Receptors) and ion channel (Purinergic P2X Receptors) protein families. Further studies are related to compounds able to modulate the activity of enzymes (i.e. Topoisomerases and Kinases).

Mollica A. University "G. D' Annunzio" of Chieti-Pescara Chieti Italy lddd_ebm_saad_001 Tayyab S. University of Malaya Kuala Lumpur Malaysia

Saad Tayyab obtained B.Sc. (Hons.) Chemistry (1979), M.Sc. Biochemistry (1981), M.Phil. Biochemistry (1983) and Ph.D. Biochemistry (1987) from Aligarh Muslim University, India. Currently he is working as a Professor of Biochemistry at the Institute of Biological Sciences, University of Malaya, Malaysia since 2004. He has published more than 100 scientific publications in ISI-indexed journals. He has served as the Editorial Board Member of the Bioscience Education e Journal, UK (2008–2011), Indian Journal of Clinical Biochemistry (2002–2004) and Journal of the Assam Science Society, India (2003–2005). Currently, he is serving as the Editor-in-Chief, Malaysian Journal of Biochemistry and Molecular Biology (since 2015), Editorial Board Member of Biochemistry Research International (since 2013), Letters in Drug Design & Discovery (2015), International Journal of Biological Chemistry (since 2008) and Asian Journal of Biochemistry (since 2008).

lddd_ebm_silvestri_001 Silvestri R. Sapienza University Rome Italy

Prof. Romano Silvestri obtained a doctorate (Ph.D.) in Pharmaceutical Sciences from the University of Rome La Sapienza. He is a full professor of medicinal chemistry at the University La Sapienza and the director of the school of specialization in hospital pharmacy. He is a member of the scientific council of Institute Pasteur Italy. His research projects focused on the drug design and synthesis and molecular models of new antitumor, antiviral and endocannabinoid ligands. He developed new procedures for the microwave-assisted synthesis and the highly automated purification of relevant pharmaceutical molecules. He has published more than 135 research articles and 10 patents. He is a co-inventor of 10 patents.

lddd_ebm_barreiro_001 Barreiro E. Universidade Federal do Rio de Janeiro Rio de Janeiro Brazil

Professor Barreiro obtained a doctorate (Docteur d´Étát) in Chemistry from the University of Grenoble, France (1978). Dr. Barreiro is Full-Professor of Medicinal Chemistry at Federal University of Rio de Janeiro (UFRJ), Rio de Janeiro city, Brazil from 1984. He is author/co-author of more than 300 scientific papers, published in peer-reviewed journals is founder and the Scientific Director of Laboratory of Synthesis and Bioassays of Bioactive Substances at UFRJ, Brazil.

lddd_ebm_musumeci-f_001 Musumeci F. University of Genoa Genoa Italy

Dr. Francesca Musumeci received her PhD in Medicinal Chemistry from the University of Genoa (Italy) in 2012. Since then, she has a Postdoctoral position at the University of Genoa (Prof. Schenone’s group) working at the synthesis of heterocyclic compounds potentially active as anticancer or antiviral agents. Her professional experiences include two visiting research fellowships, at National University of Ireland in Galway and at the University of Nottingham. She is author of 40 publications on international journals and a patent. She recently obtained the National Scientific Habilitation as an Associate Professor in Medicinal Chemistry.

lddd_ebm_brenner_001 Brenner C. Université Paris-Sud Orsay France

Catherine Brenner is expert in Biochemistry and Cell Biology of Cell Death. She discovered the cooperation of Bax and ANT in mitochondrial apoptosis and investigated the role of the permeability transition pore, a mitochondrial polyprotein complex, as a target for anti-cancer chemotherapy. Since 2010, her research interests focus on the role of mitochondria in signalisation and cardiac pathophysiology and the search for novel strategies in cardioprotection via an inhibition of cell death.She coordinated several international and national research programs in the field of drug discovery with academic as well as biotech partners (ANR PCV, ANR France-Portugal, Labex LERMIT). As a scientist, she published more than 140 articles, reviews and books. She is currently editor for five journals and reviewer for more than 30 journals.

