Omics Technologies for Clinical Diagnosis and Gene Therapy: Medical Applications in Human Genetics

Multi-omics Data Integration: Applications in Systems Genomics

Author(s): Anam Naz*, Ammara Siddique, Aqsa Ikram, Bisma Rauff, Huma Tariq and Sajjad Ahmed

Pp: 137-155 (19)

Doi: 10.2174/9789815079517122010012

* (Excluding Mailing and Handling)


Interpretation of molecular differences and intricacy at multiple stages, for instance proteome, genome, epigenome, metabolome, and transcriptome is needed for a thorough understanding of disease and human health. Biology has been reliant on data produced at these stages, which is collectively referred to as multi-omics data, after the emergence of sequencing techniques. Among all the aspects of biology, rapid development in high-throughput data initiation has enabled to carry out research on multi-omics systems biology. Metabolomics, proteomics, and transcriptomics data can provide answers to the targeted biological queries about the expression of metabolites, proteins, and transcripts, independently. A concise summary of multi-omics data sources, challenges in datasets integration, and visualization portals is also discussed.

Keywords: Genomics, Metabolomics, Proteomics, Transcriptomics, Omics.

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