Letters in Drug Design & Discovery

ISSN (Print): 1570-1808
ISSN (Online): 1875-628X

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Volume 20, Issue 6

Letter Article

Design and Synthesis of an Hsp90 and HDAC Dual Inhibitor as Antitumor Agent

Pp: 619-627
Author(s): Jiyong Wu, Dongbo Wang, Jing Nie, Di Zhang, Lei Sun, Shifeng Kan and Wei Xu*
DOI: 10.2174/1570180819666220530145951

Research Article

In-Silico and In-Vitro Screening of Novel Pyridazine Analogs as Muscle Relaxant Agent on Acetylcholine Muscarinic Receptor

Pp: 628-638
Author(s): Aamir Malik, Rakhi Mishra*, Rupa Mazumder, Avijit Mazumder and Ketki Garg
DOI: 10.2174/1570180819666220429154430

Research Article

Acenaphthotriazine Thio-triazole Derivatives as Anti-cancer Agents Triggering Cell Cycle Arrest in Breast Cancer Cells

Pp: 639-648
Author(s): Aida Iraji, Nasim Shahrokh, Omidreza Firuzi, Maryam Mohabbati, Ramin Miri, Hossein Sadeghpour, Mehdi Khoshneviszadeh* and Najmeh Edraki*
DOI: 10.2174/1570180819666220425123016

Research Article

Iodinated Curcumin as a Novel Anti-bacterial Agent to Combat Methicillin- resistant Staphylococcus aureus in Bovine Mastitis: In Silico Analysis, Synthesis and In Vitro Evaluation

Pp: 649-661
Author(s): Atul Morya, Monika Chaudhary, Netra Prasad Neupane, Amita Verma, Rupinder Kaur Sodhi, Dharmendra Kumar Khatri and Jitender Madan*
DOI: 10.2174/1570180819666220510125842

Research Article

In-silico Identification and Analysis of Hub Proteins for Designing Novel First-Line Anti-seizure Medications

Pp: 662-673
Author(s): Pawan Kumar, Deepak Sheokand, Vandana Saini and Ajit Kumar*
DOI: 10.2174/1570180819666220512122511

Research Article

QSAR Study on the Antitumor Activity of Novel 1,2, 3-Triazole Compounds Based on Topomer Comfa Method

Pp: 674-683
Author(s): Qiu Lie Wei, Zhang Xing and Tong Jian Bo*
DOI: 10.2174/1570180819666220512123310

Research Article

Bioinformatic Screening of Compounds from Iranian Lamiaceae Family Members Against SARS-CoV-2 Spike Protein

Pp: 684-698
Author(s): Abbas Alibakhshi*, Shima Gharibi, Shahrzad Ahangarzadeh* and Fatemeh Yarian
DOI: 10.2174/1570180819666220509090514

Research Article

QSAR and DFT Studies of Some Tacrine-Hydroxamate Derivatives as Inhibitors of Cholinesterase (AChEs) in the Treatment of Alzheimer's Disease

Pp: 699-712
Author(s): Imad Hammoudan, Samir Chtita*, Ossama Daoui, Souad Elkhattabi, Mohamed Bakhouch, Mohamed El Yazidi, Farhan Siddique and Driss Riffi-Temsamani
DOI: 10.2174/1570180819666220512174409

Research Article

Investigation of Therapeutic Drug Monitoring of Tacrolimus in Different Age Groups: Results from a Turkish Nationwide Study

Pp: 718-723
Author(s): Murat Caglayan*, Ataman Gonel, Osman Celik, Abdulvahit Sozuer, Mustafa Mahir Ulgu, Naim Ata and Suayip Birinci
DOI: 10.2174/1570180819666220825122534

Research Article

Synthesis, Docking Studies, and Biological Evaluation of Betti Bases as Promising Anti-tubercular Agents

Pp: 724-737
Author(s): Poornima Acharya, Mucheli Muni Venkata Ramana*, Nilesh Korgavkar, Ganesh Pavale and Manish Upadhyay
DOI: 10.2174/1570180819666220520141039

Research Article

Antimicrobial Activity and Metabolite Fingerprinting of a Microcolonial Fungal Isolate TD-082 from the Arid Thar Desert, India

Pp: 738-744
Author(s): Nidhi Srivastava, Shivangi Gupta, Bhawna Bhatt, Paresh Sharma, Ahongshangbam Ibeyaima and Indira P. Sarethy*
DOI: 10.2174/1570180819666220509100537

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