lddd_ebm_brunel_001 Brunel J.M. Université de la Méditerranée Marseille France

Jean Michel Brunel was graduated from the School of Chemistry of Marseille (France) in 1991. He obtained his Ph.D. degree in 1994 from Université Aix Marseille in the field of asymmetric organophosphorus chemistry. In 1994, he joined the group of Pr. H. B. Kagan (Université Paris Sud) as a postdoctoral fellow working on the enantioselective catalytic oxidation of sulfides. In 1997, he joined the CNRS as Chargé de Recherche and is now working at the Centre de Recherche en Cancérologie de Marseille. His research program is focused on the development of novel classes of antimicrobial and anticancer agents.

lddd_ebm_Tonino-Bucciarelli-ab_001 Bucciarelli Tonino Orcid Department of Oral, Medical and Biotechnological Sciences University of G. d'Annunzio Chieti and Pescara Chieti Italy

Prof. Tonino Bucciarelli is Associate Professor of Biochemistry in the Department of Oral, Medical and Biotechnological Sciences, “G. d’Annunzio” University, Chieti-Pescara, Italy. He graduated in Biological Sciences at the University of L'Aquila Italy (1985), graduated in Medicine and Surgery at the "G. d'Annunzio" University of Chieti-Pescara Italy (2000) and Specialized in Food Science from the University "G. d'Annunzio" Chieti-Pescara Italy (2005). He teaches chemistry and biochemistry courses in the School of Medicine and Surgery. He is the Director of the Spectroscopy and Applied Nanotechnology laboratory. His research interests include glutathione transferase, oxidative stress, nitric oxide synthetase regulation, vitamins, silver nanoparticles with bactericidal and fungicidal action.

lddd_ebm_y-cheng_001 Cheng Y. East China Normal University Shanghai China

Dr. Cheng obtained a doctorate (PhD) in Structural Biology from the University of Science and Technology of China. Currently, Dr. Cheng is a Professor in the School of Life Sciences, East China Normal University. He has published more than 100 papers in journals such as Nature Materials, Nature Communications, J. Am. Chem. Soc. and Angew. Chem. Int. Ed. Dr. Cheng is currently the regional editor of Current Drug Discovery Technologies, and the guest editor of Topics in Current Chemistry. His research focused on drug and gene delivery systems.

lddd_ebm_dai_001 Dai W.M. The Hong Kong University of Science and Technology Hong Kong China

Wei-Min Dai is currently a professor of Chemistry at HKUST. He received a PhD degree from Kyoto University, Japan in 1990, pursued post-doctoral research with Prof. K. C. Nicolaou at Scripps Research Institute at La Jolla during 1990–1992, and then joined HKUST in 1992. Since then, he has focused his research on development of DNA cleavage agents, diversity-oriented synthesis of privileged heterocyclic scaffolds, microwave-assisted organic synthesis, combinatorial synthesis, asymmetric catalysis and enantioselective reactions, diverted total synthesis of complex macrolides, and applications in chemical biology and chemical genetics.

Davis D.R. University of Utah Salt Lake City UT USA lddd_ebm_d-souza_001 De Souza M.V.N. Instituto de Tecnologia em Fàrmacos-Far Manguinhos Rio de Janeiro Brazil

Marcus Vinícius Nora de Souza is a senior technologist at Oswaldo Cruz Foundation – RJ, and leads a research group in organic chemistry, with emphasis on organic synthesis and medicinal chemistry, acting on neglected diseases (tuberculosis and malaria), cancer and synthetic methodologies. He has authored more than 250 manuscripts, 5 patents and 3 books, and their formation includes a PhD in organic and bioorganic chemistry (Universite de Paris XI (Paris-Sud) – France) with stage at the University of Barcelona – Spain, and three postdocs in organic synthesis and medicinal chemistry (University of Florida – USA, Federal University of Juiz de Fora – MG, Pharmaceutical industry Genzyme - Boston – USA).

