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ACETYLCHOLINE
Results 1 - 413 of 413
Development of Mediator-Free Acetylcholine Biosensor Based on Acetylcholine Oxidase Immobilized Micro-Chips

Journal: Current Proteomics
Volume: 9,Issue: 4
Page: 272-279
Authors: Mohammed Muzibur Rahman

In Silico Analysis of Binding Interaction of Mamba Toxins with M4 and M2 Muscarinic Acetylcholine Receptors for Therapeutic Use in Alzheimer’s Disease

Journal: CNS & Neurological Disorders - Drug Targets
Volume: 14,Issue: 8
Page: 1031-1040
Authors: Maleeha Waqar, Mohammad Amjad Kamal and Sidra Batool

Binding Mode of α-Conotoxins to an Acetylcholine Binding Protein Determined by Saturation Transfer Difference NMR

Journal: Protein & Peptide Letters
Volume: 15,Issue: 9
Page: 910-914
Authors: Jan-Christoph Westermann, Richard J. Clark and David J. Craik

A Hydrazide Linker Strategy for Heterobivalent Compounds as Ortho- and Allosteric Ligands of Acetylcholine-Binding Proteins

Journal: Current Topics in Medicinal Chemistry
Volume: 11,Issue: 22
Page: 2731-2748
Authors: Paul W. Elsinghorst, Wolfgang Hartig, Daniela Gundisch, Klaus Mohr, Christian Trankle and Michael Gutschow

Molecular and Physicochemical Aspects of Local Anesthetics Acting on Nicotinic Acetylcholine Receptor-containing Membranes

Journal: Mini-Reviews in Medicinal Chemistry
Volume: 2,Issue: 4
Page: 385-410
Authors: Hugo R. Arias and Michael P. Blanton

Role of the α7 Nicotinic Acetylcholine Receptor and RIC-3 in the Cholinergic Anti-inflammatory Pathway

Journal: Central Nervous System Agents in Medicinal Chemistry
Volume: 17,Issue: 2
Page: 90-99
Authors: Treinin Millet, Papke L. Roger, Nizri Eran, Ben-David Yael, Mizrachi Tehila and Brenner Talma*

Synthesis of Poison-Frog Alkaloids and Their Pharmacological Effects at Neuronal Nicotinic Acetylcholine Receptors

Journal: Current Chemical Biology
Volume: 1,Issue: 1
Page: 97-114
Authors: Naoki Toyooka, Hiroshi Tsuneki, Soushi Kobayashi, Zhou Dejun, Masashi Kawasaki, Ikuko Kimura, Toshiyasu Sasaoka and Hideo Nemoto

On the Physiological Relevance of Muscarinic Acetylcholine Receptors in Alzheimers Disease

Journal: Current Medicinal Chemistry
Volume: 12,Issue: 24
Page: 2915-2921
Authors: H. J. Koch, S. Haas and T. Jurgens

Nicotinic Acetylcholine Receptors and Imaging

Journal: Current Pharmaceutical Design
Volume: 6,Issue: 11
Page: 1143-1157
Authors: Daniela Gundisch

Development of Vesicular Acetylcholine Transporter Ligands: Molecular Probes for Alzheimers Disease

Journal: Current Bioactive Compounds
Volume: 6,Issue: 3
Page: 129-155
Authors: Nicolas Giboureau, Kylee M. Aumann, Corinne Beinat and Michael Kassiou

Nicotinic Acetylcholine Receptors as Drug Targets

Journal: Current Drug Target -CNS & Neurological Disorders
Volume: 3,Issue: 2
Page: 123-130
Authors: R. C. Hogg and D. Bertrand

Inhibition of p53 Mutant Peptide Aggregation In Vitro by Cationic Osmolyte Acetylcholine Chloride

Journal: Protein & Peptide Letters
Volume: 24,Issue: 4
Page: 353-357
Authors: Zhaolin Chen and Mathumai Kanapathipillai

The Design, Synthesis and Screening of a Muscarinic Acetylcholine Receptor Targeted Compound Library

Journal: Combinatorial Chemistry & High Throughput Screening
Volume: 8,Issue: 7
Page: 649-653
Authors: Jurgen Benting, Merisa Leonhardt, Stephen D. Lindell and Jorg Tiebes

Muscarinic Acetylcholine Receptors

Journal: Current Pharmaceutical Design
Volume: 12,Issue: 28
Page: 3573-3581
Authors: Masaru Ishii and Yoshihisa Kurachi

Agonists at the a4b2 Nicotinic Acetylcholine Receptors Relationships and Molecular Modelling

Journal: Current Medicinal Chemistry
Volume: 8,Issue: 6
Page: 651-674
Authors: J. E. Tonder and P. H. Olesen

Muscarinic Acetylcholine Receptor-Interacting Proteins (mAChRIPs): Targeting the Receptorsome

Journal: Current Drug Targets
Volume: 13,Issue: 1
Page: 53-71
Authors: D. O. Borroto-Escuela, Luigi F. Agnati, Kjell Fuxe and F. Ciruela

PET Radioligands for the Vesicular Acetylcholine Transporter (VAChT)

Journal: Current Topics in Medicinal Chemistry
Volume: 10,Issue: 15
Page: 1569-1583
Authors: Nicolas Giboureau, Ian Mat Som, Aurelie Boucher-Arnold, Denis Guilloteau and Michael Kassiou

Endogenous Acetylcholine Controls the Severity of Polymicrobial Sepsisassociated Inflammatory Response in Mice

Journal: Current Neurovascular Research
Volume: 13,Issue: 1
Page: 4-9
Authors: Flávio Almeida Amaral, Caio Tavares Fagundes, Aline Silva Miranda, Vivian Vasconceios Costa, Livia Resende, Danielle da Gloria de Souza, Vania Ferreira Prado, Mauro Martins Teixeira, Marco Antonio Maximo Prado and Antonio Lucio Teixeira

Nicotinic Acetylcholine Receptor Interaction with β -Amyloid: Molecular, Cellular, and Physiological Consequences

Journal: Current Alzheimer Research
Volume: 7,Issue: 1
Page: 27-39
Authors: H. R. Parri and K. T. Dineley

α7 Nicotinic Acetylcholine Receptors: A Therapeutic Target in the Structure Era

Journal: Current Drug Targets
Volume: 13,Issue: 5
Page: 695-706
Authors: Antoine Taly and Sebastien Charon

Dynamics of Nicotinic Acetylcholine Receptors and Receptor-Associated Proteins at the Vertebrate Neuromuscular Junction

Journal: Current Alzheimer Research
Volume: 10,Issue: 6
Page: 631-641
Authors: Marcelo Pires-Oliveira, Derek Moen and Mohammed Akaaboune

α7 Nicotinic Acetylcholine Receptors in Alzheimer’s Disease: Neuroprotective, Neurotrophic or Both?

Journal: Current Drug Targets
Volume: 13,Issue: 5
Page: 613-622
Authors: Caterina M. Hernandez and Kelly T. Dineley

alpha Conotoxins Nicotinic Acetylcholine Receptor Antagonists as Pharmacological Tools and Potential Drug Leads

Journal: Current Medicinal Chemistry
Volume: 8,Issue: 4
Page: 327-344
Authors: Julie L. Dutton and David J. Craik

α7 Nicotinic Acetylcholine Receptor as a Potential Therapeutic Target for Schizophrenia

Journal: Current Pharmaceutical Design
Volume: 17,Issue: 2
Page: 121-129
Authors: Masatomo Ishikawa and Kenji Hashimoto

Quantitative Molecular Imaging of Neuronal Nicotinic Acetylcholine Receptors in the Human Brain with A-85380 Radiotracers

Journal: Current Medical Imaging Reviews
Volume: 7,Issue: 2
Page: 107-112
Authors: Shahrdad Lotfipour, Mark Mandelkern and Arthur L. Brody

Design of Ligands for the Nicotinic Acetylcholine Receptors:The Quest for Selectivity

Journal: Current Topics in Medicinal Chemistry
Volume: 4,Issue: 3
Page: 299-334
Authors: W.H. Bunnelle, Manlio M.J. Dart and M.R. Schrimpf

Recent Developments in the Synthesis of Nicotinic Acetylcholine Receptor Ligands

Journal: Current Topics in Medicinal Chemistry
Volume: 4,Issue: 6
Page: 609-629
Authors: Scott R. Breining

Neuronal Nicotinic Acetylcholine Receptors - Targets for the Development of Drugs to Treat Cognitive Impairment Associated with Schizophrenia and Alzheimers Disease

Journal: Current Topics in Medicinal Chemistry
Volume: 10,Issue: 2
Page: 144-152
Authors: Simon N. Haydar and John Dunlop

Nicotinic Acetylcholine Receptors and Epilepsy

Journal: Current Drug Target -CNS & Neurological Disorders
Volume: 1,Issue: 4
Page: 443-448
Authors: Ortrud K. Steinlein

Development of Radioligands for the Imaging of α7 Nicotinic Acetylcholine Receptors with Positron Emission Tomography

Journal: Current Drug Targets
Volume: 13,Issue: 5
Page: 594-601
Authors: Peter Brust, Dan Peters and Winnie Deuther-Conrad

Stress and the α7 Nicotinic Acetylcholine Receptor

Journal: Current Drug Targets
Volume: 13,Issue: 5
Page: 607-612
Authors: Richard G. Hunter

α7 Nicotinic Acetylcholine Receptor Subunit in Angiogenesis and Epithelial to Mesenchymal Transition

Journal: Current Drug Targets
Volume: 13,Issue: 5
Page: 671-679
Authors: Smitha Pillai and Srikumar Chellappan

The Structural Features of α-Conotoxin Specifically Target Different Isoforms of Nicotinic Acetylcholine Receptors

Journal: Current Topics in Medicinal Chemistry
Volume: 16,Issue: 2
Page: 156-169
Authors: Rui-Jie Wu, Lei Wang and Hui Xiang

Allosteric Modulation of Muscarinic Acetylcholine Receptors

Journal: Current Neuropharmacology
Volume: 5,Issue: 3
Page: 157-167
Authors: Karen J. Gregory, Patrick M. Sexton and Arthur Christopoulos

Naturally Occurring and Synthetic Peptides Acting on Nicotinic Acetylcholine Receptors

Journal: Current Pharmaceutical Design
Volume: 15,Issue: 21
Page: 2430-2452
Authors: Igor E. Kasheverov, Yuri N. Utkin and Victor I. Tsetlin

Targeting α7 Nicotinic Acetylcholine Receptors in the Treatment of Schizophrenia

Journal: Current Pharmaceutical Design
Volume: 16,Issue: 5
Page: 538-554
Authors: Mihaly Hajos and Bruce N. Rogers

Advances in the Discovery of Novel Positive Allosteric Modulators of the α7 Nicotinic Acetylcholine Receptor

Journal: Recent Patents on CNS Drug Discovery
Volume: 2,Issue: 2
Page: 99-106
Authors: Ramin Faghih, Gregory A. Gfesser and Murali Gopalakrishnan

Muscarinic Acetylcholine Receptors: New Potential Therapeutic Targets in Antinociception and in Cancer Therapy

Journal: Recent Patents on CNS Drug Discovery
Volume: 3,Issue: 2
Page: 94-103
Authors: Ada Maria Tata

Regulation of Nicotinic Acetylcholine Receptor Numbers and Function by Chronic Nicotine Exposure

Journal: Current Drug Target -CNS & Neurological Disorders
Volume: 1,Issue: 4
Page: 359-385
Authors: C. L. Gentry and R. J. Lukas

Traumatic Brain Injury: Central and Peripheral Role of α7 Nicotinic Acetylcholine Receptors

Journal: Current Drug Targets
Volume: 13,Issue: 5
Page: 631-636
Authors: Matthew L. Kelso and Julie H. Oestreich

Pharmacological Approaches to Targeting Muscarinic Acetylcholine Receptors

Journal: Recent Patents on CNS Drug Discovery
Volume: 9,Issue: 2
Page: 85-100
Authors: Carlo Matera and Ada M. Tata

Nicotinic Acetylcholine Receptors in the Pathophysiology of Al zheimer’s Disease: The Role of Protein-Protein Interactions in Current and Future Treatment

Journal: Current Pharmaceutical Design
Volume: 22,Issue: 14
Page: 2015-2034
Authors: Morten Skøtt Thomsen, Jesper Tobias Andreasen, Maria Arvaniti and Kristi Anne Kohlmeier

Design and Development of Resveratrol NLCs and their Role in Synaptic Transmission of Acetylcholine in C. elegans Model

Journal: Current Drug Therapy
Volume: 12,Issue: 2
Page: 134-148
Authors: Anubhav Anand, Malti Arya, Gyanendra Singh, Gaurav Kaithwas and Shubhini A. Saraf*

Modes of Action, Resistance and Toxicity of Insecticides Targeting Nicotinic Acetylcholine Receptors

Journal: Current Medicinal Chemistry
Volume: 24,Issue: 27
Page: 2925-2934
Authors: Makoto Ihara, Steven D. Buckingham, Kazuhiko Matsuda and David B. Sattelle*

Molecular Dynamics of Nicotinic Acetylcholine Receptor Correlating Biological Functions

Journal: Current Protein & Peptide Science
Volume: 7,Issue: 3
Page: 195-200
Authors: Yechun Xu, Xiaomin Luo, Jianhua Shen, Weiliang Zhu, Kaixian Chen and Hualiang Jiang

Impact of Genetic Variability in Nicotinic Acetylcholine Receptors on Nicotine Addiction and Smoking Cessation Treatment

Journal: Current Medicinal Chemistry
Volume: 18,Issue: 1
Page: 91-112
Authors: P. Russo, A. Cesario, S. Rutella, G. Veronesi, L. Spaggiari, D. Galetta, S. Margaritora, P. Granone and D. S. Greenberg

