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ACUTE MYELOID LEUKEMIA (AML)
Results 1 - 70 of 70
Understanding Unmet Needs in the Older Acute Myeloid Leukemia (AML) Patient

Journal: Current Cancer Therapy Reviews
Volume: 12,Issue: 4
Page: 246-252
Authors: Pablo Loarte, Irina Dashkova, Leanne Tortez, Anna Dashkova, Andrzej Kozikowski, Ramy Ibrahim and Renee Pekmezaris

Proteomic Strategies for Individualizing Therapy of Acute MyeloidLeukemia (AML)

Journal: Current Pharmaceutical Biotechnology
Volume: 7,Issue: 3
Page: 159-170
Authors: Gry Sjoholt, Siv Lise Bedringaas, Anne P. Doskeland and Bjorn Tore Gjertse

The Phosphoinositide 3-Kinase (PI3K)/AKT Signaling Pathway as a Therapeutic Target for the Treatment of Human Acute Myeloid Leukemia (AML)

Journal: Current Signal Transduction Therapy
Volume: 2,Issue: 3
Page: 246-256
Authors: Alberto M. Martelli, Giovanna Tabellini, Roberta Bortul, Maria Nyakern, Pier Luigi Tazzari, Camilla Evangelisti and Lucio Cocco

Poly (D,L-lactic-co-glycolide) Nanoparticles for the Improved Therapeutic Efficacy of All-trans-retinoic Acid: A Study of Acute Myeloid Leukemia (AML) Cell Differentiation In Vitro

Journal: Medicinal Chemistry
Volume: 8,Issue: 5
Page: 805-810
Authors: Aswathy Mary Simon, Sankar Jagadeeshan, Emimol Abraham, Ashalatha Akhilandeshwaran, Jisha J. Pillai, Nisha Asok Kumar, Asha Nair Sivakumari and Gopalakrishnapillai Sankaramangalam Vinod Kumar

Immunomodulatory Drugs: IMiDs in Acute Myeloid Leukemia (AML)

Journal: Current Drug Targets
Volume: 18,Issue: 3
Page: 304-314
Authors: Joshua F. Zeidner and Matthew C. Foster

Potential Therapeutic Approaches for the Treatment of Acute Myeloid Leukemia with AML1-ETO Translocation

Journal: Current Cancer Drug Targets
Volume: 16,Issue: 3
Page: 215-225
Authors: Rashi Arora, Sharad Sawney and Daman Saluja

Small Molecule FLT3 Tyrosine Kinase Inhibitors

Journal: Current Pharmaceutical Design
Volume: 10,Issue: 11
Page: 1183-1193
Authors: Mark Levis and Donald Small

Implication of microRNAs in the Pathogenesis of MDS

Journal: Current Pharmaceutical Design
Volume: 18,Issue: 22
Page: 3170-3179
Authors: Jing Fang, Melinda Varney and Daniel T. Starczynowski

Oncogenic Signaling in Acute Myeloid Leukemia

Journal: Current Drug Targets
Volume: 8,Issue: 2
Page: 237-246
Authors: Christian H. Brandts, Wolfgang E. Berdel and Hubert Serve

Novel and Emerging Drugs for Acute Myeloid Leukemia

Journal: Current Cancer Drug Targets
Volume: 12,Issue: 5
Page: 522-530
Authors: E. M. Stein and M. S. Tallman

Screening for Marine Natural Products with Potential as Chemotherapeutics for Acute Myeloid Leukemia

Journal: Current Pharmaceutical Biotechnology
Volume: 17,Issue: 1
Page: 71-77
Authors: Espen Hansen and Jeanette H. Andersen

Signal transduction in Acute Myeloid Leukemia – Implications for Novel Therapeutic Concepts.