lddd_ebm_dou_001 Dou Q.P. Wayne State University Detroit MI USA

Dr. Q. Ping Dou is a Professor of Oncology, Pharmacology and Pathology, Barbara Ann Karmanos Cancer Institute, Wayne State University School of Medicine, Detroit, MI. He obtained his B.S. degree in chemistry from Shandong University in 1981, Ph.D. degree in chemistry from Rutgers University in 1988, and postdoctoral training at Dana-Farber Cancer Institute and Harvard Medical School from 1988 to 1993. Dr. Dou has extensive experience in the fields of molecular targeting, drug discovery, chemoprevention, natural products, proteasome inhibitors, cell cycle and apoptosis, and has published ~222 peer-reviewed research and review articles, many of those are included in journals of the highest quality.

lddd_ebm_garattini_001 Garattini E. Instituto di Ricerche Farmacologiche Milan Italy

Dr. Enrico Garattini is a medical doctor and the Head of The Laboratory of Molecular Biology at the IRCCS-Istituto di Ricerche Farmacologiche “Mario Negri” in Milano, Italy, a not-for-profit Institute devoted to experimental and clinical research in the fields of pharmacology and biomedicine. He has over 35 years experience in the area of experimental research and has authored more than 130 articles in “peer-review” journals indexed in PUBMED and a series of book chapters. He has served as expert consultant of the European Agency for the Evaluation of Medicines and the French Institut National de la Santé et de la Recherche Médicale (INSERM). He is also member of the Editorial Board of 4 other scientific journals.

Gueiffier A. UFR des Sciences pharmaceutiques Touirs France Gupta S.P. Meerut Institute of Engineering and Technology Meerut India lddd_ebm_h-litina_001 Hadjipavlou-Litina D. Aristotle University of Thessaloniki Thessaloniki Greece

Professor Dimitra Hadjipavlou-Litina received her undergraduate training in Pharmacy from the Aristotle University of Thessaloniki, Greece (1975-1979) and her PhD in Pharmacy from the same University. She conducted postdoctoral studies at California (supervisor Professor Corwin Hansch). Currently, she is a full professor and a head at the School of Pharmacy. Her research interests involve synthesis and biological studies and the use of Computational Chemistry in Drug Design and resulted in the publication of over 220 peer-reviewed articles over 5000 citations and h factor = 38. Currently, he is the Editor of Current Enzyme Inhibition, CEI and a member of Editorial Advisory Board of “Anti-Inflammatory & Anti-allergy Agents In Medicinal Chemistry” as well as “Cardiovascular & Hematological Agents in Medicinal Chemistry”, “Letters In Drug Design & Discovery”, published by Bentham Science Publishers.

lddd_ebm_heymann_001 Heymann D. Université de Nantes Nantes Cedex France

After his PhD (1995), Dr Heymann successively was appointed: technician, engineer at the Nantes Hospital (FR), Associate-Professor (2001) and Professor of Histology and Embryology at the University of Nantes (2009). He heads an Inserm research laboratory studying the pathogenesis of bone sarcomas. He has authored more than 220 peer-reviewed publications. Since September 2015, He was awarded a personal Chair of Bone Oncology at the University of Sheffield (UK) where He serves as a head of a European Associated Laboratory (Sarcoma Research Unit) Inserm/Univ. Sheffield/Univ. Nantes.

lddd_ebm_h-hong_001 Hong H. National Center for Toxicological Research Jefferson AR USA

