In this chapter, we thoroughly review the current developments and challenges in the field of tissue engineering of normal and breast cancer cells. We also briefly describe the current advances in cell culture techniques and common biomaterials, which are useful in the field of tissue engineering. Further, the need for a new microencapsulation technology of cells utilizing the microfluidic method is illustrated. Moreover, the most recent applications of cell-laden microcapsules in tissue engineering are summarized. Lastly, the chapter is concluded with an outline of the future prospective.