Journal: Current Cancer Drug Targets
Volume: 15,Issue: 9
Page: 803-821
Authors: Heiko Konig and Cedric Dos Santos

Proteomics of p53 in Diagnostics and Therapy of Acute Myeloid Leukemia

Journal: Current Pharmaceutical Biotechnology
Volume: 7,Issue: 3
Page: 199-207
Authors: Nina Anensen, Ingvild Haaland, Clive D'Santos, Werner Van Belle and Bjorn Tore Gjertsen

Induction of Apoptosis via the Modulation of Reactive Oxygen Species (ROS) Production in the Treatment of Myeloid Leukemia

Journal: Current Pharmaceutical Biotechnology
Volume: 7,Issue: 5
Page: 323-329
Authors: Masahiro Kizaki, Mingji Xian, Morihiko Sagawa and Yasuo Ikeda

Vascular Endothelial Growth Factor and Its Receptor as Drug Targets in Hematological Malignancies

Journal: Current Drug Targets
Volume: 8,Issue: 2
Page: 257-268
Authors: Torsten Kessler, Frauke Fehrmann, Ralf Bieker, Wolfgang E. Berdel and Rolf M. Mesters

Signaling Through RAS-RAF-MEK-ERK: from Basics to Bedside

Journal: Current Medicinal Chemistry
Volume: 14,Issue: 5
Page: 601-623
Authors: Armin Zebisch, Armin P. Czernilofsky, Gyorgy Keri, Julja Smigelskaite, Heinz Sill and Jakob Troppmair

Microarray-Based Identification of New Targets for Specific Therapies in Pediatric Leukemia

Journal: Current Drug Targets
Volume: 8,Issue: 6
Page: 761-764
Authors: Monique L. den Boer and Rob Pieters

Liposomal-All-trans-Retinoic Acid in the Treatment of Acute Promyelocytic Leukemia

Journal: Current Cancer Therapy Reviews
Volume: 1,Issue: 3
Page: 239-250
Authors: Bulent Ozpolat, Maribel Tirado-Gomez and Gabriel Lopez-Berestein

Antiangiogenic Therapy in Hematologic Malignancies

Journal: Current Pharmaceutical Design
Volume: 10,Issue: 11
Page: 1221-1234
Authors: Moehler T. M., Hillengass J., Goldschmidt H. and Ho A. D.

Inhibition of Raf Kinase in the Treatment of Acute Myeloid Leukemia

Journal: Current Pharmaceutical Design
Volume: 8,Issue: 25
Page: 2243-2248
Authors: Michael Crump

Immunotherapy of Acute Myeloid Leukemia

Journal: Current Pharmaceutical Biotechnology
Volume: 2,Issue: 3
Page: 209-215
Authors: Arthur E. Frankel, Maria R. Baer, Donna E. Hogge and Robert K. Stuart

Global Gene Expression in Classification, Pathogenetic Understanding and Identification of Therapeutic Targets in Acute Myeloid Leukemia

Journal: Current Pharmaceutical Biotechnology
Volume: 8,Issue: 6
Page: 344-354
Authors: Anne Margrete Oyan, Trond Hellem Bo, Inge Jonassen, Elling Ulvestad, Bjorn Tore Gjertsen, Oystein Bruserud and Karl-Henning Kalland

Targeting the Acute Myeloid Leukemia Stem Cells

Journal: Anti-Cancer Agents in Medicinal Chemistry
Volume: 10,Issue: 2
Page: 104-110
Authors: Alexandre Krause, Luciana M. Fontanari Krause and Eduardo M. Rego

Combination Therapy with Arsenic Trioxide for Hematological Malignancies

Journal: Anti-Cancer Agents in Medicinal Chemistry
Volume: 10,Issue: 6
Page: 504-510
Authors: Shinichiro Takahashi

Stem Cell Transplantation in Pediatric Leukemia and Myelodysplasia: State of the Art and Current Challenges

Journal: Current Stem Cell Research & Therapy
Volume: 2,Issue: 1
Page: 53-63
Authors: Marc Bierings, James B. Nachman, C. Michel Zwaan and James B. Nachman