Dr. Huixiao Hong is a senior Scientist at National Center for Toxicological Research (NCTR), US Food and Drug Administration (FDA), Arkansas, USA, working on the scientific bases for regulatory application and development of genomics biomarkers. Before joining the FDA, he was the Manager of Bioinformatics Division at Z-Tech, an ICFI company, at NCTR. He held a Research Scientist position at Sumitomo Chemical Company in Japan. He was a visiting scientist at National Cancer Institute (NCI) at National Institutes of Health (NIH). He was also an associate professor and the director of Laboratory of Computational Chemistry at Nanjing University in China. He published more than 160 scientific papers and served as Editor-in-Chief, Executive Editor and Editorial Board member for more than 10 peer-reviewed journals and as reviewer for more than 50 peer-reviewed journals. He received his Ph.D. from Nanjing University in China and did post-doctoral research at Maxwell Institute in Leeds University in England.

lddd_ebm_hsieh_001 Hsieh H.-P. National Health Research Institutes Miaoli Taiwan

Dr. Hiseh is an Associate Director, Institute of Biotechnology and Pharmaceutical Research, National Health Research Institutes and Adjunct Professor at National Tsing Hua University, Taiwan. He has published more than 110 papers in peer reviewed international journals in the area of anti-cancer, anti-diabetics and anti-virus drug discovery and obtained 55 patents granted. Most importantly, DBPR104, invented licensed to SynCore Biotech in 2008, obtained IND approved by US FDA and TFDA in 2010, and currently is undergoing phase II clinical trial in Taiwan. Recently, EGFR inhibitor (DBPR112) also obtained US IND approval in April, 2016 and multiple kinase inhibitor (DBPR114) has been filed for US IND in the first quarter of 2017.

lddd_ebm_kamal-a_001 Kamal A. Jamia Hamdard New Delhi India

Professor Kamal, a Pro Vice Chancellor at Jamia Hamdard, is a distinguished scientist in the field of medicinal chemistry and has been associated with the CSIR-Indian Institute of Chemical Technology as an Outstanding Scientist and with the National Institute of Pharmaceutical Education and Research, Hyderabad as a Project Director. He has won several honours and awards for his research like CSIR Young Scientist Award in Chemical Sciences (1991), Fellow of the National Academy of Sciences, India (1999), Ranbaxy Research Award in the field of Pharmaceutical Sciences (2005), OPPI Scientist Award from the Organization of Pharmaceutical Producers of India (2009), Fellow of the Royal Society of Chemistry, London. His expertise has attracted international academic collaborations with Imperial College London, Kings College London, Greifswald University, University of Cape Town, King Saud University and University of Michigan.

Lam P.Y. Pennsylvania Drug Discovery Institute Doylestown PA USA Linders J.T.M. Johnson & Johnson Pharm. Res. & Develop Beerse Belgium lddd_ebm_marques_001 Marques M.P. University of Coimbra Coimbra Portugal

Maria Paula Marques (October 1960, Portugal) received her MSc in Physical-Chemistry (1987) her PhD (1995) from the University of Coimbra. M.P.M. Marques is currently a professor in the of Life Sciences at the University of Coimbra, assistant-coordinator of the R&D Group “Molecular Physical-Chemistry” and head of the “Chemoprevention, -Therapy & -Toxicology” laboratory. M.P.M. Marques has authored 130 scientific papers, 8 book chapters and co-edited 3 books. She is an affiliated member of the Royal Society of Chemistry and of the Clinical Infrared and Raman Spectroscopy for Medical Diagnosis (CLIRSPEC), the Portuguese delegate for the COST Action Raman4Clinics, an associate editor of RSC Advances and a member of the editorial board of Recent Patents on Anti-Cancer Drug Discovery. Her research is focused on the development of Pt and Pd-based anticancer agents, using vibrational spectroscopy, including neutron techniques and synchrotron-based methods.

lddd_ebm_mcgeary_001 McGeary R. University of Queensland Brisbane Queensland Australia

