Frontiers in Cancer Immunology

Volume: 2

Signal Transduction Molecules and Pathways in Cancer: Implication of the Immune System in Modulating Cancer Development and Progression

Author(s): Mahbuba Rahman

Pp: 69-85 (17)

Doi: 10.2174/9781681083070116020005

* (Excluding Mailing and Handling)

Abstract

Signal transduction pathways and associated molecules play important role in maintaining cell death and cell survival. However, in cancer cells, some of these molecules are mutated and lead to cancer progression. These molecules also interfere with the components of the humoral and the cell mediated immune systems in tumor environment. Therefore, identifying these can be potential targets for cancer treatment.


Keywords: Apoptosis, Autophagy, JAK-STAT, K-ras, Myc, p53, Signal transduction pathways.

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