Implications of FLT3 Mutations in the Therapy of Acute Myeloid Leukemia

Journal: Reviews on Recent Clinical Trials
Volume: 2,Issue: 2
Page: 135-141
Authors: Ryan J. Mattison, Kelly R. Ostler, Frederick L. Locke and Lucy A. Godley

New Treatment Approaches in Acute Myeloid Leukemia: Review of Recent Clinical Studies

Journal: Reviews on Recent Clinical Trials
Volume: 7,Issue: 3
Page: 224-237
Authors: Kelly Norsworthy, Leo Luznik and Ivana Gojo

Pharmacokinetic and Pharmacogenetic Analysis of Oral Busulfan in Stem Cell Transplantation: Prediction of Poor Drug Metabolism to Prevent Drug Toxicity

Journal: Current Drug Safety
Volume: 7,Issue: 3
Page: 211-217
Authors: Norberto Krivoy, Tsila Zuckerman, Hela Elkin, Lia Froymovich, Jacob M. Rowe and Edna Efrati

Innovative Cell Therapy in the Treatment of Serious Adverse Events Related to Both Chemo-Radiotherapy Protocol and Acute Myeloid Leukemia Syndrome: The Infusion of Mesenchymal Stem Cells Post-Treatment Reduces Hematopoietic Toxicity and Promotes Hematopoietic Reconstitution

Journal: Current Pharmaceutical Biotechnology
Volume: 14,Issue: 9
Page: 842-848
Authors: Loic Fouillard, Sabine Francois, Sandrine Bouchet, Morad Bensidhoum, Abdelatif Elm’selmi and Alain Chapel

A New Strategy to Target Acute Myeloid Leukemia Stem and Progenitor Cells Using Chidamide, a Histone Deacetylase Inhibitor

Journal: Current Cancer Drug Targets
Volume: 15,Issue: 6
Page: 493-503
Authors: Yin Li, Kai Chen, Yong Zhou, Yiren Xiao, Manman Deng, Zhiwu Jiang, Wei Ye, Xiangmeng Wang, Xinru Wei, Jie Li, Jiabao Liang, Zhongxin Zheng, Yao Yao, Weiguang Wang, Peng Li and Bing Xu

Global Cell Proteome Profiling, Phospho-signaling and Quantitative Proteomics for Identification of New Biomarkers in Acute Myeloid Leukemia Patients

Journal: Current Pharmaceutical Biotechnology
Volume: 17,Issue: 1
Page: 52-70
Authors: Elise Aasebø, Rakel B. Forthun, Frode Berven, Frode Selheim and Maria Hernandez-Valladares

The Past, Present and Future Subclassification of Patients with Acute Myeloid Leukemia

Journal: Current Pharmaceutical Biotechnology
Volume: 17,Issue: 1
Page: 6-19
Authors: Rakel B. Forthun, Carina Hinrichs, Tara H. Dowling, Øystein Bruserud and Frode Selheim

Development of personalized molecular therapy for acute myeloid leukemia

Journal: Current Pharmaceutical Biotechnology
Volume: 17,Issue: 1
Page: 20-29
Authors: Caroline B.N. Engen, Ehsan Hajjar and Bjørn T. Gjertsen

Clinical Impact of Hypomethylating Agents in the Treatment of Myelodysplastic Syndromes

Journal: Current Pharmaceutical Design
Volume: 22,Issue: 16
Page: 2349-2357
Authors: Carlo Finelli, Matilde Y. Follo, Marta Stanzani, Sarah Parisi, Cristina Clissa, Sara Mongiorgi, Marilena Barraco and Lucio Cocco

Epigenetics and Adult Acute Myeloid Leukemia

Journal: Current Pharmacogenomics and Personalized Medicine
Volume: 13,Issue: 2
Page: 117-133
Authors: Maël Heiblig, Mohamed El Hamri, Gilles Salles and Xavier Thomas