Anesthetics as Chemical Tools to Study the Structure and Function of Nicotinic Acetylcholine Receptors

Journal: Current Protein & Peptide Science
Volume: 6,Issue: 5
Page: 451-472
Authors: Hugo R. Arias and Pankaj Bhumireddy

Possible Drug Candidates for Alzheimers Disease Deduced from Studying their Binding Interactions with α7 Nicotinic Acetylcholine Receptor

Journal: Medicinal Chemistry
Volume: 5,Issue: 3
Page: 250-262
Authors: Ruo-Xu Gu, Hui Gu, Zhi-Yuan Xie, Jing-Fang Wang, Hugo R. Arias, Dong-Qing Wei and Kuo-Chen Chou

Discovery and Development of a Potent and Highly Selective Small Molecule Muscarinic Acetylcholine Receptor Subtype I (mAChR 1 or M1) Antagonist In Vitro and In Vivo Probe

Journal: Current Topics in Medicinal Chemistry
Volume: 9,Issue: 13
Page: 1217-1226
Authors: C. David Weaver, Douglas J. Sheffler, L. Michelle Lewis, Thomas M. Bridges, Richard Williams, Natalia T. Nalywajko, J. Phillip Kennedy, Matthew M. Mulder, Satyawan Jadhav, Leslie A. Aldrich, Carrie K. Jones, Joy Marlo, Colleen M. Niswender, Matthew M. Mock, Fang Zheng, P. Jeffrey Conn and Craig W. Lindsley

Recent Development of Radioligands for Imaging α7 Nicotinic Acetylcholine Receptors in the Brain

Journal: Current Topics in Medicinal Chemistry
Volume: 10,Issue: 15
Page: 1544-1557
Authors: Jun Toyohara, Jin Wu and Kenji Hashimoto

Neuronal Nicotinic Acetylcholine Receptors as Pharmacotherapeutic Targets for the Treatment of Alcohol Use Disorders

Journal: CNS & Neurological Disorders - Drug Targets
Volume: 9,Issue: 1
Page: 60-76
Authors: S. Chatterjee and S. E. Bartlett

α7 Nicotinic Acetylcholine Receptor Mediated Neuroprotection in Parkinson’s Disease

Journal: Current Drug Targets
Volume: 13,Issue: 5
Page: 623-630
Authors: Jun Kawamata, Syuuichirou Suzuki and Shun Shimohama

Role of α7-Nicotinic Acetylcholine Receptor in Normal and Cancer Stem Cells

Journal: Current Drug Targets
Volume: 13,Issue: 5
Page: 656-665
Authors: Waka Lin, Naoya Hirata and Yuko Sekino and Yasunari Kanda

2D-QSAR Studies of Tacrine Analogues for Acetylcholine Esterase (AChE) Inhibition using Multiple Linear Regression Analysis

Journal: Letters in Drug Design & Discovery
Volume: 9,Issue: 9
Page: 858-866
Authors: Prabhakar S. Achanta, Rajasekhar Reddy Alavala, Umasankar Kulandaivelu, Shireesha Boyapati and Kundan Ingale

Roles of Nicotinic Acetylcholine Receptors in Stem Cell Survival/Apoptosis, Proliferation and Differentiation

Journal: Current Molecular Medicine
Volume: 13,Issue: 9
Page: 1455-1464
Authors: J. -X. Shen, D. Qin, H. Wang, C. Wu, F. -D. Shi and J. Wu

Alpha9Alpha10 Nicotinic Acetylcholine Receptors as Target for the Treatment of Chronic Pain

Journal: Current Pharmaceutical Design
Volume: 20,Issue: 38
Page: 6042-6047
Authors: Alessandra Del Bufalo, Alfredo Cesario, Gianluca Salinaro, Massimo Fini and Patrizia Russo

Structural Analysis of Muscarinic Acetylcholine Receptor Type 1 Intracellular Loop 3 by Hydrogen/Deuterium Exchange Mass Spectrometry

Journal: Protein & Peptide Letters
Volume: 22,Issue: 1
Page: 94-100
Authors: In Y. Ko, Dong K. Kim and Ka Y. Chung

Targeting Brain Nicotinic Acetylcholine Receptors to Treat Major Depression and Co-Morbid Alcohol or Nicotine Addiction

Journal: CNS & Neurological Disorders - Drug Targets
Volume: 14,Issue: 5
Page: 647-653
Authors: Shafiqur Rahman

Allosteric Modulation of Nicotinic Acetylcholine Receptors: The Concept and Therapeutic Trends

Journal: Current Pharmaceutical Design
Volume: 22,Issue: 14
Page: 1986-1997
Authors: Victor V. Uteshev

Targeting the Nicotinic Acetylcholine Receptors (nAChRs) in Astrocytes as a Potential Therapeutic Target in Parkinson’s Disease

Journal: Current Pharmaceutical Design
Volume: 22,Issue: 10
Page: 1305-1311
Authors: Juan Camilo Jurado-Coronel, Marco Avila-Rodriguez, Francisco Capani, Janneth Gonzalez, Valentina Echeverria Moran and George E. Barreto

The Recent Development of α7 Nicotinic Acetylcholine Receptor (nAChR) Ligands as Therapeutic Candidates for the Treatment of Central Nervous System (CNS) Diseases

Journal: Current Pharmaceutical Design
Volume: 22,Issue: 14
Page: 2134-2151
Authors: Corinne Beinat, Samuel D. Banister, Marco Herrera and Michael Kassiou

Levamisole: A Positive Allosteric Modulator for the α3β4 Nicotinic Acetylcholine Receptors Prevents Weight Gain in the CD-1 Mice on a High Fat Diet

Journal: Current Pharmaceutical Design
Volume: 23,Issue: 12
Page: 1869-1872
Authors: Jeanne A. Lewis, Jerrel L. Yakel and Anshul A. Pandya*

Neuroprotective and Neurotoxic Implications of α7 Nicotinic Acetylcholine Receptor and Aβ Interaction: Therapeutic Options in Alzheimer's Disease

Journal: Current Drug Targets
Volume: 18,Issue: 13
Page: 1537-1544
Authors: Syeda Mehpara Farhat and Touqeer Ahmed*

Targeting α7 Nicotinic Acetylcholine Receptor to Combat Inflammation in Cardio-Cerebral-Vascular Diseases

Journal: Current Drug Targets
Volume: 18,Issue: 15
Page: 1779-1784
Authors: Hui Fu, Min Ni, Ji-Kuai Chen, Ting Zhao, Ya-Ping Deng, Dong-Jie Li, Guo-Jun Jiang* and Fu-Ming Shen*

Targeting the Alpha 7 Nicotinic Acetylcholine Receptor to Reduce Amyloid Accumulation in Alzheimers Disease Pyramidal Neurons

Journal: Current Pharmaceutical Design
Volume: 12,Issue: 6
Page: 677-684
Authors: Michael R. D`Andrea and Robert G. Nagele

Selective α7 Nicotinic Acetylcholine Receptor Ligands

Journal: Current Medicinal Chemistry
Volume: 13,Issue: 13
Page: 1567-1584
Authors: Anatoly Mazurov, Terry Hauser and Craig H. Miller

The Quest for Eldorado: Development of Radioligands for In Vivo Imaging of Nicotinic Acetylcholine Receptors in Human Brain

Journal: Current Pharmaceutical Design
Volume: 12,Issue: 30
Page: 3877-3900
Authors: Andrew G. Horti and Victor L. Villemagne

Ligands of Neuronal Nicotinic Acetylcholine Receptor (nAChR): Inferences from the Hansch and 3-D Quantitative Structure-Activity Relationship (QSAR) Models

Journal: Current Medicinal Chemistry
Volume: 9,Issue: 1
Page: 1-29
Authors: O. Nicolotti, M. Pellegrini-Calace, C. Altomare, A. Carotti, A. Carrieri and F. Sanz

Pathways of Acetylcholine Synthesis, Transport and Release as Targets for Treatment of Adult-Onset Cognitive Dysfunction

Journal: Current Medicinal Chemistry
Volume: 15,Issue: 5
Page: 488-498
Authors: F. Amenta and S. K. Tayebati

Cognitive Improvement by Activation of α7 Nicotinic Acetylcholine Receptors: From Animal Models to Human Pathophysiology

Journal: Current Pharmaceutical Design
Volume: 16,Issue: 3
Page: 323-343
Authors: Morten S. Thomsen, Henrik H. Hansen, Mikkelsen B. Timmerman and Jens D. Mikkelsen

Functional Central Nicotinic Acetylcholine Receptor Antagonism by Systemic Administration of Tinuvin 770 (BTMPS)

Journal: Current Alzheimer Research
Volume: 2,Issue: 2
Page: 141-147
Authors: John H. Graham, Roger L. Papke and Jerry J. Buccafusco

Nicotinic Acetylcholine Receptor Agonists: A Potential New Class of Analgesics

Journal: Current Topics in Medicinal Chemistry
Volume: 4,Issue: 3
Page: 369-384
Authors: M.W. Decker, L.E. Rueter and R.S. Bitner

Nicotinic Receptors and the Treatment of Attentional and Cognitive Deficits in Neuropsychiatric Disorders: Focus on the α7 Nicotinic Acetylcholine Receptor as a Promising Drug Target for Schizophrenia

Journal: Central Nervous System Agents in Medicinal Chemistry
Volume: 7,Issue: 4
Page: 269-288
Authors: Christian Chiamulera and Guido Fumagalli

Muscarinic Acetylcholine Receptors: Relevance to Infertility and Male Contraception

Journal: Immunology‚ Endocrine & Metabolic Agents in Medicinal Chemistry
Volume: 8,Issue: 1
Page: 42-50
Authors: C. S. Porto, T. F.G. Lucas, E. R. Siu, C. Royer, E. S. Trindade, H. B. Nader and M. F.M. Lazari

Recent Progress in the Development of Subtype Selective Nicotinic Acetylcholine Receptor Ligands

Journal: Current Drug Target -CNS & Neurological Disorders
Volume: 1,Issue: 4
Page: 337-348
Authors: P. C. Astles, S. R. Baker, J. R. Boot, L. M. Broad, C. P. Dell and M. Keenan

The Role of Neuronal Nicotinic Acetylcholine Receptors in Acute and Chronic Neurodegeneration

Journal: Current Drug Target -CNS & Neurological Disorders
Volume: 1,Issue: 4
Page: 399-411
Authors: M. J. O'Neill, T. K. Murray, V. Lakics, N. P. Visanji and S. Duty

Multiple Species Metabolism of PHA-568487, A Selective α7 Nicotinic Acetylcholine Receptor Agonist

Journal: Drug Metabolism Letters
Volume: 4,Issue: 3
Page: 163-172
Authors: F. Barclay Shilliday, Daniel P. Walker, Chungang Gu, Xiaojun Fang, Bruce Thornburgh, Gwendolyn D. Fate and J. Scott Daniels

Functional Crosstalk Between β2-adrenoreceptor and Muscarinic Acetylcholine Receptor: Implications for Gene-Gene Interactions and Bronchodilatory Responses in Patients with Asthma and COPD

Journal: Current Pharmacogenomics and Personalized Medicine
Volume: 6,Issue: 4
Page: 302-319
Authors: Takahiro Yoshikawa and Hiroshi Kanazawa

α7-Nicotinic Acetylcholine Receptors: An Old Actor for New Different Roles

Journal: Current Drug Targets
Volume: 13,Issue: 5
Page: 574-578
Authors: Patrizia Russo and Antoine Taly

The α7 Nicotinic Acetylcholine Receptor Complex: One, Two or Multiple Drug Targets?

Journal: Current Drug Targets
Volume: 13,Issue: 5
Page: 707-720
Authors: Morten S. Thomsen and Jens D. Mikkelsen

Methylene Blue Inhibits the Function of α7-Nicotinic Acetylcholine Receptors

Journal: CNS & Neurological Disorders - Drug Targets
Volume: 11,Issue: 6
Page: 791-800
Authors: Abdulla S. Al Mansouri, Dietrich E. Lorke, Syed M. Nurulain, Abrar Ashoor, Susan Yang Keun-Hang, Georg Petroianu, Dmytro Isaev and Murat Oz

Inhaled Muscarinic Acetylcholine Receptor Antagonists for Treatment of COPD

Journal: Current Medicinal Chemistry
Volume: 20,Issue: 12
Page: 1464-1476
Authors: P. Montuschi, F. Macagno, S. Valente and L. Fuso

On the Interaction of β-Amyloid Peptides and α7-Nicotinic Acetylcholine Receptors in Alzheimer’s Disease

Journal: Current Alzheimer Research
Volume: 10,Issue: 6
Page: 618-630
Authors: Murat Oz, Dietrich E. Lorke, Keun-Hang S. Yang and Georg Petroianu


The Role of α7 Nicotinic Acetylcholine Receptors and α7-Specific Antibodies in Neuroinflammation Related to Alzheimer Disease

Journal: Current Pharmaceutical Design
Volume: 22,Issue: 14
Page: 2035-2049
Authors: Maryna Skok and Olena Lykhmus

Neuronal Acetylcholine Nicotinic Receptors as New Targets for Lung Cancer Treatment

Journal: Current Pharmaceutical Design
Volume: 22,Issue: 14
Page: 2160-2169
Authors: Vanessa Mucchietto, Arianna Crespi, Francesca Fasoli, Francesco Clementi and Cecilia Gotti

Elevations in the Levels of NF-κB and Inflammatory Chemotactic Factors in the Brains with Alzheimer’s Disease - One Mechanism May Involve α3 Nicotinic Acetylcholine Receptor

Journal: Current Alzheimer Research
Volume: 13,Issue: 11
Page: 1290-1301
Authors: Yuan Liao, Xiao-Lan Qi, Ying Cao, Wen-Feng Yu, Rivka Ravid, Bengt Winblad, Jin-Jing Pei and Zhi-Zhong Guan