Dr McGeary is an associate professor in the School of Chemistry and Molecular Biosciences, and an affiliate Associate Professor in the School of Pharmacy at The University of Queensland, Australia. Dr McGeary has authored over 75 publications, as well as 3 book chapters and 11 patents. His research interests encompass the development of new synthetic methodologies, and the design and synthesis of potent inhibitors of metalloenzymes.

lddd_ebm_miguel_001 Munoz M. Virgen del Rocio University Hospital Seville Spain

Dr. Muñoz is M.D. and Ph.D. from the University of Seville, Spain. He has published more than 90 scientific publications and 1 patent. He is a reviewer for more than 50 peer reviewed journals and is a director of 42 PhD thesis. His research is focused on SP/NK-1 receptor and NK-1 receptor antagonists in cancer. Currently, Dr. Muñoz is a principal investigator of the “Research Laboratory in Neuropeptides” (IBIS) Virgen del Rocio University Hospital of Seville, Spain.

lddd_ebm_oka_001 Oka Y. Osaka University Osaka Japan

Dr. Yoshihiro Oka is a physician scientist, and at present a specially appointed professor in the department of Cancer Immunology, Graduate School of Medicine, Osaka University, Japan. He was formerly a Scientific Member of Basel Institute for Immunology, Switzerland, where he studied basic immunology. At Osaka University, Dr. Oka and his colleagues identified cytotoxic T lymphocyte (CTL) epitopes of WT1 protein, which showed that WT1 is a novel cancer antigen. Subsequently, they demonstrated that WT1-targeting immunotherapy, such as WT1 peptide vaccine, has a therapeutic potential for various kinds of malignancies. Dr. Oka’s main interest and research field is cancer immunology and immunotherapy.

lddd_ebm_orhan_001 Orhan I.E. Gazi University Ankara Turkey

Prof. Orhan is a professor of Pharmacognosy and currently dean of Faculty of Pharmacy, Gazi University (Ankara, Turkey). She obtained her Ph.D. degree (2002) from the Department of Pharmacognosy at the same Faculty and holds two Master degrees from Pharmacognosy (1996, Gazi University, Turkey) and Marine Natural Product Chemistry (1998, University of Ryukyus, Japan). Dr. Orhan was a visiting scientist at University of Winnipeg (Canada) in 2003 and served as funding dean of Faculty of Pharmacy at the Eastern Mediterranean University. She has over 180 papers in Science Citation Indexed journals and 13 book chapters and received a number of science awards at national and international levels.

lddd_ebm_pascu_001 Pascu M. Biomedicine and Molecular BioSciences Brussels Belgium

Mihail-Lucian Pascu, PhD., is is a physicist, and senior scientist at the National Institute for Laser, Plasma and Radiation Physics, Bucharest where he heads the Laser Spectroscopy Group, he founded in 1975. He is Professor in the Physics Faculty, University of Bucharest where he supervises PhDs. His interests are laser physics, tunable lasers, spectroscopy, optofluidics, biophotonics and biomedicine. He has published over 200 papers, several book/or book chapters on lasers in biophotonics and biomedicine and presented over 300 communications at international conferences. He was Scientific Officer at European Commission-DG-RTD and European Science Foundation serving COST Office between 2001 and 2006.

lddd_ebm_pirotte_001 Pirotte B. University of Liège Liege Belgium

Bernard Pirotte is a pharmacist by education (Université de Liège, Belgium, 1981). He received the Ph.D. degree in 1989 (Ph.D. thesis in medicinal chemistry) and the Agrégation de l’Enseignement Supérieur degree in 2001 from the same university. He worked as an F.N.R.S. researcher between 1990 and 2002 and became a Professor at the University of Liège in 2002 (currently, Full Professor in Medicinal Chemistry). His main fields of interest are the design and synthesis of new ion channel modulators, positive allosteric modulators of ionotropic glutamate receptors, anticancer drugs, innovative approaches in the identification of new drug targets (metabolomics, GPCR deorphanization).