Pyrimethamine as a Potent and Selective Inhibitor of Acute Myeloid Leukemia Identified by High-throughput Drug Screening

Journal: Current Cancer Drug Targets
Volume: 16,Issue: 9
Page: 818-828
Authors: Amit Sharma, Nidhi Jyotsana, Courteney K. Lai, Anuhar Chaturvedi, Razif Gabdoulline, Kerstin Görlich, Cecilia Murphy, Jan E. Blanchard, Arnold Ganser, Eric Brown, John A. Hassell, R. Keith Humphries, Michael Morgan and Michael Heuser

Novel Antigen Targets for Immunotherapy of Acute Myeloid Leukemia

Journal: Current Drug Targets
Volume: 18,Issue: 3
Page: 296-303
Authors: Meghali Goswami and Christopher S. Hourigan

Genetic and Epigenetic Drug Targets in Myelodysplastic Syndromes

Journal: Current Pharmaceutical Design
Volume: 23,Issue: 1
Page: 135-169
Authors: Karmen Stankov, Suncica Stankov and Jasmina Katanic

Implications of Somatic Mutations in the AML1/RUNX1 Gene in Myelodysplastic Syndrome (MDS): Future Molecular Therapeutic Directions for MDS

Journal: Current Cancer Drug Targets
Volume: 6,Issue: 6
Page: 553-563
Authors: Hironori Harada, Yuka Harada and Akiro Kimura

Monoclonal Antibodies for the Treatment of Acute Myeloid Leukemia

Journal: Current Pharmaceutical Biotechnology
Volume: 7,Issue: 5
Page: 343-369
Authors: Syed A. Abutalib and Martin S. Tallman

Arsenic Trioxide in Hematological Malignancies: The New Discovery of an Ancient Drug

Journal: Current Pharmaceutical Biotechnology
Volume: 7,Issue: 6
Page: 397-405
Authors: A. Bonati, V. Rizzoli and P. Lunghi

Synergistic Cytotoxic Activity of Recombinant TRAIL Plus the Non-Genotoxic Activator of the p53 Pathway Nutlin-3 in Acute Myeloid Leukemia Cells

Journal: Current Drug Metabolism
Volume: 8,Issue: 4
Page: 395-403
Authors: Paola Secchiero, Carlotta Zerbinati, Maria Grazia di Iasio, Elisabetta Melloni, Mario Tiribelli, Vittorio Grill and Giorgio Zauli

Strategies for Biology- and Molecular-Based Treatment of Myelodysplastic Syndromes

Journal: Current Drug Targets
Volume: 6,Issue: 6
Page: 713-725
Authors: E. H. Lindberg

Flt3 Receptor Tyrosine Kinase as a Drug Target in Leukemia

Journal: Current Pharmaceutical Design
Volume: 10,Issue: 16
Page: 1867-1883
Authors: Dirk Schmidt-Arras, Joachim Schwable, Frank- D. Bohmer and Hubert Serve

Single Autosomal Trisomy in Acute Myeloid Leukemia and Myelodysplastic Syndrome

Journal: Current Genomics
Volume: 1,Issue: 2
Page: 153-173
Authors: S. K. Ma and T. S.K. Wan

Membrane Tyrosine Kinase Receptors are an Important Target for the Therapy of Acute Myeloid Leukemia

Journal: Current Cancer Therapy Reviews
Volume: 4,Issue: 1
Page: 31-49
Authors: Ugo Testa

Deregulation of the Mitochondrial Apoptotic Machinery and Development of Molecular Targeted Drugs in Acute Myeloid Leukemia

Journal: Current Cancer Drug Targets
Volume: 8,Issue: 3
Page: 207-222
Authors: G. Del Poeta, A. Bruno, M. I. Del Principe, A. Venditti, L. Maurillo, F. Buccisano, R. Stasi, B. Neri, F. Luciano, A. Siniscalchi, P. de Fabritiis and S. Amadori