Synthesis of Mannich Bases by Two Different Methods and Evaluation of their Acetylcholine Esterase and Carbonic Anhydrase Inhibitory Activities

Journal: Letters in Drug Design & Discovery
Volume: 14,Issue: 5
Page: 573-580
Authors: Halise I. Gul*, Alkan Demirtas, Gokbay Ucar, Parham Taslimi and İlhami Gulcin

Neuronal Nicotinic Acetylcholine Receptor Agonists: Pharmacophores, Evolutionary QSAR and 3D-QSAR models

Journal: Current Topics in Medicinal Chemistry
Volume: 4,Issue: 3
Page: 335-360
Authors: O. Nicolotti, C. Altomare, M. Pellegrini-Calace and A. Carotti

Commentary: Research Highlights (Neuronal Nicotinic Acetylcholine Receptors: Emerging Therapeutic Targets for Alcoholism)

Journal: CNS & Neurological Disorders - Drug Targets
Volume: 10,Issue: 5
Page: 526-526
Authors: Shafiqur Rahman

Acetylcholine Receptors and Tau Phosphorylation

Journal: Current Molecular Medicine
Volume: 6,Issue: 4
Page: 423-428
Authors: A. Rubio, M. Pérez and Jesus Ávila

Molecular Modelling and QSAR of Reversible Acetylcholines-terase Inhibitors

Journal: Current Medicinal Chemistry
Volume: 7,Issue: 3
Page: 273-294
Authors: J. Kaur and M. -Q. Zhang


Preface [Hot topic: Nicotinic Acetylcholine Receptors: Ligand Design Issues (Guest Editor: Jeffrey D. Schmitt)]

Journal: Current Topics in Medicinal Chemistry
Volume: 4,Issue: 6
Page: ii-ii
Authors: Jeffrey D. Schmitt

Musings on α4β2 Nicotinic Acetylcholine (nACh) Receptor Pharmacophore Models

Journal: Current Topics in Medicinal Chemistry
Volume: 4,Issue: 6
Page: 631-644
Authors: Richard A. Glennon, Malgorzata Dukat and Liang Liao

The Importance of Nicotinic Acetylcholine Receptors in Schizophrenia, Bipolar Disorder and Tourettes Syndrome

Journal: Current Drug Target -CNS & Neurological Disorders
Volume: 1,Issue: 4
Page: 433-442
Authors: Joseph P. McEvoy and Trina B. Allen

Selective Activation of Muscarinic Acetylcholine Receptors for the Treatment of Schizophrenia

Journal: Current Pharmaceutical Biotechnology
Volume: 13,Issue: 8
Page: 1563-1571
Authors: B. Dean

Bioisosteric Replacement and Related Analogs in the Design, Synthesis and Evaluation of Ligands for Muscarinic Acetylcholine Receptors

Journal: Medicinal Chemistry
Volume: 10,Issue: 4
Page: 361-375
Authors: Richie R. Bhandare and Daniel J. Canney

Desformylflustrabromine: A Novel Positive Allosteric Modulator for beta2 Subunit Containing Nicotinic Receptor Sub-Types

Journal: Current Pharmaceutical Design
Volume: 22,Issue: 14
Page: 2057-2063
Authors: Anshul A. Pandya

[General Articles] Muscarinic and Nicotinic Cholinergic Agonists: Structural Analogies and Discrepancies

Journal: Current Medicinal Chemistry
Volume: 10,Issue: 23
Page: 2611-2620
Authors: Zsolt Bikadi and Miklos Simonyi

Rational Understanding of Nicotinic Receptors Drug Binding

Journal: Current Topics in Medicinal Chemistry
Volume: 4,Issue: 6
Page: 645-651
Authors: Thomas Grutter, Nicolas Le Novere and Jean-Pierre Changeux

Enhanced Butyrylcholinesterase Activity may be the Common Link in Triggering Low-Grade Systemic Inflammation and Decrease in Cognitive Function in Diabetes Mellitus and Alzheimers disease

Journal: Current Nutrition & Food Science
Volume: 4,Issue: 3
Page: 213-216
Authors: Allam A. Rao, C. Siva Reddy, G. R. Sridhar, A. Annapurna, T. Hanuman, M. Prameela, K. Suresh, S. Prasannalaxmi and Undurti N. Das

Molecular Interaction of Acetylcholinesterase with Carnosic Acid Derivatives: A Neuroinformatics Study

Journal: CNS & Neurological Disorders - Drug Targets
Volume: 13,Issue: 3
Page: 440-446
Authors: M. Merad, W. Soufi, S. Ghalem, F. Boukli, M.H. Baig, K. Ahmad and Mohammad A. Kamal

Nicotinic and Glycinergic Medications for Disorders of Hedonic Regulation

Journal: Letters in Drug Design & Discovery
Volume: 4,Issue: 5
Page: 373-381
Authors: M.A. Dyer, R.S. Barr and A.E. Evins

Cholinergic Targets in Lung Cancer

Journal: Current Pharmaceutical Design
Volume: 22,Issue: 14
Page: 2152-2159
Authors: Eliot R. Spindel

Ligand-Gated Pentameric ion Channels, from Binding to Gating

Journal: Current Molecular Pharmacology
Volume: 2,Issue: 3
Page: 253-262
Authors: Gabor Maksay

Trisubstituted Phenolic Compounds as Inhibitors of Acetylcholinesterase and Amyloid Beta Aggregate Formation

Journal: Current Enzyme Inhibition
Volume: 9,Issue: 1
Page: 67-74
Authors: Caroline M. Peckels, Nathan S. Alexander, Gina N. Wilson, Joel M. Karty and Kathryn M. Matera

Cholinergic System Dysfunction and Neurodegenerative Diseases: Cause or Effect?

Journal: CNS & Neurological Disorders - Drug Targets
Volume: 13,Issue: 7
Page: 1294-1303
Authors: Ada M. Tata, Lucia Velluto, Chiara D';Angelo and Marcella Reale

Role of Nicotinic and Muscarinic Receptors on Synaptic Plasticity and Neurological Diseases

Journal: Current Pharmaceutical Design
Volume: 22,Issue: 14
Page: 2004-2014
Authors: Marco Fuenzalida, Miguel Ángel Pérez and Hugo R. Arias

Muscarinic Receptor Agonists and Antagonists in the Treatment of Alzheimers Disease

Journal: Current Pharmaceutical Design
Volume: 11,Issue: 26
Page: 3353-3361
Authors: J. W. Clader and Y. Wang

Effect of a M1 Allosteric Modulator on Scopolamine-Induced Amnesia

Journal: Medicinal Chemistry
Volume: 3,Issue: 1
Page: 7-11
Authors: J. Espinosa-Raya, M. Espinoza-Fonseca, O. Picazo and J. Trujillo-Ferrara

M1 Agonists as a Potential Disease-Modifying Therapy for Alzheimers Disease

Journal: Current Alzheimer Research
Volume: 6,Issue: 2
Page: 112-117
Authors: Antonella Caccamo, Abraham Fisher and Frank M. LaFerla

Endothelial Dysfunction and Coronary Artery Spasm

Journal: Current Drug Target -Cardiovascular & Hematological Disorders
Volume: 4,Issue: 1
Page: 23-33
Authors: Hiroaki Kawano and Hisao Ogawa

Natural Product Inhibitors of Acetylcholinesterase

Journal: Current Organic Chemistry
Volume: 10,Issue: 8
Page: 825-847
Authors: K. Hostettmann, A. Borloz, A. Urbain and A. Marston

Pharmacological Manipulation of the Vasoconstrictive Effects of Amyloid- β Peptides by Donepezil and Rivastigmine

Journal: Current Alzheimer Research
Volume: 3,Issue: 2
Page: 137-145
Authors: Goksel Doganay, Bereha Khodr, George Georgiou and Zeinab Khalil

Functional Neurochemistry of Alzheimers Disease

Journal: Current Pharmaceutical Design
Volume: 10,Issue: 3
Page: 265-293
Authors: Wieland Gsell, Gerd Jungkunz and Peter Riederer

Endomorphins Restored the Endothelium-Dependent Relaxation of the Rabbit Aorta Rings Exposed to High D-Glucose Condition Via NO-cGMP Pathway

Journal: Protein & Peptide Letters
Volume: 13,Issue: 10
Page: 1037-1044
Authors: Jing Liu, Wei-Min Wu, Juan-Juan Che, Jun Zhang and Rui Wang

Nerve Membrane Ion Channels as the Target Site of Insecticides

Journal: Mini-Reviews in Medicinal Chemistry
Volume: 2,Issue: 4
Page: 419-432
Authors: Toshio Narahashi

Recent Advances in the Medicinal Chemistry of Polyamine Toxins

Journal: Mini-Reviews in Medicinal Chemistry
Volume: 1,Issue: 4
Page: 317-338
Authors: Kristian Stromgaard, Kim Andersen, Povl Krogsgaard-Larsen and Jerzy W. Jaroszewski

Neuro-Transmitters in the Central Nervous System & their Implication in Learning and Memory Processes

Journal: Current Medicinal Chemistry
Volume: 16,Issue: 7
Page: 796-840
Authors: Helton J. Reis, Cristina Guatimosim, Maryse Paquet, Magda Santos, Fabiola M. Ribeiro, Arthur Kummer, Grace Schenatto, Joao V. Salgado, Luciene B. Vieira, Antonio L. Teixeira and Andras Palotas

Structural Basis of Agonist Selectivity for Different nAChR Subtypes: Insights from Crystal Structures, Mutation Experiments and Molecular Simulations

Journal: Current Pharmaceutical Design
Volume: 17,Issue: 17
Page: 1652-1662
Authors: Ruo-Xu Gu, Yu-Qing Zhong and Dong-Qing Wei

Emerging Pharmacological Properties of Cholinergic Synaptic Transmission: Comparison between Mammalian and Insect Synaptic and Extrasynaptic Nicotinic Receptors

Journal: Current Neuropharmacology
Volume: 9,Issue: 4
Page: 706-714
Authors: Steeve H. Thany and Helene Tricoire-Leignel

Nicotine, Body Weight and Potential Implications in the Treatment of Obesity

Journal: Current Topics in Medicinal Chemistry
Volume: 3,Issue: 8
Page: 899-919
Authors: Ming D. Li, Justin K. Kane and Ozlen Konu

Lobeline Docking on AChBP and Nicotinic Receptors: Discriminating Importance of the Pocket Geometry and of the Ligand Configuration

Journal: Letters in Drug Design & Discovery
Volume: 9,Issue: 1
Page: 54-62
Authors: Claire Colas, Xavier Brotel, Nathalie Duclert-Savatier, Michael Nilges, Delphine Joseph and Therese E. Malliavin

Role of Acetylcholinesterase Inhibitors in the Metabolism of Amyloid Precursor Protein

Journal: Current Drug Target -CNS & Neurological Disorders
Volume: 2,Issue: 3
Page: 163-171
Authors: M. Pakaski and P. Kasa

Autoantibodies and Sjogren’s Syndrome: A Physiologist’s Perspective

Journal: Current Pharmaceutical Biotechnology
Volume: 13,Issue: 10
Page: 2063-2070
Authors: Peter M. Smith and Luke J. Dawson

Acetylcholinesterase Inhibitors: Pharmacology and Toxicology

Journal: Current Neuropharmacology
Volume: 11,Issue: 3
Page: 315-335
Authors: Mirjana B. Colovic, Danijela Z. Krstic, Tamara D. Lazarevic-Pasti, Aleksandra M. Bondzic and Vesna M. Vasic

Mouse Models of Myasthenia Gravis

Journal: Current Pharmaceutical Design
Volume: 21,Issue: 18
Page: 2468-2486
Authors: Joanne Ban and William D. Phillips

Alzheimer's disease: Targeting the Cholinergic System

Journal: Current Neuropharmacology
Volume: 14,Issue: 1
Page: 101-115
Authors: Talita H. Ferreira-Vieira, Isabella M. Guimaraes, Flavia R. Silva and Fabiola M. Ribeiro

Beyond Acetylcholinesterase Inhibitors: Novel Cholinergic Treatments for Alzheimer’s Disease

Journal: Current Alzheimer Research
Volume: 14,Issue: 4
Page: 377-392
Authors: Asante R. Kamkwalala and Paul A. Newhouse

Mechanism of Organophosphates (Nerve Gases and Pesticides) and Antidotes: Electron Transfer and Oxidative Stress

Journal: Current Medicinal Chemistry
Volume: 10,Issue: 24
Page: 2705-2709
Authors: Peter Kovacic

New Anti-Alzheimer Drugs from Biodiversity: The Role of the Natural Acetylcholinesterase Inhibitors

Journal: Mini-Reviews in Medicinal Chemistry
Volume: 5,Issue: 10
Page: 915-926
Authors: Claudio Viegas Jr., Vanderlan d. S. Bolzani, Eliezer J. Barreiro and Carlos A. Manssour Fraga

Pharmacological Therapy of Parkinsons Disease: Current Options and New Avenues

Journal: Recent Patents on CNS Drug Discovery
Volume: 5,Issue: 3
Page: 221-238
Authors: Nicola Simola, Annalisa Pinna and Sandro Fenu

Imaging Endogenous Neurotransmitters In Vivo with Positron Emission Tomography Displacement Studies

Journal: Current Psychopharmacology
Volume: 1,Issue: 1
Page: 29-43
Authors: Giampaolo Tomasi

New Insights on Dimethylaminoethanol (DMAE) Features as a Free Radical Scavenger

Journal: Drug Metabolism Letters
Volume: 6,Issue: 1
Page: 54-59
Authors: Gabriela Malanga, Maria Belen Aguiar, Hugo D. Martinez and Susana Puntarulo

Selected PET Radioligands for Ion Channel Linked Neuroreceptor Imaging: Focus on GABA, NMDA and nACh Receptors

Journal: Current Topics in Medicinal Chemistry
Volume: 16,Issue: 16
Page: 1830-1842
Authors: Alina Kassenbrock, Neil Vasdev and Steven H. Liang

Bispidine as a Privileged Scaffold

Journal: Current Topics in Medicinal Chemistry
Volume: 16,Issue: 11
Page: 1314-1342
Authors: Isabelle Tomassoli and Daniela Gündisch

Microglia-Neuron Interaction in Inflammatory and Degenerative Diseases: Role of Cholinergic and Noradrenergic Systems

Journal: CNS & Neurological Disorders - Drug Targets
Volume: 6,Issue: 6
Page: 388-397
Authors: L. Minghetti, D. Carnevale and R. De Simone

Treatment of Disorders Characterized by Reversible Airway Obstruction in Childhood: are Anti-cholinergic Agents the Answer?

