Potential Antimicrobial Activities of Terpenoids

The antimicrobial effect of essential oils and their main constituents, the terpenoids, has been generally reviewed in this article, with a comparative investigation of the structure-activity relationship. Terpenoids are widespread metabolites in plants belonging to different chemical classes, whereas oxygenated derivatives constitute the predominates. They could be classified as diterpenes, triterpenes, tetraterpenes, or hemiterpenes and sesquiterpenes. As crude materials, terpenoids are also broadly utilized in drug, food, and beauty care product ventures. Terpenoids have antitumor, anti-inflammatory, antibacterial, antiviral, antimalarial effects, promote transdermal absorption, prevent and treat cardiovascular diseases, and hypoglycemic activities. Moreover, terpenoids have many critical uses as insecticides, immunoregulators, antioxidants, antiaging, and neuroprotection agents. Terpenoids have a complicated construction with assorted impacts and various components of activity. Using plants – containing – terpenoids as neutraceuticals in the nutrition of humans and animals also constitutes a potential issue as natural inhibitors for microbes. These phytochemicals are generally conveyed in soil products and are particularly helpful in food protection as microbial development inhibitors. 

Keywords: Terpenoids, Essential oils, Antimicrobial activities, Mode of action, Progress of research.