Small Molecules ATP-Competitive Inhibitors of FLT3: A Chemical Overview

Journal: Current Medicinal Chemistry
Volume: 15,Issue: 29
Page: 3113-3132
Authors: S. Schenone, C. Brullo and M. Botta

Antitumor Properties and Modulation of Antioxidant Enzymes Activity by Aloe vera Leaf Active Principles Isolated via Supercritical Carbon Dioxide Extraction

Journal: Current Medicinal Chemistry
Volume: 17,Issue: 2
Page: 129-138
Authors: H. A. El-Shemy, M. A.M. Aboul-Soud, A. A. Nassr-Allah, K. M. Aboul-Enein, A. Kabash and A. Yagi

The Crosstalk Between the Matrix Metalloprotease System and the Chemokine Network in Acute Myeloid Leukemia

Journal: Current Medicinal Chemistry
Volume: 17,Issue: 36
Page: 4448-4461
Authors: K. J. Hatfield, H. Reikvam and O. Bruserud

Novel and Emerging Drugs for Acute Myeloid Leukemia: Pharmacology and Therapeutic Activity

Journal: Current Medicinal Chemistry
Volume: 18,Issue: 5
Page: 638-666
Authors: T. Robak, A. Szmigielska-Kaplon, A. Pluta, O. Grzybowska-Izydorczyk, A. Wolska, M. Czemerska and A Wierzbowska

The Hsp32 Inhibitors SMA-ZnPP and PEG-ZnPP Exert Major Growth-Inhibitory Effects on CD34+/CD38+ and CD34+/CD38- AML Progenitor Cells

Journal: Current Cancer Drug Targets
Volume: 12,Issue: 1
Page: 51-63
Authors: H. Herrmann, M. Kneidinger, S. Cerny-Reiterer, T. Rulicke, M. Willmann, K. V. Gleixner, K. Blatt, G. Hormann, B. Peter, P. Samorapoompichit, W. Pickl, G. Y. Bharate, M. Mayerhofer, W. R. Sperr, H. Maeda and P. Valent

Targeting Ion Channels in Leukemias: A New Challenge for Treatment

Journal: Current Medicinal Chemistry
Volume: 19,Issue: 5
Page: 683-696
Authors: A. Arcangeli, S. Pillozzi and A. Becchetti

Acute Myeloid Leukemia in the Elderly: Current Therapeutic Results and Perspectives for Clinical Research

Journal: Reviews on Recent Clinical Trials
Volume: 2,Issue: 1
Page: 33-41
Authors: Felicetto Ferrara and Antonio Pinto

Novel Purine Nucleoside Analogues for Hematological Malignancies

Journal: Recent Patents on Anti-Cancer Drug Discovery
Volume: 3,Issue: 2
Page: 123-136
Authors: Anna Korycka, Ewa Lech-Maranda and Tadeusz Robak


The Role of FLT3 Kinase as an AML Therapy Target

Journal: Current Pharmaceutical Design
Volume: 18,Issue: 19
Page: 2758-2765
Authors: Michal Beffinger and Anna Skwarska

State of the Art of the Therapeutic Perspective of Sorafenib Against Hematological Malignancies

Journal: Current Medicinal Chemistry
Volume: 19,Issue: 28
Page: 4875-4884
Authors: G. Zauli, R. Voltan, V. Tisato and P. Secchiero

Mechanistic Insights into the Antileukemic Activity of Hyperforin

Journal: Current Cancer Drug Targets
Volume: 13,Issue: 1
Page: 1-10
Authors: C. Billard, F. Merhi and B. Bauvois

Targeted Anti-leukemic Therapy as Disease-stabilizing Treatment for Acute Myeloid Leukemia Relapse after Allogeneic Stem Cell Transplantation: Will it be Possible to Combine these Strategies with Retransplantation or Donor Lymphocyte Infusions?