Journal: Current Pharmaceutical Design
Volume: 18,Issue: 21
Page: 3061-3085
Authors: Annabelle Quizon, Andrew A. Colin, Umberto Pelosi and Giovanni A. Rossi

Antioxidant Activity of Galantamine and Some of its Derivatives

Journal: Current Medicinal Chemistry
Volume: 20,Issue: 36
Page: 4595-4608
Authors: D. Tsvetkova, D. Obreshkova, D. Zheleva – Dimitrova and L. Saso

Endothelial Function: A Surrogate Endpoint in Cardiovascular Studies?

Journal: Current Pharmaceutical Design
Volume: 13,Issue: 17
Page: 1741-1750
Authors: Matthias Frick and Franz Weidinger

An Overview of the Current and Novel Drugs for Alzheimers Disease with Particular Reference to Anti-Cholinesterase Compounds

Journal: Current Pharmaceutical Design
Volume: 10,Issue: 25
Page: 3121-3130
Authors: Marcela Colombres, Juan Paulo Sagal and Nibaldo C. Inestrosa

(Neuro)Transmitter Systems in Circulating Immune Cells: A Target of Immunopharmacological Interventions?

Journal: Current Medicinal Chemistry
Volume: 15,Issue: 30
Page: 3228-3247
Authors: Seyed Khosrow Tayebati and Francesco Amenta

Current Clinical Applications of Botulinum Toxin

Journal: Current Pharmaceutical Design
Volume: 15,Issue: 31
Page: 3671-3680
Authors: Daniel D. Truong, Andrea Stenner and Gerhard Reichel

Macrophage-Assisted Inflammation and Pharmacological Regulation of the Cholinergic Anti-Inflammatory Pathway

Journal: Current Medicinal Chemistry
Volume: 18,Issue: 4
Page: 539-551
Authors: M. Pohanka, S. Snopkova, K. Havlickova, P. Bostik, Z. Sinkorova, J. Fusek, K. Kuca and Jiri Pikula

Neuroprotective Properties of Nicotine

Journal: Current Medicinal Chemistry
Volume: 19,Issue: 2
Page: 292-297
Authors: M. Sieber

Structure-Activity Studies on Alpha-Conotoxins

Journal: Current Pharmaceutical Design
Volume: 17,Issue: 38
Page: 4226-4241
Authors: Markus Muttenthaler, Kalyana B. Akondi and Paul F. Alewood

Screening for New Agonists Against Alzheimers Disease

Journal: Medicinal Chemistry
Volume: 3,Issue: 5
Page: 488-493
Authors: Huiqin Zheng, Dong-Qing Wei, Rui Zhang, Chunfang Wang, Huachun Wei and Kuo-Chen Chou

Cholinergic Agonists and the Treatment of Alzheimers Disease

Journal: Current Topics in Medicinal Chemistry
Volume: 2,Issue: 4
Page: 353-358
Authors: William S. Messer and Jr.

From Protein to Peptides: a Spectrum of Non-Hydrolytic Functions of Acetylcholinesterase

Journal: Protein & Peptide Letters
Volume: 19,Issue: 2
Page: 165-172
Authors: Amy C. Halliday and Susan A. Greenfield

Novel Targets for Drugs in Schizophrenia

Journal: CNS & Neurological Disorders - Drug Targets
Volume: 6,Issue: 4
Page: 265-272
Authors: J.M. Stone and L.S. Pilowsky

Endocannabinoids and Drug Dependence

Journal: Current Drug Target -CNS & Neurological Disorders
Volume: 4,Issue: 6
Page: 643-655
Authors: Daniela Parolaro, Daniela Vigano and Tiziana Rubino

Cardiovascular Effects of the Phytoestrogen Genistein

Journal: Current Medicinal Chemistry-Cardiovascular & Hematological Agents
Volume: 2,Issue: 2
Page: 179-186
Authors: Domenica Altavilla, Alessandra Crisafulli, Herbert Marini, Maria Esposito, Rosario D'Anna, Francesco Corrado, Alessandra Bitto and Francesco Squadrito

Targeting Neuronal Nicotinic Receptors: a Path to New Therapies

Journal: Current Drug Target -CNS & Neurological Disorders
Volume: 1,Issue: 4
Page: 349-357
Authors: Merouane Bencherif and Jeffrey D. Schmitt

The Sea Urchin, Paracentrotus lividus, as a Model to Investigate the Onset of Molecules Immunologically Related to the α-7 Subunit of Nicotinic Receptors During Embryonic and Larval Development

Journal: Current Drug Targets
Volume: 13,Issue: 5
Page: 587-593
Authors: Maria Grazia Aluigi, Alberto Diaspro, Paola Ramoino, Patrizia Russo and Carla Falugi

Recent Advances in Potential Therapeutic Drugs for Cognitive Impairment in Schizophrenia

Journal: Current Psychiatry Reviews
Volume: 8,Issue: 2
Page: 140-150
Authors: Taisuke Yoshida, Masaomi Iyo and Kenji Hashimoto

Treating Impaired Cognition in Schizophrenia

Journal: Current Pharmaceutical Biotechnology
Volume: 13,Issue: 8
Page: 1587-1594
Authors: H. M. Ibrahim and C. A. Tamminga

An Introduction to the Nutrition and Metabolism of Choline

Journal: Central Nervous System Agents in Medicinal Chemistry
Volume: 12,Issue: 2
Page: 100-113
Authors: Clarie B. Hollenbeck

Cholinergic Modulation by Opioid Receptor Ligands: Potential Application to Alzheimer’s Disease

Journal: Mini-Reviews in Medicinal Chemistry
Volume: 13,Issue: 3
Page: 456-466
Authors: William C. Motel, Andrew Coop and Christopher W. Cunningham

Psychoimmunological Analysis of Cancer Patients: Correlation with the Prognosis

Journal: Current Aging Science
Volume: 5,Issue: 3
Page: 263-272
Authors: Giuseppina Messina, Paolo Lissoni and Franco Rovelli

Cholinergic Drugs as Therapeutic Tools in Inflammatory Diseases: Participation of Neuronal and Non-Neuronal Cholinergic Systems.

Journal: Anti-Inflammatory & Anti-Allergy Agents in Medicinal Chemistry
Volume: 12,Issue: 2
Page: 109-116
Authors: María Elena Sales

Nature: A Substantial Source of Auspicious Substances with Acetylcholinesterase Inhibitory Action

Journal: Current Neuropharmacology
Volume: 11,Issue: 4
Page: 379-387
Authors: Ilkay Erdogan Orhan

Natural AChE Inhibitors from Plants and their Contribution to Alzheimer’s Disease Therapy

Journal: Current Neuropharmacology
Volume: 11,Issue: 4
Page: 388-413
Authors: Ana Paula Murray, Maria Belen Faraoni, María Julia Castro, Natalia Paola Alza and Valeria Cavallaro

Design and Synthesis of New Dual Binding Site Cholinesterase Inhibitors: in vitro Inhibition Studies with in silico Docking

Journal: Letters in Drug Design & Discovery
Volume: 11,Issue: 3
Page: 331-338
Authors: Muhammad Yar, Marek Bajda, Rana Atif Mehmood, Lala Rukh Sidra, Nisar Ullah, Lubna Shahzadi, Muhammad Ashraf, Tayaba Ismail, Sohail Anjum Shahzad, Zulfiqar Ali Khan, Syed Ali Raza Naqvi and Nasir Mahmood

Current Acetylcholinesterase-Inhibitors: A Neuroinformatics Perspective

Journal: CNS & Neurological Disorders - Drug Targets
Volume: 13,Issue: 3
Page: 391-401
Authors: Sibhghatulla Shaikh, Anupriya Verma, Saimeen Siddiqui, Syed S. Ahmad, Syed M.D. Rizvi, Shazi Shakil, Deboshree Biswas, Divya Singh, Mohmmad H. Siddiqui, Shahnawaz Shakil, Shams Tabrez and Mohammad A. Kamal

Computational Evidence for the Reactivation Process of Human Acetylcholinesterase Inhibited by Carbamates

Journal: Combinatorial Chemistry & High Throughput Screening
Volume: 17,Issue: 6
Page: 554-564
Authors: Karina Silvia Matos, Elaine F. F. da Cunha, Ruben Abagyan and Teodorico C. Ramalho

Scopolamine and Depression: A Role for Muscarinic Antagonism?

Journal: CNS & Neurological Disorders - Drug Targets
Volume: 13,Issue: 4
Page: 673-683
Authors: Helge Hasselmann

Antiepileptic Drugs Based on the α-Substituted Amide Group Pharmacophore: From Chemical Crystallography to Molecular Pharmaceutics

Journal: Current Pharmaceutical Design
Volume: 22,Issue: 32
Page: 5029-5040
Authors: Arcadius V. Krivoshein

Fluparoxan: A Comprehensive Review of its Discovery, Adrenergic and CNS Activity and Treatment of Cognitive Dysfunction in Central Neurodegenerative Diseases

Journal: Mini-Reviews in Medicinal Chemistry
Volume: 17,Issue: 7
Page: 572-582
Authors: Alan D. Borthwick*

Alzheimer’s Drug Discovery Maze: A Snap View of the Past Decade’s Diverse Pharmacological Targets for the Disorder

Journal: Mini-Reviews in Medicinal Chemistry
Volume: 17,Issue: 3
Page: 305-318
Authors: Donald Sikazwe, Raghunandan Yendapally, Sushma Ramsinghani and Malik Khan

Imaging of Muscarinic Receptors in the Central Nervous System

Journal: Current Pharmaceutical Design
Volume: 12,Issue: 30
Page: 3901-3913
Authors: W. C. Eckelman

Pharmacological Overview and Future Perspectives of Cholinergic Therapy in Alzheimers Disease

Journal: Current Drug Therapy
Volume: 4,Issue: 1
Page: 65-72
Authors: Hiroo Ogura

Organic Cation Transporters: Physiology, Toxicology and Special Focus on Ethidium as a Novel Substrate

Journal: Current Drug Metabolism
Volume: 10,Issue: 6
Page: 617-631
Authors: Wing-Kee Lee, Natascha A. Wolff and Frank Thevenod

Physiological Roles of Neuronal Nicotinic Receptors Subtypes: New Insights on the Nicotinic Modulation of Neurotransmitter Release, Synaptic Transmission and Plasticity

Journal: Current Topics in Medicinal Chemistry
Volume: 4,Issue: 3
Page: 283-297
Authors: E. Sher, Y. Chen, T.J.W. Sharples, L.M. Broad, G. Benedetti, R. Zwart, G.I. McPhie, K.H. Pearson, T. Baldwinson and G. De Filippi

Alpha Beta-Hydrolase Fold Enzymes Structures, Functions and Mechanisms

Journal: Current Protein & Peptide Science
Volume: 1,Issue: 2
Page: 209-235
Authors: Mats Holmquist

Involvement of Serotonin in the Acute Dependence Produced by μ, and K Opioid Agonists

Journal: Letters in Drug Design & Discovery
Volume: 6,Issue: 1
Page: 8-12
Authors: Anna Capasso

The Role of Extracellular Adenosine in Chemical Neurotransmission in the Hippocampus and Basal Ganglia: Pharmacological and Clinical Aspects

Journal: Current Topics in Medicinal Chemistry
Volume: 11,Issue: 8
Page: 1034-1046
Authors: Beata Sperlagh and E. Sylvester Vizi

Expression, Purification and Development of Neutralizing Antibodies from Synthetic BoNT/B LC and Its Application in Detection of Botulinum Toxin Serotype B

Journal: Protein & Peptide Letters
Volume: 19,Issue: 3
Page: 288-298
Authors: S. Ponmariappan, Swati Jain, Richa Sijoria, Arvind Tomar and Om Kumar

Current Concepts on Selected Plant Secondary Metabolites With Promising Inhibitory Effects Against Enzymes Linked to Alzheimer’s Disease

Journal: Current Medicinal Chemistry
Volume: 19,Issue: 14
Page: 2252-2261
Authors: I. Erdogan Orhan

Choline Nutrition Programs Brain Development Via DNA and Histone Methylation

Journal: Central Nervous System Agents in Medicinal Chemistry
Volume: 12,Issue: 2
Page: 82-94
Authors: Jan Krzysztof Blusztajn and Tiffany J. Mellott

Cerebrovascular and Blood-Brain Barrier Morphology in Spontaneously Hypertensive Rats: Effect of Treatment with Choline Alphoscerate

Journal: CNS & Neurological Disorders - Drug Targets
Volume: 14,Issue: 3
Page: 421-429
Authors: Seyed Khosrow Tayebati, Francesco Amenta and Daniele Tomassoni

Pharmacological Evaluation of Antiasthmatic Activity of Myrica nagi Bark Extracts

Journal: Anti-Inflammatory & Anti-Allergy Agents in Medicinal Chemistry
Volume: 15,Issue: 2
Page: 145-152
Authors: Rinu K. Rana and Rakesh K. Patel