lddd_ebm_polanski_001 Polanski J. University of Silesia Katowice Poland

Dr. Polanski obtained his PhD from the University of Silesia, Katowice, Poland. Dr Polanski also holds a habilitation in organic and medicinal chemistry from the Lodz University of Technology, Lodz, Poland. Currently Dr. Polanski is a Full Professor in the University of Silesia, Katowice, Poland. He has published more than 100 scientific publications and is a named inventor of 20 issued patents. He is a member of the editorial board of Combinatorial Chemistry and HTS (Bentham).

lddd_ebm_robak_001 Robak T. Medical University of Lodz Lodz Poland

Tadeusz Robak MD., Ph.D. is a Professor of Hematology at the Medical University of Lodz, Poland. He currently holds the posts of Professor of Hematology at the Medical University of Lodz and Chief of Department of Hematology at the Copernicus Memorial Hospital in Lodz, Poland. The particular research emphasis has been on the application of new drugs in the treatment of leukemia multiple myeloma and lymphoma and interactions of antineoplastic agents. Professor Robak has published more than 550 journal articles, 480 abstracts and 25 books and chapters. He received “Eminent Scientist of the Year 2010” award from International Research Promotion Council (IRPC).

lddd_ebm_romagnoli_001 Romagnoli R. University of Ferrara Ferrara Italy

Romeo Romagnoli graduated in Pharmaceutical Chemistry and Technology from the University of Ferrara in 1990 and in 1995 he received his Ph.D. in Organic Chemistry. From 1999 to 2014, he was Assistant Professor in the department of Pharmaceutical Chemistry at the University of Ferrara.. His scientific interests have focused on new synthetic methods for the preparation of natural substances or biologically active analogues, the medicinal chemistry of ligands for adenosine receptors subtypes and antitumor agents. He has published more than 230 research papers and 20 international patents.

lddd_ebm_roy_001 Roy K. Jadavpur University Kolkata India

Dr. Kunal Roy is a Professor in the Department of Pharmaceutical Technology, Jadavpur University, Kolkata, India. He has been a recipient of Commonwealth Academic Staff Fellowship (University of Manchester, 2007) and Marie Curie International Fellowship (University of Manchester, 2013). The field of his research interest is QSAR and Molecular Modeling with application in Drug Design and Predictive Toxicology. Dr. Roy has published more than 250 research articles in peer reviewed journals and coauthored/edited several QSAR related books ( https://sites.google.com/site/kunalroyindia/home/krlistofpublications ). His current h-index is 33. Dr. Roy has been recently recognized as one of the Top Ten Authors in the list of Active Indian Researchers (2009-14) in the subjects of Chemistry, and Pharmacology, Toxicology & Pharmaceutics in the Bibliometric Analysis published by DST, Govt of India (available from http://www.dst.gov.in/sites/default/files/Elsevier.pdf).

Skiba M. UFR Médecine & Pharmacie Rouen France Soriano D.S. University of Pittsburgh-Bradford Bradford PA USA lddd_ebm_toninello_001 Toninello A. Università degli Studi di Padova Padova Italy

Prof. Antonio Toninello obtained his degree in Biological Sciences from the University of Padova, Italy. He was Associate Professor at the Faculty of Natural, Physical, and Mathematical Sciences, University of Padova and Italian Member of Cost Actions on Biogenically Active Amines in Food andHealth Implications of Dietary Amines. At present is Senior Scientist of Patavinum Studio at the Department of Biomedical Sciences, University of Padova.

Prof. Toninello is author of more than 150 scientific publications in the most important international biochemical journals .