Journal: Current Cancer Drug Targets
Volume: 13,Issue: 1
Page: 30-47
Authors: Hakon Reikvam, Astrid Olsnes Kittang, Guro Melve, Knut Anders Mosevoll, Pal Tore Bentsen, Elisabeth Ersvaer, Bjorn Tore Gjertsen and Oystein Bruserud

The Therapeutical Potential of a Novel Pterocarpanquinone LQB-118 to Target Inhibitor of Apoptosis Proteins in Acute Myeloid Leukemia Cells

Journal: Anti-Cancer Agents in Medicinal Chemistry
Volume: 13,Issue: 2
Page: 341-351
Authors: Flaviana R. de Souza Reis, Fernanda C. Casal de Faria, Carolina P. Castro, Paloma S. de Souza, Flavia da Cunha Vasconcelos, Reinaldo D. Bello, Alcides J. da Silva, Paulo R.R. Costa and Raquel C. Maia

Triazene Compounds in the Treatment of Acute Myeloid Leukemia: A Short Review and a Case Report

Journal: Current Medicinal Chemistry
Volume: 20,Issue: 19
Page: 2389-2401
Authors: L. Bonmassar, F. Marchesi, E. Pascale, O. Franzese, G.P. Margison, A. Bianchi, S. D’Atri, S. Bernardini, D. Lattuada, E. Bonmassar and A. Aquino

Optimizing Outcomes Following Allogeneic Hematopoietic Progenitor Cell Transplantation in AML: The Role of Hypomethylating Agents

Journal: Current Cancer Drug Targets
Volume: 13,Issue: 6
Page: 661-669
Authors: Massimo Martino, Roberta Fedele, Tiziana Moscato and Francesca Ronco

How Recent Advances in High-risk Myelodysplastic Syndrome Physiopathology May Impact Future Treatments

Journal: Current Pharmaceutical Design
Volume: 19,Issue: 30
Page: 5362-5373
Authors: Thomas Cluzeau, Guillaume Robert, Arnaud Jacquel and Patrick Auberger

Fractal Analysis of the Bone Marrow in Myelodysplastic Syndromes

Journal: Current Bioinformatics
Volume: 9,Issue: 4
Page: 408-413
Authors: Giorgio Bianciardi and Pietro Luzi

Strategic Role of Nuclear Inositide Signalling in Myelodysplastic Syndromes Therapy

Journal: Mini-Reviews in Medicinal Chemistry
Volume: 14,Issue: 11
Page: 873-883
Authors: Lucia Manzoli, Sara Mongiorgi, Cristina Clissa, Carlo Finelli, Anna Maria Billi, Alessandro Poli, Marilisa Quaranta, Lucio Cocco and Matilde Y. Follo

The Nuclear Orphan Receptor NR4A1 and NR4A3 as Tumor Suppressors in Hematologic Neoplasms

Journal: Current Drug Targets
Volume: 16,Issue: 1
Page: 38-46
Authors: Kerstin Wenzl, Katharina Troppan, Peter Neumeister and Alexander J.A. Deutsch

Xenograft models of primary acute myeloid leukemia for the development of imaging strategies and evaluation of novel targeted therapies.

Journal: Current Pharmaceutical Biotechnology
Volume: 17,Issue: 1
Page: 42-51
Authors: Pascal Gelebart, Mihaela Popa and Emmet McCormack

New Developments of Differentiation Therapy of Acute Myeloid Leukemia

Journal: Current Pharmacogenomics and Personalized Medicine
Volume: 14,Issue: 2
Page: 86-105
Authors: Germana Castelli, Elvira Pelosi and Ugo Testa

Membrane Tyrosine Kinase Receptors Kit and FLT3 are an Important Targets for the Therapy of Acute Myeloid Leukemia

Journal: Current Cancer Therapy Reviews
Volume: 9,Issue: 3
Page: 181-219
Authors: Ugo Testa

Results 1 - 70 of 70