A Qualitative and Quantitative Study of the Innervation of the Human Non Pregnant Uterus

Journal: Current Protein & Peptide Science
Volume: 18,Issue: 2
Page: 140-148
Authors: Silvia Di Tommaso, Carlo Cavallotti, Antonio Malvasi, Daniele Vergara, Antonio Rizzello, Francesco De Nuccio and Andrea Tinelli

Acetylcholinesterase Inhibitors and Drugs Acting on Muscarinic Receptors- Potential Crosstalk of Cholinergic Mechanisms During Pharmacological Treatment

Journal: Current Neuropharmacology
Volume: 15,Issue: 4
Page: 637-653
Authors: Ondrej Soukup, Michael Winder, Uday Kumar Killi, Vladimir Wsol, Daniel Jun, Kamil Kuca* and Gunnar Tobin*

Gq protein-Coupled Receptors as Targets for Anesthetics

Journal: Current Pharmaceutical Design
Volume: 12,Issue: 15
Page: 1931-1937
Authors: Kouichiro Minami and Yasuhito Uezono

Neurochemistry of the Nucleus Accumbens and its Relevance to Depression and Antidepressant Action in Rodents

Journal: Current Neuropharmacology
Volume: 4,Issue: 4
Page: 277-291
Authors: Yukihiko Shirayama and Shigeyuki Chaki

The Neurobiological Bases for the Pharmacotherapy of Nicotine Addiction

Journal: Current Pharmaceutical Design
Volume: 13,Issue: 12
Page: 1269-1284
Authors: Vincenzo Di Matteo, Massimo Pierucci, Giuseppe Di Giovanni, Arcangelo Benigno and Ennio Esposito

Effects of Nicotine During Pregnancy: Human and Experimental Evidence

Journal: Current Neuropharmacology
Volume: 5,Issue: 3
Page: 213-222
Authors: R. Wickstrom

Selective Targeting of Muscarinic Receptors: Novel Therapeutic Approaches for Psychotic Disorders

Journal: Current Neuropharmacology
Volume: 3,Issue: 1
Page: 63-71
Authors: Cyrille Sur and Gene G. Kinney

New Classes of AChE Inhibitors with Additional Pharmacological Effects of Interest for the Treatment of Alzheimers Disease

Journal: Current Pharmaceutical Design
Volume: 10,Issue: 25
Page: 3177-3184
Authors: M. Villarroya, A. G. García and J. L. Marco

Tachykinins and Tachykinin Receptors: Structure and Activity Relationships

Journal: Current Medicinal Chemistry
Volume: 11,Issue: 15
Page: 2045-2081
Authors: T. A. Almeida, J. Rojo, P. M. Nieto, F. M. Pinto, M. Hernandez, J. D. Martín and M. L. Candenas

Disease Modifying Therapeutic Strategies in Alzheimers Disease Targeting the Amyloid Cascade

Journal: Current Neuropharmacology
Volume: 2,Issue: 3
Page: 295-307
Authors: Christian Czech and Celine Adessi

Myostimulating Effect of the Aqueous Extract of Khaya senegalensis (Desr) A. Juss.(Meliaceae) in Isolated Taenia caeci Contractile Activity

Journal: Current Bioactive Compounds
Volume: 3,Issue: 4
Page: 291-294
Authors: A. Souza, J. Aka Kadjo, J. C. Abo Kouakou, Y. Datte-Jacques, F. Traore and B. M'Batchi

Current Therapeutic Options for Alzheimers Disease

Journal: Current Genomics
Volume: 8,Issue: 8
Page: 550-558
Authors: Alberto Lleo

Natural Products and their Derivatives as Cholinesterase Inhibitors in the Treatment of Neurodegenerative Disorders: An Update

Journal: Current Medicinal Chemistry
Volume: 15,Issue: 12
Page: 1209-1228
Authors: Monica Rosa Loizzo, Rosa Tundis, Federica Menichini and Francesco Menichini

Endothelial Dysfunction in the Hypertensive State: Mechanisms of Hypertensive Cardiovascular Complications

Journal: Current Hypertension Reviews
Volume: 4,Issue: 4
Page: 303-312
Authors: Allison B. Reiss, Arup K. Nath, Bipasha Nath and Kamran Anwar

The Application of PET Technique for the Development and Evaluation of Novel Antipsychotics

Journal: Current Pharmaceutical Design
Volume: 16,Issue: 3
Page: 371-377
Authors: Akihiro Takano

Simple Choline Esters as Potential Anti-Alzheimer Agents

Journal: Current Pharmaceutical Design
Volume: 16,Issue: 6
Page: 692-697
Authors: Stefano Alcaro, Rosaria Arcone, Giosue Costa, Daniela De Vita, Michelangelo Iannone, Francesco Ortuso, Antonio Procopio, Raffaele Pasceri, Domenicantonio Rotiroti and Luigi Scipione

Structure-Activity Relationship of Quaternary Acetylcholinesterase Inhibitors – Outlook for Early Myasthenia Gravis Treatment

Journal: Current Medicinal Chemistry
Volume: 17,Issue: 17
Page: 1810-1824
Authors: M. Komloova, K. Musilek, M. Dolezal, F. Gunn-Moore and K. Kuca

Turning the Clock Ahead: Potential Preclinical and Clinical Neuropharmacological Targets for Alcohol Dependence

Journal: Current Pharmaceutical Design
Volume: 16,Issue: 19
Page: 2159-2181
Authors: Lorenzo Leggio, Silvia Cardone, Anna Ferrulli, George A. Kenna, Marco Diana, Robert M. Swift and Giovanni Addolorato

Antihypertensive Properties of Angiotensin-Converting Enzyme Inhibitors (ACEI) Independent of the Renin-Angiotensin System

Journal: Current Hypertension Reviews
Volume: 6,Issue: 3
Page: 180-185
Authors: Therezinha Bandiera Paiva, Jamille Cristina Rocco Bravo, Nelson Carvalho Farias and Teresa Feres

Structural Determinants of the Multifunctional Profile of Dual Binding Site Acetylcholinesterase Inhibitors as Anti-Alzheimer Agents

Journal: Current Pharmaceutical Design
Volume: 16,Issue: 25
Page: 2818-2836
Authors: Carles Galdeano, Elisabet Viayna, Pau Arroyo, Axel Bidon-Chanal, J. Ramon Blas, Diego Munoz-Torrero and F. Javier Luque

The Neuropharmacology of Implicit Learning

Journal: Current Neuropharmacology
Volume: 8,Issue: 4
Page: 367-381
Authors: Julia Udden, Vasiliki Folia and Karl Magnus Petersson

In Silico Methods to Assist Drug Developers in Acetylcholinesterase Inhibitor Design

Journal: Current Medicinal Chemistry
Volume: 18,Issue: 8
Page: 1122-1136
Authors: J. A. Bermudez-Lugo, M. C. Rosales-Hernandez, O. Deeb, J. Trujillo-Ferrara and J. Correa-Basurto

Kynurenine Metabolites and Migraine: Experimental Studies and Therapeutic Perspectives

Journal: Current Neuropharmacology
Volume: 9,Issue: 2
Page: 376-387
Authors: Annamaria Fejes, Arpad Pardutz, Jozsef Toldi and Laszlo Vecsei

Pharmacological Approaches of Alzheimer's Disease: An Update

Journal: Current Drug Therapy
Volume: 6,Issue: 3
Page: 186-196
Authors: Safia A. Khan, Kamsagara L. Krishna, Ajay J. Parikh, Priya and Sudha R. Dodi

Botulinum Toxin a in Prostate Disease: A Venom from Bench to Bed-Side

Journal: Current Drug Delivery
Volume: 9,Issue: 1
Page: 85-94
Authors: Luigi Mearini and Antonella Giannantoni

Alterations in the Vascular Reactivity of Aorta in the Early and Late Phase of Adjuvant-Induced Arthritis in Rat

Journal: Vascular Disease Prevention
Volume: 4,Issue: 1
Page: 11-19
Authors: Buket Demirci, Aysegul Uysal and Sibel Ulker

Novel Anti-Arrhythmic Drugs for Atrial Fibrillation Management

Journal: Current Vascular Pharmacology
Volume: 5,Issue: 3
Page: 185-194
Authors: Joachim R. Ehrlich, Stanley Nattel and Stefan H. Hohnloser

Manipulation of Signal Transduction by Botulinum Neurotoxins and their Derivatives

Journal: Current Signal Transduction Therapy
Volume: 2,Issue: 3
Page: 221-225
Authors: John A. Chaddock and Keith A. Foster

Cholinesterases: Roles in the Brain During Health and Disease

Journal: Current Alzheimer Research
Volume: 2,Issue: 3
Page: 307-318
Authors: Clive G. Ballard, Nigel H. Greig, Angela L. Guillozet-Bongaarts, Albert Enz and Sultan Darvesh

Mapping of the Benzodiazepine Recognition Site on GABA-A Receptors

Journal: Current Topics in Medicinal Chemistry
Volume: 2,Issue: 8
Page: 833-839
Authors: Erwin Sigel

Medicinal Chemistry and Molecular Pharmacology of GABA-C Receptors

Journal: Current Topics in Medicinal Chemistry
Volume: 2,Issue: 8
Page: 903-913
Authors: Graham A.R. Johnston

Histamine H3 Antagonists as Wake-Promoting and Pro-Cognitive Agents

Journal: Current Topics in Medicinal Chemistry
Volume: 8,Issue: 11
Page: 988-1002
Authors: Emily M. Stocking and Michael A. Letavic

Antibodies Against Muscarinic Receptors in Breast Cancer: Agonizing Tumor Growth

Journal: Current Immunology Reviews
Volume: 4,Issue: 3
Page: 176-182
Authors: Gabriel L. Fiszman and Maria E. Sales

Contemporary Anticholinesterase Pharmaceuticals of Natural Origin and Their Synthetic Analogues for the Treatment of Alzheimers Disease

Journal: Recent Patents on CNS Drug Discovery
Volume: 4,Issue: 1
Page: 43-51
Authors: Gurdal Orhan, Ilkay Orhan, Nese Subutay-Oztekin, Fikri Ak and Bilge Sener

α 2-Adrenoceptor Antagonist SL84.0418 Involvement in the Development of Opioid Withdrawal

Journal: Letters in Drug Design & Discovery
Volume: 6,Issue: 2
Page: 159-162
Authors: Anna Capasso and Chiara Gallo

Highly Pure Phospholipids Based Brain Docosahexaenoic Acid Transporters

Journal: Recent Patents on CNS Drug Discovery
Volume: 5,Issue: 2
Page: 135-146
Authors: Su Chen

Novel Agents for the Acute Conversion of Atrial Fibrillation: Focus on Vernakalant

Journal: Recent Patents on Cardiovascular Drug Discovery (Discontinued)
Volume: 6,Issue: 1
Page: 1-8
Authors: Pio Cialdella, Daniela Pedicino and Pasquale Santangeli

The Evolution of Histamine H3 Antagonists/Inverse Agonists

Journal: Current Topics in Medicinal Chemistry
Volume: 11,Issue: 6
Page: 648-660
Authors: Evan P. Lebois, Carrie K. Jones and Craig W. Lindsley

Design, Synthesis and Interaction at the Vesicular Monoamine Transporter-2 of Lobeline Analogs: Potential Pharmacotherapies for the Treatment of Psychostimulant Abuse

Journal: Current Topics in Medicinal Chemistry
Volume: 11,Issue: 9
Page: 1103-1127
Authors: Peter A. Crooks, Guangrong Zheng, Ashish P. Vartak, John P. Culver, Fang Zheng, David B. Horton and Linda P. Dwoskin

Analgesic and Antineuropathic Drugs Acting Through Central Cholinergic Mechanisms

Journal: Recent Patents on CNS Drug Discovery
Volume: 6,Issue: 2
Page: 119-140
Authors: Alessandro Bartolini, Lorenzo Di Cesare Mannelli and Carla Ghelardini

Venom Peptide Modulators of the Immune System

Journal: Inflammation & Allergy-Drug Targets (Discontinued)
Volume: 10,Issue: 5
Page: 399-410
Authors: Marco C. Inserra and Richard J. Lewis

GPE and GPE Analogues as Promising Neuroprotective Agents

Journal: Mini-Reviews in Medicinal Chemistry
Volume: 12,Issue: 1
Page: 13-23
Authors: I. Cacciatore, C. Cornacchia, L. Baldassarre, E. Fornasari, A. Mollica, A. Stefanucci and F. Pinnen

Neuropeptides as Possible Targets in Sleep Disorders: Special Emphasis on Hypocretin-Deficient Narcolepsy

Journal: CNS & Neurological Disorders - Drug Targets
Volume: 6,Issue: 1
Page: 45-62
Authors: Nobuhiro Fujiki and Seiji Nishino

The Benzodiazepine Recognition Site on GABAA Receptors

Journal: Medicinal Chemistry Reviews - Online (Discontinued)
Volume: 2,Issue: 3
Page: 251-256
Authors: Erwin Sigel

Knock-out and Knock-in Mice to Investigate the Role of Nicotinic Receptors in the Central Nervous System

Journal: Current Drug Target -CNS & Neurological Disorders
Volume: 1,Issue: 4
Page: 319-330
Authors: N. Champtiaux and J. P. Changeux

Acetylcholinesterase: Mechanism of Catalysis and Inhibition

Journal: Current Medicinal Chemistry-Central Nervous System Agents
Volume: 1,Issue: 2
Page: 155-170
Authors: V. Tougu

Mechanistic Systems Biology of Inflammatory Gene Expression in Airway Smooth Muscle as Tool for Asthma Drug Development

Journal: Current Drug Discovery Technologies
Volume: 5,Issue: 4
Page: 279-288
Authors: Chi-Ming Hai