Valko M. Slovak Technical University Bratislava Slovak Republic lddd_ebm_yamagishi_001 Yamagishi S.-I. Kurume University School of Medicine Kurume Japan

Sho-ichi Yamagishi, MD, PhD is a Professor and Chairman of Department of Pathophysiology and Therapeutics of Diabetic Vascular Complications, Kurume University School of Medicine, Japan. He has received a PhD from Kanazawa University, Japan in 1993. He received Angiogenesis Stem Cell Award from AHA in 2003, Distinguished Investigator Award from Japan Diabetes Society in 2005, and Research Award from Japanese Society of Anti-Aging Medicine in 2012. He is serving as an editorial board member of reputed journals and published more than 500 research papers, including Nature, JCI, JACC, JASN, Diabetes, Diabetes Care, and FASEB J. His research interest is Diabetes, Cardiology, Aging, Glycation and Oxidative Stress..

lddd_ebm_g-f-yang_001 Yang G.-F. College of Chemistry Central China Normal University Wuhan China

Guang-Fu Yang got his Doctor of Philosophy in Pesticide Science from Institute of Element-Organic Chemistry, Nankai University in 1997. After that, he joined in CCNU and became a full professor four years later. He served as the dean of the College of Chemistry of CCNU from 2002 to 2014, and then was promoted to be the Assistant President of Central China Normal University in February 2014. He has over 20 years of working on the area of rational design and syntheses of biologically active small molecules (drug and pesticide) and their chemical biology. He was awarded in 2009 the National foundation for distinguish young scientist from National Nature Science Foundation of China. He has published around 200 peer-reviewed papers, 25 patents and 8 book chapters.

Associate Editorial Board Member lddd_ebm_bonomo-mg-ah_001 Bonomo M.G. Università degli Studi della Basilicata Potenza Italy

Dr. Maria Grazia Bonomo is a biologist and holds a class honours degree in Biological Sciences and has completed her PhD in Biology and Biotechnologies from University of Basilicata, Italy. She is a professor of teaching ‘Physiology and Genetics of Microorganisms’ for the Degree Course in Biotechnologies and she has a post-doc fellowship at University of Basilicata and performs supplementary teaching activities for the course of General and Applied Microbiology. She is author/co-author of many international papers and an editorial board member and/or reviewer of reputed journals..

lddd_ebm_rizzuti_001 Rizzuti B. National Council of Research Cosenza Italy

Dr. Bruno Rizzuti is a research scientist at the National Research Council of Italy, presently working within the Institute of Nanotechnology. He is a theoretical biophysicist, and received his PhD in Physics from the University of Calabria. His research interests include the study of the folding, binding and aggregation properties of proteins, for applications in nanomedicine and 'in silico' biopharmaceutics. In particular, he is currently involved in several projects focused on computer-aided drug discovery, development, design and selection.

Executive Guest Editor(s) lddd_ebm_Liu_001 Liu Xiaobo Environmental Engineering Program Guangdong Technion-Israel Institute of Technology Shantou China

Dr. Xiaobo Liu is a professor of microbiology in the School of Environmental and Biological Engineering, Nanjing University of Science and Technology, Nanjing, China. He received his PhD degree in Microbial Molecular Ecology from The University of Hong Kong and had a visiting research in biofilm biotechnology in Dr. Bin Cao’s lab at Singapore Centre for Environmental Life Sciences Engineering (SCELSE), Nanyang Technological University, Singapore. He also worked as a research fellow at Guangdong Technion-Israel Institute of Technology (GTIIT). His research experience covers the fields of environmental microbiology, biodeterioration, biofilm control, biocatalysis for biosynthesis and biodegradation, and microbial electrochemistry. His research interests focus on understanding the signals and processes that promote biofilm formation, with the aim of developing new strategies for tackling biofilm-related industrial and environmental problems, including fouling or contamination of microorganisms inside food industrial pipelines, biofilm-mediated biodeterioration of materials, and biofilm-based catalysis for biotechnological applications.

xbliu123@connect.hku.hk xiaobo.liu@gtiit.edu.cn
lddd_ebm_Guo_001 Guo Dawei Engineering Center of Innovative Veterinary Drugs Nanjing Agricultural University Nanjing China gdawei0123@njau.edu.cn
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