Surface Enhanced Raman Spectroscopy: Biosensing and Diagnostic Technique for Healthcare Applications

Smartphone Based Biosensors on Lateral Flow Assay Coupled to SERS: Point-of-Care Applications

Author(s): Rajasekhar Chokkareddy, Suvardhan Kanchi*, Surendra Thakur and Venkatasubba Naidu Nuthalapati * .

Pp: 191-212 (22)

DOI: 10.2174/9789815039115121010010

* (Excluding Mailing and Handling)

Abstract

Point-of-care (POC) diagnostic analysis is a fast rising arena that goals to
improve the rapidness, low-cost, sensitive and selective in-vitro diagnostic analysis
platforms that are independent, moveable, and can be used everywhere from current
clinics to isolated and low resource regions. In addition, surface enhanced Raman
spectroscopy (SERS) offers a suitable sensory stage whereby objective particles at
smaller concentration are recognized, potentially identifying a particular substances.
There are some analytical methods which can induce motivated Raman scattering,
significantly attractive the possibility of Raman scattering, but most of these
procedures need ultra-fast tunable lasers and microscopy set-ups making them
impossible for most users. SERS exploits surface plasmons to improve Raman
scattering by numerous orders of magnitude, without lacking various equipment than
traditional Raman spectroscopy. As a result, SERS has been extensively useful in a
selection of research activities using various substrates, one of which is a smartphone
based biosensors. In outlining the development of SERS methods over the past few
years joined with new expansions in smartphone based biosensors, metal and metal
oxide nanomaterials, low-cost paper diagnostics, and high-quantity of microfluidics, a
wide-ranging number of novel potentials display the possible for decoding SERS
biosensors to the POC.


Keywords: Lateral Flow-assay, Point-of-care Application, Smartphone, Surface Enhanced Raman Spectroscopy.

Related Journals
Related Books
© 2024 Bentham Science Publishers | Privacy Policy