Neuronal Nicotinic Receptors as Brain Targets for Pharmacotherapy of Drug Addiction

Journal: CNS & Neurological Disorders - Drug Targets
Volume: 7,Issue: 5
Page: 422-441
Authors: Shafiqur Rahman, Gretchen Y. Lopez-Hernandez, William A. Corrigall and Roger L. Papke

Mechanisms of Sleep-Wake Cycle Modulation

Journal: CNS & Neurological Disorders - Drug Targets
Volume: 8,Issue: 4
Page: 245-253
Authors: Eric Murillo-Rodriguez, Oscar Arias-Carrion, Katya Sanguino-Rodriguez, Mauricio Gonzalez-Arias and Reyes Haro

Neuropharmacology of the Interoceptive Stimulus Properties of Nicotine

Journal: Current Drug Abuse Reviews
Volume: 2,Issue: 3
Page: 243-255
Authors: Thomas E. Wooters, Rick A. Bevins and Michael T. Bardo

Treating Schizophrenia: Novel Targets for the Cholinergic System

Journal: CNS & Neurological Disorders - Drug Targets
Volume: 9,Issue: 2
Page: 241-256
Authors: T.T. Money, E. Scarr, M. Udawela, A.S. Gibbons, W.J. Jeon, M.S. Seo and B. Dean

Targeting Nicotinic Receptors for Parkinson's Disease Therapy

Journal: CNS & Neurological Disorders - Drug Targets
Volume: 10,Issue: 6
Page: 651-658
Authors: Maryka Quik, Tanuja Bordia, Luping Huang and Xiomara Perez

Treatment of Alzheimers Disease: Symptomatic and Disease-Modifying Approaches

Journal: Current Aging Science
Volume: 3,Issue: 1
Page: 46-56
Authors: Daniela Galimberti and Elio Scarpini

Kinetics of In Vitro Inhibition of Acetylcholinesterase by Nineteen New Carbamates

Journal: Current Enzyme Inhibition
Volume: 7,Issue: 4
Page: 236-243
Authors: Marketa Kovarova, Mahmud T.H. Khan, Karel Komers, Patrik Parík, Alexander Cegan and Martina Zatloukalova

Novel Approaches to Study the Involvement of α7-nAChR in Human Diseases

Journal: Current Drug Targets
Volume: 13,Issue: 5
Page: 579-586
Authors: Eleonora Palma, Luca Conti, Cristina Roseti and Cristina Limatola

Pitavastatin Improves Endothelial Function and Glucose Metabolism in Ovariectomized Mice

Journal: Immunology‚ Endocrine & Metabolic Agents in Medicinal Chemistry
Volume: 12,Issue: 1
Page: 29-33
Authors: Hironori Nakagami, Mariana Kiomy Osako, Natsuki Yasumasa, Munehisa Shimamura, Mariko Kyutoku, Futoshi Nakagami, Hiroshi Koriyama, Hideki Tomioka, Tomohiro Katsuya and Ryuichi Morishita

Basic Sleep Mechanisms: An Integrative Review

Journal: Central Nervous System Agents in Medicinal Chemistry
Volume: 12,Issue: 1
Page: 38-54
Authors: Eric Murillo-Rodriguez, Oscar Arias-Carrion, Abraham Zavala-Garcia, Andrea Sarro-Ramirez, Salvador Huitron-Resendiz and Gloria Arankowsky-Sandoval

A Fatal Outcome After Unintentional Overdosing of Rivastigmine Patches

Journal: Current Drug Safety
Volume: 7,Issue: 1
Page: 30-32
Authors: Henrik Lovborg, Anna K Jonsson and Staffan Hagg

Cholinergic Receptor System as a Target for Treating Alcohol Abuse and Dependence

Journal: Recent Patents on CNS Drug Discovery
Volume: 7,Issue: 2
Page: 145-150
Authors: Shafiqur Rahman and Mark A. Prendergast

Targeting Neuronal Nicotinic Receptors in Cancer: New Ligands and Potential Side-Effects

Journal: Recent Patents on Anti-Cancer Drug Discovery
Volume: 8,Issue: 1
Page: 38-52
Authors: Paola Ambrosi and Andrea Becchetti

Nicotine and Gastrointestinal Disorders: Its Role in Ulceration and Cancer Development

Journal: Current Pharmaceutical Design
Volume: 19,Issue: 1
Page: 5-10
Authors: Kent-Man Chu, Chi H. Cho and Vivian Y. Shin

Alteration of Cholinergic System in Keratinocytes Cells Produces Acantholysis: A Possible Use of Cholinergic Drugs in Pemphigus Vulgaris

Journal: Anti-Inflammatory & Anti-Allergy Agents in Medicinal Chemistry
Volume: 11,Issue: 3
Page: 238-242
Authors: Luca Fania, Anna Zampetti, Giuseppe Guerriero and Claudio Feliciani

Neurotransmitters, Psychotropic Drugs and Microglia: Clinical Implications for Psychiatry

Journal: Current Medicinal Chemistry
Volume: 20,Issue: 3
Page: 331-344
Authors: T. A. Kato, Y. Yamauchi, H. Horikawa, A. Monji, Y. Mizoguchi, Y. Seki, K. Hayakawa, H. Utsumi and S. Kanba

Rosuvastatin Ameliorates Obesity and Proteinuria in Zucker Diabetic Fatty Rats

Journal: Immunology‚ Endocrine & Metabolic Agents in Medicinal Chemistry
Volume: 13,Issue: 2
Page: 144-149
Authors: Hironori Nakagami, Takashi Shimosato, Munehisa Shimamura and Ryuichi Morishita

Nicotinic Receptors as Therapeutic Targets for Drug Addictive Disorders

Journal: CNS & Neurological Disorders - Drug Targets
Volume: 12,Issue: 5
Page: 633-640
Authors: Shafiqur Rahman

Dual Inhibitors of Monoamine Oxidase and Cholinesterase for the Treatment of Alzheimer Disease

Journal: Current Topics in Medicinal Chemistry
Volume: 13,Issue: 14
Page: 1692-1706
Authors: Matilde Yanez and Dolores Vina

Muscarinic Activation Enhances the Anti-proliferative Effect of Paclitaxel in Murine Breast Tumor Cells

Journal: Anti-Cancer Agents in Medicinal Chemistry
Volume: 13,Issue: 8
Page: 1273-1279
Authors: Alejandro Javier Español, Guillermina Jacob, Ganna Dmytrenko and María Elena Sales

Choline Alphoscerate (Alpha-Glyceryl-Phosphoryl-Choline) An Old Choline- containing Phospholipid with a Still Interesting Profile As Cognition Enhancing Agent

Journal: Current Alzheimer Research
Volume: 10,Issue: 10
Page: 1070-1079
Authors: Enea Traini, Vincenzo Bramanti and Francesco Amenta

Going up in Smoke? A Review of nAChRs-based Treatment Strategies for Improving Cognition in Schizophrenia

Journal: Current Pharmaceutical Design
Volume: 20,Issue: 31
Page: 5077-5092
Authors: Douglas L. Boggs, Jon Carlson, Jose Cortes-Briones, John H. Krystal and D. Cyril D';Souza

Attentional Set-Shifting in Rodents: A Review of Behavioural Methods and Pharmacological Results

Journal: Current Pharmaceutical Design
Volume: 20,Issue: 31
Page: 5046-5059
Authors: David S. Tait, E. Alexander Chase and Verity J. Brown

Beyond Acetylcholinesterase Inhibitors for Treating Alzheimer's Disease: α7-nAChR Agonists in Human Clinical Trials

Journal: Current Pharmaceutical Design
Volume: 20,Issue: 38
Page: 6014-6021
Authors: Patrizia Russo, Alessandra Del Bufalo, Alessandra Frustaci, Massimo Fini and Alfredo Cesario

The Potential Role of Morus Alba Leaves Extract on the Brain of Mice Infected with Schistosoma Mansoni

Journal: CNS & Neurological Disorders - Drug Targets
Volume: 13,Issue: 9
Page: 1513-1519
Authors: Amira A. Bauomy

SAR Studies on Carboxylic Acid Series M1 Selective Positive Allosteric Modulators (PAMs)

Journal: Current Topics in Medicinal Chemistry
Volume: 14,Issue: 15
Page: 1738-1754
Authors: Scott D. Kuduk and Douglas C. Beshore

Interactions Between Cholinergic and Fibroblast Growth Factor Receptors in Brain Trophism and Plasticity

Journal: Current Protein & Peptide Science
Volume: 15,Issue: 7
Page: 691-702
Authors: Valentina Di Liberto, Giuseppa Mudo, Kjell Fuxe and Natale Belluardo

Recent Advances in Botulinum Neurotoxin Inhibitor Development

Journal: Current Topics in Medicinal Chemistry
Volume: 14,Issue: 18
Page: 2044-2061
Authors: Erkan Kiris, James C. Burnett, Christopher D. Kane and Sina Bavari

8-Hydroxyquinoline and Hydroxamic Acid Inhibitors of Botulinum Neurotoxin BoNT/A

Journal: Current Topics in Medicinal Chemistry
Volume: 14,Issue: 18
Page: 2094-2102
Authors: Tobin J. Dickerson, Garry R. Smith, Jeffrey C. Pelletier and Allen B. Reitz

Status of Acetylcholinesterase and Butyrylcholinesterase in Alzheimer's Disease and Type 2 Diabetes Mellitus

Journal: CNS & Neurological Disorders - Drug Targets
Volume: 13,Issue: 8
Page: 1432-1439
Authors: Gohar Mushtaq, Nigel H. Greig, Jalaluddin A. Khan and Mohammad A. Kamal

An Update of the Classical and Novel Methods Used for Measuring Fast Neurotransmitters During Normal and Brain Altered Function

Journal: Current Neuropharmacology
Volume: 12,Issue: 6
Page: 490-508
Authors: Victor Hugo Cifuentes Castro, Carmen Lucia Lopez Valenzuela, Juan Carlos Salazar Sanchez, Kenia Pardo Pena, Silvia J. Lopez Perez, Jorge Ortega Ibarra and Alberto Morales Villagran

Strategies of Functional Foods Promote Sleep in Human Being

Journal: Current Signal Transduction Therapy
Volume: 9,Issue: 3
Page: 148-155
Authors: Yawen Zeng, Jiazhen Yang, Juan Du, Xiaoying Pu, Xiaomen Yang, Shuming Yang and Tao Yang

Two Myomodulins Isolated from Central Nervous System of Northwest Pacific Sea Hare, Aplysia kurodai, and Their Activities on Other Mollusks

Journal: Protein & Peptide Letters
Volume: 22,Issue: 4
Page: 341-347
Authors: Chan-Hee Kim, Hye-Jin Go and Nam Gyu Park

Nicotine-Derived Compounds as Therapeutic Tools Against Post-Traumatic Stress Disorder

Journal: Current Pharmaceutical Design
Volume: 21,Issue: 25
Page: 3589-3595
Authors: George E Barreto, Alexander Yarkov, Marcos Avila-Rodriguez, Gjumrakch Aliev and Valentina Echeverria

Conotoxins: Structure, Therapeutic Potential and Pharmacological Applications

Journal: Current Pharmaceutical Design
Volume: 22,Issue: 5
Page: 582-589
Authors: Rafia Mir, Sajjad Karim, Mohammad Amjad Kamal, Cornelia M. Wilson and Zeenat Mirza

Autonomic Nervous System in Viral Myocarditis: Pathophysiology and Therapy

Journal: Current Pharmaceutical Design
Volume: 22,Issue: 4
Page: 485-498
Authors: Zheng Cheng, Ge Li-Sha and Li Yue-Chun

AChE Inhibition-based Multi-target-directed Ligands, a Novel Pharmacological Approach for the Symptomatic and Disease-modifying Therapy of Alzheimer’s Disease

Journal: Current Neuropharmacology
Volume: 14,Issue: 4
Page: 364-375
Authors: Yu Wang, Hao Wang and Hong-zhuan Chen

Serotonergic and Cholinergic Strategies as Potential Targets for the Treatment of Schizophrenia

Journal: Current Pharmaceutical Design
Volume: 22,Issue: 14
Page: 2093-2116
Authors: Agnieszka Nikiforuk

The Cholinergic System: An Emerging Drug Target for Schizophrenia

Journal: Current Pharmaceutical Design
Volume: 22,Issue: 14
Page: 2124-2133
Authors: Andrew Gibbons and Brian Dean

Neuroinflammation: A Therapeutic Target of Cotinine for the Treatment of Psychiatric Disorders?

