Volume 20, Issue 6
Design and Synthesis of an Hsp90 and HDAC Dual Inhibitor as Antitumor Agent
Pp: 619-627
Author(s): Jiyong Wu, Dongbo Wang, Jing Nie, Di Zhang, Lei Sun, Shifeng Kan and Wei Xu*
DOI: 10.2174/1570180819666220530145951
In-Silico and In-Vitro Screening of Novel Pyridazine Analogs as Muscle Relaxant Agent on Acetylcholine Muscarinic Receptor
Pp: 628-638
Author(s): Aamir Malik, Rakhi Mishra*, Rupa Mazumder, Avijit Mazumder and Ketki Garg
DOI: 10.2174/1570180819666220429154430
Acenaphthotriazine Thio-triazole Derivatives as Anti-cancer Agents Triggering Cell Cycle Arrest in Breast Cancer Cells
Pp: 639-648
Author(s): Aida Iraji, Nasim Shahrokh, Omidreza Firuzi, Maryam Mohabbati, Ramin Miri, Hossein Sadeghpour, Mehdi Khoshneviszadeh* and Najmeh Edraki*
DOI: 10.2174/1570180819666220425123016
Iodinated Curcumin as a Novel Anti-bacterial Agent to Combat Methicillin- resistant Staphylococcus aureus in Bovine Mastitis: In Silico Analysis, Synthesis and In Vitro Evaluation
Pp: 649-661
Author(s): Atul Morya, Monika Chaudhary, Netra Prasad Neupane, Amita Verma, Rupinder Kaur Sodhi, Dharmendra Kumar Khatri and Jitender Madan*
DOI: 10.2174/1570180819666220510125842
In-silico Identification and Analysis of Hub Proteins for Designing Novel First-Line Anti-seizure Medications
Pp: 662-673
Author(s): Pawan Kumar, Deepak Sheokand, Vandana Saini and Ajit Kumar*
DOI: 10.2174/1570180819666220512122511
QSAR Study on the Antitumor Activity of Novel 1,2, 3-Triazole Compounds Based on Topomer Comfa Method
Pp: 674-683
Author(s): Qiu Lie Wei, Zhang Xing and Tong Jian Bo*
DOI: 10.2174/1570180819666220512123310
Bioinformatic Screening of Compounds from Iranian Lamiaceae Family Members Against SARS-CoV-2 Spike Protein
Pp: 684-698
Author(s): Abbas Alibakhshi*, Shima Gharibi, Shahrzad Ahangarzadeh* and Fatemeh Yarian
DOI: 10.2174/1570180819666220509090514
QSAR and DFT Studies of Some Tacrine-Hydroxamate Derivatives as Inhibitors of Cholinesterase (AChEs) in the Treatment of Alzheimer's Disease
Pp: 699-712
Author(s): Imad Hammoudan, Samir Chtita*, Ossama Daoui, Souad Elkhattabi, Mohamed Bakhouch, Mohamed El Yazidi, Farhan Siddique and Driss Riffi-Temsamani
DOI: 10.2174/1570180819666220512174409
Experimental Investigation of Immunoglobulin and Complement Concentrations in Exposure to IVIG, HBIG, Rituximab, Tocilizumab, and Bevacizumab
Pp: 713-717
Author(s): Murat Caglayan* and Ataman Gonel
DOI: 10.2174/1570180819666220804105533
Investigation of Therapeutic Drug Monitoring of Tacrolimus in Different Age Groups: Results from a Turkish Nationwide Study
Pp: 718-723
Author(s): Murat Caglayan*, Ataman Gonel, Osman Celik, Abdulvahit Sozuer, Mustafa Mahir Ulgu, Naim Ata and Suayip Birinci
DOI: 10.2174/1570180819666220825122534
Synthesis, Docking Studies, and Biological Evaluation of Betti Bases as Promising Anti-tubercular Agents
Pp: 724-737
Author(s): Poornima Acharya, Mucheli Muni Venkata Ramana*, Nilesh Korgavkar, Ganesh Pavale and Manish Upadhyay
DOI: 10.2174/1570180819666220520141039
Antimicrobial Activity and Metabolite Fingerprinting of a Microcolonial Fungal Isolate TD-082 from the Arid Thar Desert, India
Pp: 738-744
Author(s): Nidhi Srivastava, Shivangi Gupta, Bhawna Bhatt, Paresh Sharma, Ahongshangbam Ibeyaima and Indira P. Sarethy*
DOI: 10.2174/1570180819666220509100537
Molecular Docking Simulation-Based Pharmacophore Modeling to Design Translation Inhibitors Targeting c-di-GMP Riboswitch of Vibrio cholera
Pp: 745-754
Author(s): Somdutt Mujwar* and Kamalraj Pardasani
DOI: 10.2174/1570180819666220516123249
Microwave-assisted Synthesis and Characterization of Acrylamide Grafted Copolymer of Okra Gum with the Application of 32 Central Composite Designs (CCD)
Pp: 755-766
Author(s): Anshul Attri, Mohamad Taleuzzaman and Surajpal Verma*
DOI: 10.2174/1570180819666220517084707
Mentha longifolia ssp. longifolia Essential Oil Components as Novel Carbonic Anhydrase Isoform II and IX Inhibitors: Biological and Molecular Docking Studies
Pp: 767-778
Author(s): Ayça Aktaş Karaçelik* and Gözde Yalçın Özkat
DOI: 10.2174/1570180819666220510144912
Optimization of Pharmacophore of Novel Hybrid Nucleus of 1,3,4- oxadiazole-chalcone Using Literature Findings and In-silico Approach as EGFR Inhibitor
Pp: 779-791
Author(s): Shital M. Patil* and Shashikant V. Bhandari
DOI: 10.2174/1570180819666220414102310