Phytotherapy in the Management of Diabetes and Hypertension

Volume: 3

Chrysophyllum Cainito L.

Author(s): A. Sánchez-Recillas, L. Cerón-Romero, R. Ortiz-Andrade and J.C. Sánchez-Salgado

Pp: 189-210 (22)

Doi: 10.2174/9789811459139120030009

* (Excluding Mailing and Handling)


Chrysophyllum cainito L. is part of the family Sapotaceae and native to the Greater Antilles and the West Indies. This specie is a medicinal plant used around the world by many cultures, commonly known as “star apple” or “caimito”. Some studies have reported that C. cainito possesses many pharmacological properties as antidiabetic, anti-hypersensitivity, antihypertensive, anti-inflammatory, antimicrobial, antinociceptive, antioxidant, gastroprotective and immunosuppressive. Also, phytochemical evidence has revealed that the main secondary metabolites in C. cainito are alkaloids, tannins, flavonoids, phenols, sterols, coumarins and triterpenes which are responsible for their pharmacological benefits. In vitro and in vivo toxicology studies have suggested human consumption of Chrysophyllum cainito leaves as safe. This chapter includes scientific information of pharmacology, toxicology and phytochemistry of C. cainito seeds, leaves, and fruits with the purpose to contribute valuable scientific information to future research in drug development based on C. cainito as a source of raw material.

Keywords: Antidiabetic, Anti-inflammatory, Antimicrobial, Antinociceptive, Antioxidant, Chrysophyllum cainito L., Immunosuppressive, Medicinal use, Pharmacology Phytochemicals, Toxicity.

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