Journal: Current Pharmaceutical Design
Volume: 22,Issue: 10
Page: 1324-1333
Authors: Valentina Echeverria, J. Alex Grizzell and George E. Barreto

A Link Between Nerve Growth Factor Metabolic Deregulation and Amyloid-β-Driven Inflammation in Down Syndrome

Journal: CNS & Neurological Disorders - Drug Targets
Volume: 15,Issue: 4
Page: 434-447
Authors: Maria Florencia Iulita, Filippo Caraci and Augusto Claudio Cuello

Pedunculopontine Nucleus Stimulation in Intractable Epilepsy: A Recent Patent on Deep Brain Stimulation Therapy

Journal: Recent Patents and Topics on Imaging
Volume: 5,Issue: 1
Page: 22-25
Authors: Harinder Jaseja

Searching for Therapeutics Against Botulinum Neurotoxins: A True Challenge for Drug Discovery

Journal: Current Topics in Medicinal Chemistry
Volume: 16,Issue: 21
Page: 2330-2349
Authors: Allen J. Duplantier, Christopher D. Kane and Sina Bavari

Drug Development of Small-Molecule Inhibitors of AD-Relevant Kinases as Novel Perspective Multitargeted Approach

Journal: Current Alzheimer Research
Volume: 13,Issue: 12
Page: 1330-1336
Authors: V. Tell, I. Hilbrich, M. Holzer, Frank Totzke, Christoph Schachtele, Inna Slynko, Wolfgang Sippl and A. Hilgeroth

Vagotomy and Gastric Tumorigenesis

Journal: Current Neuropharmacology
Volume: 14,Issue: 8
Page: 967-972
Authors: Hanne-Line Rabben, Chun-Mei Zhao, Yoku Hayakawa, Timothy C. Wang and Duan Chen

Elucidating Treatment of Alzheimer's Disease via Different Receptors

Journal: Current Topics in Medicinal Chemistry
Volume: 17,Issue: 12
Page: 1400-1407
Authors: Badar ul Islam, Mohd Shahnawaz Khan, Nasimudeen R. Jabir, Mohammad Amjad Kamal and Shams Tabrez

Smoking and Cognition

Journal: Current Drug Abuse Reviews
Volume: 9,Issue: 2
Page: 76-79
Authors: Marcela Waisman Campos, Debora Serebrisky and Joao Mauricio Castaldelli-Maia*

Cefixime-induced Oromandibular Dystonia in an Adult: A Case Report

Journal: Current Drug Safety
Volume: 12,Issue: 2
Page: 123-125
Authors: Lisa Mondet, Fanny Radoube, Valerie Gras* and Kamel Masmoudi

Alpha-7 Nicotinic Receptors in Nervous System Disorders: From Function to Therapeutic Perspectives

Journal: Central Nervous System Agents in Medicinal Chemistry
Volume: 17,Issue: 2
Page: 100-108
Authors: Antonella De Jaco, Laura Bernardini, Jessica Rosati and Ada Maria Tata*

A Current Perspective on the Inhibition of Cholinesterase by Natural and Synthetic Inhibitors

Journal: Current Drug Metabolism
Volume: 18,Issue: 2
Page: 96-111
Authors: Anzer A. Shah, Tanveer A. Dar, Parvaiz A. Dar, Showkat A. Ganie and Mohammad A. Kamal

Cholinergic Anti-inflammatory Pathway and Stroke

Journal: Current Drug Delivery
Volume: 14,Issue: 4
Page: 449-457
Authors: Kamil Duris, Jolana Lipkova and Michal Jurajda*

The Peptide Argireline-The Importance of Local Application on the Skin, in the Light of Current Knowledge

Journal: Letters in Drug Design & Discovery
Volume: 14,Issue: 10
Page: 1215-1220
Authors: Agnieszka Dana and Helena Rotsztejn*

Platelets: Their Potential Contribution to the Generation of Beta-amyloid Plaques in Alzheimer’s Disease

Journal: Current Neurovascular Research
Volume: 14,Issue: 3
Page: 290-298
Authors: Christian Humpel*

Editorial: Current Pro-Cognitive Therapeutic Strategies for Improved Pharmacological Treatment in Schizophrenia

Journal: Current Pharmaceutical Design
Volume: 20,Issue: 31
Page: 5045-5045
Authors: Marie-Louise G. Wadenberg

The Facilitatory Effect of Casearia sylvestris Sw. (guaçatonga) Fractions on the Contractile Activity of Mammalian and Avian Neuromuscular Apparatus

Journal: Current Pharmaceutical Biotechnology
Volume: 16,Issue: 5
Page: 468-481
Authors: Adriana C. Werner, Miriele C. Ferraz, Edson H. Yoshida, Natalia Tribuiani, Jean A.A. Gautuz, Monique N. Santana, Bruna A. Dezzotti, Vanessa G. de Miranda, Ameris L. Foramiglio, Sandro Rostelato-Ferreira, Renata V. da Silva Tavares, Stephen Hyslop and Yoko Oshima-Franco

Brain Neuronal Nicotinic Receptors as New Targets for Drug Discovery

Journal: Current Pharmaceutical Design
Volume: 12,Issue: 4
Page: 407-428
Authors: C. Gotti, L. Riganti, S. Vailati and F. Clementi

The Effect of Isoquinoline Alkaloids on Opiate Withdrawal

Journal: Current Medicinal Chemistry
Volume: 13,Issue: 7
Page: 807-812
Authors: A. Capasso, S. Piacente, N. D. Tommasi, L. Rastrelli and C. Pizza

Cholinesterase Inhibitors: From Weapons, to Pesticides, to Cognition Enhancing Drugs

Journal: Current Enzyme Inhibition
Volume: 2,Issue: 3
Page: 249-259
Authors: Francesco Amenta, Maria Antonietta Di Tullio, Lucilla Parnetti and Seyed Khosrow Tayebati

Structural Requirements of Acetylcholinesterase Reactivators

Journal: Mini-Reviews in Medicinal Chemistry
Volume: 6,Issue: 3
Page: 269-277
Authors: Kamil Kuca, Daniel Jun and Kamil Musilek

NO Chimeras as Therapeutic Agents in Alzheimers Disease

Journal: Current Alzheimer Research
Volume: 3,Issue: 3
Page: 237-245
Authors: Gregory R.J. Thatcher, Brian M. Bennett and James N. Reynolds

Airway Smooth Muscle Cell as Therapeutic Target of Inflammation

Journal: Current Medicinal Chemistry
Volume: 14,Issue: 1
Page: 67-76
Authors: Chi-Ming Hai

Modulation of Neurotransmitter Release by Carbon Monoxide at the Frog Neuro-Muscular Junction

Journal: Current Drug Metabolism
Volume: 8,Issue: 2
Page: 177-184
Authors: Guzel F. Sitdikova, Rustem R. Islamov, Marat A. Mukhamedyarov, Vladlena V. Permyakova, Andrey L. Zefirov and Andras Palotas

Synaptic Transmission at Functionally Identified Synapses in the Enteric Nervous System: Roles for Both Ionotropic and Metabotropic Receptors

Journal: Current Neuropharmacology
Volume: 5,Issue: 1
Page: 1-17
Authors: R. M. Gwynne and J. C. Bornstein

Recent Developments in Cholinesterases Inhibitors for Alzheimers Disease Treatment

Journal: Current Medicinal Chemistry
Volume: 14,Issue: 25
Page: 2654-2679
Authors: Anna Musial, Marek Bajda and Barbara Malawska

Sensory-Motor Integration in the Medial Medulla

Journal: Current Neuropharmacology
Volume: 3,Issue: 2
Page: 115-143
Authors: Yuan-Yang Lai and Jerome M. Siegel

Role of Kynurenines in the Central and Peripherial Nervous Systems

Journal: Current Neurovascular Research
Volume: 2,Issue: 3
Page: 249-260
Authors: Hajnalka Nemeth, Jozsef Toldi and Laszlo Vecsei

Ion Channels and Epilepsy

Journal: Current Pharmaceutical Design
Volume: 11,Issue: 15
Page: 1975-2003
Authors: J. A. Armijo, M. Shushtarian, E. M. Valdizan, A. Cuadrado, I. de las Cuevas and J. Adin

Acetylcholinesterase Imaging: Its Use in Therapy Evaluation and Drug Design

Journal: Current Pharmaceutical Design
Volume: 10,Issue: 13
Page: 1505-1517
Authors: Hitoshi Shinotoh, Kiyoshi Fukushi, Shin-ichiro Nagatsuka and Toshiaki Irie

Rationale for the Development of Cholinesterase Inhibitors as Anti- Alzheimer Agents

Journal: Current Pharmaceutical Design
Volume: 10,Issue: 25
Page: 3111-3119
Authors: D. K. Lahiri, J. T. Rogers, N. H. Greig and K. Sambamurti

Retrograde Modulation of Synaptic Transmission Mediated by Endogenous Cannabinoids

Journal: Current Neuropharmacology
Volume: 2,Issue: 1
Page: 49-57
Authors: M. Kano, T. Ohno-Shosaku, T. Maejima, T. Yoshida and K. Hashimoto

Drugs from the Sea: Conopeptides as Potential Therapeutics

Journal: Current Medicinal Chemistry
Volume: 11,Issue: 13
Page: 1715-1723
Authors: Bruce G. Livett, Ken R. Gayler and Zeinab Khalil

Toward Atomic-Scale Understanding of Ligand Recognition in the Muscle Nicotinic Receptor

Journal: Current Medicinal Chemistry
Volume: 11,Issue: 5
Page: 559-567
Authors: Steven M. Sine, Hai-Long Wang and Fan Gao

The 5-HT3 and nACh Ionotropic Receptors: A Perspective from the Computational Chemistry Point of View

Journal: Current Medicinal Chemistry
Volume: 9,Issue: 1
Page: 99-125
Authors: A. Morreale, I. Iriepa and E. Galvez

Cholinesterase Reactivators: The Fate and Effects in the Organism Poisoned with Organophosphates/Nerve Agents

Journal: Current Drug Metabolism
Volume: 8,Issue: 8
Page: 803-809
Authors: J. Bajgar, K. Kuca, D. Jun, L. Bartosova and J. Fusek

Nitric Oxide Synthase Function in Exercise

Journal: Current Enzyme Inhibition
Volume: 4,Issue: 1
Page: 37-45
Authors: Pasquale Pagliaro, Daniele Mancardi and Claudia Penna

Role of the Central Cholinergic System in the Therapeutics of Schizophrenia

Journal: Current Neuropharmacology
Volume: 6,Issue: 3
Page: 286-292
Authors: Alvin V. Terry and Jr.

Pyridinium Oximes as Cholinesterase Reactivators. Structure-Activity Relationship and Efficacy in the Treatment of Poisoning with Organophosphorus Compounds

Journal: Current Medicinal Chemistry
Volume: 16,Issue: 17
Page: 2177-2188
Authors: Milan Jokanovic and Milica Prostran

HMGB1-Directed Drug Discovery Targeting Cutaneous Inflammatory Dysregulation

Journal: Current Drug Metabolism
Volume: 11,Issue: 3
Page: 250-265
Authors: Sarah D. Lamore, Christopher M. Cabello and Georg T. Wondrak

Treating the Cognitive Deficits of Schizophrenia with Alpha4Beta2 Neuronal Nicotinic Receptor Agonists

Journal: Current Pharmaceutical Design
Volume: 16,Issue: 3
Page: 309-322
Authors: Richard J. Radek, Kathy L. Kohlhaas, Lynne E. Rueter and Eric G. Mohler

Mutations Associated with Anthelmintic Drug Resistance

Journal: Anti-Infective Agents in Medicinal Chemistry
Volume: 9,Issue: 3
Page: 105-112
Authors: R.N. Beech and A. Silvestre

Melatonin, a Potential Therapeutic Agent for Smooth Muscle-Related Pathological Conditions and Aging

Journal: Current Medicinal Chemistry
Volume: 17,Issue: 34
Page: 4150-4165
Authors: M. J. Pozo, P. J. Gomez-Pinilla, C. Camello-Almaraz, F. E. Martin-Cano, P. Pascua, M. A. Rol, D. Acuna-Castroviejo and P. J. Camello

TRP Channels in the Digestive System

Journal: Current Pharmaceutical Biotechnology
Volume: 12,Issue: 1
Page: 24-34
Authors: Peter Holzer

Piribedil: Antiparkinsonian Properties and Potential Clinical Utility in Dopaminergic Disorders

Journal: Current Drug Therapy
Volume: 6,Issue: 1
Page: 17-34
Authors: Aravind Mittur

The Role of the Nervous System in the Regulation of Liver Cytochrome P450

Journal: Current Drug Metabolism
Volume: 12,Issue: 2
Page: 124-138
Authors: Jacek Wojcikowski and Wladyslawa Anna Daniel

Gamma-Amino Butyric Acid Inhibits the Nicotine-Imposed Stimulatory Challenge in Xenograft Models of Non-Small Cell Lung Carcinoma

Journal: Current Cancer Drug Targets
Volume: 12,Issue: 2
Page: 97-106
Authors: H. A.N. Al-Wadei, M. H. Al-Wadei, M. F. Ullah and H. M. Schuller

A Current Review of Cypermethrin-Induced Neurotoxicity and Nigrostriatal Dopaminergic Neurodegeneration

Journal: Current Neuropharmacology
Volume: 10,Issue: 1
Page: 64-71
Authors: Anand Kumar Singh, Manindra Nath Tiwari, Om Prakash and Mahendra Pratap Singh

Ladostigil: A Novel Multimodal Neuroprotective Drug with Cholinesterase and Brain-Selective Monoamine Oxidase Inhibitory Activities for Alzheimers Disease Treatment

Journal: Current Drug Targets
Volume: 13,Issue: 4
Page: 483-494
Authors: Orly Weinreb, Tamar Amit, Orit Bar-Am and Moussa B.H. Youdim

Bivalent Ligands Derived from Huperzine A as Acetylcholinesterase Inhibitors

Journal: Current Topics in Medicinal Chemistry
Volume: 7,Issue: 4
Page: 375-387
Authors: H. Haviv, D. M. Wong, I. Silman and J. L. Sussman

Kynurenines in the Central Nervous System: Recent Developments

Journal: Central Nervous System Agents in Medicinal Chemistry
Volume: 7,Issue: 1
Page: 45-56
Authors: Hajnalka Nemeth, Hermina Robotka, Jozsef Toldi and Laszlo Vecsei

The Effect of Flavonol Glycosides on Opiate Withdrawal

Journal: Medicinal Chemistry
Volume: 3,Issue: 4
Page: 327-331
Authors: Anna Capasso

Analysis of Genetic Polymorphisms in Acetylcholinesterase as Reflected in Different Populations

Journal: Current Alzheimer Research
Volume: 2,Issue: 2
Page: 207-218
Authors: Yehudit Hasin, Nili Avidan, Dani Bercovich, Amos D. Korczyn, Israel Silman, Jacques S. Beckmann and Joel L. Sussman

An Overview of Phenserine Tartrate, A Novel Acetylcholinesterase Inhibitor for the Treatment of Alzheimers Disease

Journal: Current Alzheimer Research
Volume: 2,Issue: 3
Page: 281-290
Authors: Nigel H. Greig, Kumar Sambamurti, Qian-sheng Yu, Arnold Brossi, Gosse B. Bruinsma and Debomoy K. Lahiri

Binding Sites of Amyloid β-Peptide in Cell Plasma Membrane and Implications for Alzheimers Disease

Journal: Current Protein & Peptide Science
Volume: 5,Issue: 1
Page: 19-31
Authors: Yann Verdier and Botond Penke

Vasomotor Effects of Iodinated Contrast Media: Just Side Effects?

Journal: Current Vascular Pharmacology
Volume: 1,Issue: 3
Page: 321-328
Authors: Ugo Limbruno and Raffaele De Caterina

Cerebral Acetylcholinesterase Imaging: Development of the Radioprobes

Journal: Current Topics in Medicinal Chemistry
Volume: 7,Issue: 18
Page: 1790-1799
Authors: Tatsuya Kikuchi, Toshimitsu Okamura, Kiyoshi Fukushi, Kazuhiro Takahashi, Jun Toyohara, Maki Okada, Ming-Rong Zhang and Toshiaki Irie

A Closer Look at α-Secretase

Journal: Current Alzheimer Research
Volume: 5,Issue: 2
Page: 179-186
Authors: Rolf Postina

Molecule of the Month

Journal: Current Topics in Medicinal Chemistry
Volume: 8,Issue: 6
Page: 531-531
Authors: Craig W. Lindsley

Methisergide Selective Inhibition of Opioid Acute Physical Dependence in Isolated Tissues

Journal: Medicinal Chemistry
Volume: 4,Issue: 4
Page: 309-312
Authors: Anna Capasso

Cholinesterase Inhibitors and Beyond

Journal: Current Alzheimer Research
Volume: 6,Issue: 2
Page: 86-96
Authors: Giancarlo Pepeu and Maria Grazia Giovannini

A Closer Look at the High Affinity Benzodiazepine Binding Site on GABAA Receptors

Journal: Current Topics in Medicinal Chemistry
Volume: 11,Issue: 2
Page: 241-246
Authors: Erwin Sigel and Benjamin P. Luscher

Rosiglitazone Does Not Improve Cognition or Global Function when Used as Adjunctive Therapy to AChE Inhibitors in Mild-to-Moderate Alzheimers Disease: Two Phase 3 Studies

Journal: Current Alzheimer Research
Volume: 8,Issue: 5
Page: 592-606
Authors: C. Harrington, S. Sawchak, C. Chiang, J. Davies, C. Donovan, A. M. Saunders, M. Irizarry, B. Jeter, M Zvartau-Hind, C. H. van Dyck and M. Gold

An Overview on Natural Cholinesterase Inhibitors - A Multi-Targeted Drug Class - and Their Mass Production

Journal: Mini-Reviews in Medicinal Chemistry
Volume: 11,Issue: 10
Page: 836-842
Authors: I. Erdogan Orhan, G. Orhan and E. Gurkas

Effects of Cholinergic Enhancing Drugs on Cholinergic Transporters in the Brain and Peripheral Blood Lymphocytes of Spontaneously Hypertensive Rats

Journal: Current Alzheimer Research
Volume: 9,Issue: 1
Page: 120-127
Authors: Daniele Tomassoni, Assia Catalani, Carlo Cinque, Maria Antonietta Di Tullio, Seyed Khosrow Tayebati, Angela Cadoni, Innocent Ejike Nwankwo, Enea Traini and Francesco Amenta

Application of the In Combo Screening Approach For the Discovery of Non-Alkaloid Acetylcholinesterase Inhibitors from Cichorium intybus

Journal: Current Drug Discovery Technologies
Volume: 2,Issue: 3
Page: 185-193
Authors: J. M. Rollinger, P. Mock, C. Zidorn, E. P. Ellmerer, T. Langer and H. Stuppner

The Neuronal Histaminergic System in Cognition

Journal: Current Medicinal Chemistry-Central Nervous System Agents
Volume: 4,Issue: 1
Page: 17-26
Authors: M. B. Passani and P. Blandina

Galanin: A Biologically Active Peptide

Journal: Current Drug Target -CNS & Neurological Disorders
Volume: 1,Issue: 6
Page: 531-541
Authors: Maria E. Vrontakis

Muscarinic Receptors as a Target for Drugs Treating Schizophrenia

Journal: Current Drug Target -CNS & Neurological Disorders
Volume: 1,Issue: 2
Page: 163-181
Authors: Frank P. Bymaster, Christian Felder, Saeed Ahmed and David McKinzie

Nicotinic Receptor Mutant Mice in the Study of Autonomic Function

Journal: Current Drug Target -CNS & Neurological Disorders
Volume: 1,Issue: 4
Page: 331-336
Authors: Mariella De Biasi

Human Brain Nicotinic Receptors, their Distribution and Participation in Neuropsychiatric Disorders

Journal: Current Drug Target -CNS & Neurological Disorders
Volume: 1,Issue: 4
Page: 387-397
Authors: A. J. Graham, C. M. Martin-Ruiz, T. Teaktong, M. A. Ray and J. A. Court

The Role of Neurogenesis in Neurodegenerative Diseases and its Implications for Therapeutic Development

Journal: CNS & Neurological Disorders - Drug Targets
Volume: 7,Issue: 2
Page: 187-210
Authors: Andrea Abdipranoto, Sara Wu, Sandy Stayte and Bryce Vissel

The Genetic Components of Alcohol and Nicotine Co-Addiction: From Genes to Behavior

Journal: Current Drug Abuse Reviews
Volume: 1,Issue: 2
Page: 124-134
Authors: Isabel R. Schlaepfer, Nicole R. Hoft and Marissa A. Ehringer

Modulation of Transmitter Release Via Presynaptic Ligand-Gated Ion Channels

Journal: Current Molecular Pharmacology
Volume: 1,Issue: 2
Page: 106-129
Authors: K. W. Schicker, M. M. Dorostkar and S. Boehm

Regulation of G-Protein-Coupled Receptor Signalling by the Scaffolding Proteins Spinophilin/Neurabin 2 and Neurabin 1

Journal: Current Chemical Biology
Volume: 5,Issue: 2
Page: 130-141
Authors: Denis Sarrouilhe and Thierry Metaye

Human Genetic Variation: A Foundation for Rational Diagnosis and Individualized Treatment of Lung Cancer

Journal: Current Pharmacogenomics and Personalized Medicine
Volume: 7,Issue: 2
Page: 133-145
Authors: O. M. Shaw, N. L. Misso, B. P. Shelton and K. D. Bhoola

Effects of a Long-Term Treatment with an Antioxidant Pyridoindole on Vascular Responsiveness in Diabetes-Induced Aging Rats

Journal: Current Aging Science
Volume: 4,Issue: 2
Page: 150-157
Authors: Asli F. Ceylan-Isik, Nuray Ari, Milan Stefek, Ruzena Sotnikova, Gulgun Ozansoy, Lubica Horakova and Cimen Karasu

Regulatory Role of the α7nAChR in Cancer

Journal: Current Drug Targets
Volume: 13,Issue: 5
Page: 680-687
Authors: Hildegard M. Schuller

Beta-adrenergic Signaling in the Development and Progression of Pulmonary and Pancreatic Adenocarcinoma

Journal: Current Cancer Therapy Reviews
Volume: 8,Issue: 2
Page: 116-127
Authors: Hildegard M. Schuller and Hussein A. N. Al-Wadei

Choline Transporter CHT Regulation and Function in Cholinergic Neurons

Journal: Central Nervous System Agents in Medicinal Chemistry
Volume: 12,Issue: 2
Page: 114-121
Authors: Stefanie A.G. Black and R. Jane Rylett

Tumor Growth is Stimulated by Muscarinic Receptor Agonism: Role of Autoantibodies in Breast Cancer Patients

Journal: Immunology‚ Endocrine & Metabolic Agents in Medicinal Chemistry
Volume: 12,Issue: 3
Page: 208-215
Authors: Maria Elena Sales

Roles of Glycogen Synthase Kinase 3 in Alzheimer’s Disease

Journal: Current Alzheimer Research
Volume: 9,Issue: 7
Page: 864-879
Authors: Zhiyou Cai, Yu Zhao and Bin Zhao

Structure-Activity Relationship and Efficacy of Pyridinium Oximes in the Treatment of Poisoning with Organophosphorus Compounds: A Review of Recent Data

Journal: Current Topics in Medicinal Chemistry
Volume: 12,Issue: 16
Page: 1775-1789
Authors: Milan Jokanovic

Impaired Neurovascular Coupling in the APPxPS1 Mouse Model of Alzheimer’s Disease

Journal: Current Alzheimer Research
Volume: 9,Issue: 10
Page: 1221-1230
Authors: Armelle Rancillac, Helene Geoffroy and Jean Rossier

Role of CHRNA5-A3 Genetic Locus Variants and Developing Drug for Chronic Obstructive Pulmonary Disease

Journal: Current Medicinal Chemistry
Volume: 19,Issue: 34
Page: 5863-5870
Authors: F. Lococo, A. Cesario, L. Petracca-Ciavarella, P. Granone and P. Russo

Novel Insights into the Pervasive Role of M3 Muscarinic Receptor in Cardiac Diseases

Journal: Current Drug Targets
Volume: 14,Issue: 3
Page: 372-377
Authors: Pengzhou Hang, Jing Zhao, Jiancui Qi, Yan Wang, Jianwei Wu and Zhimin Du

Cellular Signaling Crosstalk Between Multiple Receptors for Investigation of Pathophysiology in Multifactorial Diseases - What is Clinically-Relevant Crosstalk?

Journal: Current Medicinal Chemistry
Volume: 20,Issue: 9
Page: 1091-1102
Authors: T. Yoshikawa and H. Kanazawa

Physiological Role of Peroxisome Proliferator-Activated Receptors Type Alpha on Dopamine Systems

Journal: CNS & Neurological Disorders - Drug Targets
Volume: 12,Issue: 1
Page: 70-77
Authors: Miriam Melis, Gianfranca Carta, Marco Pistis and Sebastiano Banni

Neurotransmitters and Microglial-Mediated Neuroinflammation

Journal: Current Protein & Peptide Science
Volume: 14,Issue: 1
Page: 21-32
Authors: Moonhee Lee

Pathogenesis of Abeta Oligomers in Synaptic Failure

Journal: Current Alzheimer Research
Volume: 10,Issue: 3
Page: 316-323
Authors: Senthilkumar Sivanesan, Aaron Tan and Jayakumar Rajadas

Functional Effects of Levosimendan in Rat Basilar Arteries In Vitro

Journal: Current Neurovascular Research
Volume: 10,Issue: 2
Page: 126-133
Authors: Juergen Konczalla, Jan Mrosek, Stefan Wanderer, Patrick Schuss, Erdem Guresir, Volker Seifert, Hartmut Vatter and Johannes Platz

High Fat Diet and Gut Barrier Function

Journal: Current Nutrition & Food Science
Volume: 9,Issue: 2
Page: 108-112
Authors: A.C. van den Heijkant, M.D.P Luyer and W.A. Buurman

Nicotinic Receptors in Neurodegeneration

Journal: Current Neuropharmacology
Volume: 11,Issue: 3
Page: 298-314
Authors: Inmaculada Posadas, Beatriz Lopez-Hernandez and Valentin Cena

Binding Modes and Pharmacophoric Features of Muscarinic Antagonism and β2 Agonism (MABA) Conjugates

Journal: Current Topics in Medicinal Chemistry
Volume: 13,Issue: 14
Page: 1650-1655
Authors: Srinivas Bandaru, M. Hema Prasad, A. Jyothy, Anuraj Nayarisseri and Mukesh Yadav

Inhibition of Cardiac Inward Rectifier Currents by Cationic Amphiphilic Drugs

Journal: Current Molecular Medicine
Volume: 13,Issue: 8
Page: 1284-1298
Authors: M. A.G. van der Heyden, A. Stary-Weinzinger and J. A. Sanchez-Chapula

Natural Products as Sources of New Lead Compounds for the Treatment of Alzheimer’s Disease

Journal: Current Topics in Medicinal Chemistry
Volume: 13,Issue: 15
Page: 1864-1878
Authors: Ling Huang, Tao Su and Xingshu Li

Disorders of Consciousness and Pharmaceuticals that Act on Oxygen Based Amino Acid and Monoamine Neurotransmitter Pathways of the Brain

Journal: Current Pharmaceutical Design
Volume: 20,Issue: 26
Page: 4140-4153
Authors: Ralf Clauss

Selective Acetyl- and Butyrylcholinesterase Inhibitors Reduce Amyloid-β Ex Vivo Activation of Peripheral Chemo-cytokines From Alzheimer's Disease Subjects: Exploring the Cholinergic Anti-inflammatory Pathway

Journal: Current Alzheimer Research
Volume: 11,Issue: 6
Page: 608-622
Authors: Marcella Reale, Marta Di Nicola, Lucia Velluto, Chiara D’Angelo, Erica Costantini, Debomoy K. Lahiri, Mohammad A. Kamal, Qian-sheng Yu and Nigel H. Greig

Assessing and Treating Cognitive Impairment in Schizophrenia: Current and Future

Journal: Current Pharmaceutical Design
Volume: 20,Issue: 32
Page: 5127-5138
Authors: Chun-Yuan Lin, Guochuan E. Tsai and Hsien-Yuan Lane

Structural and Pathogenic Mechanisms Centered on Muscle-Specific Tyrosine Kinase in Autoimmune Neuromuscular Junction Disorders

Journal: Current Immunology Reviews
Volume: 9,Issue: 4
Page: 207-213
Authors: Masaharu Takamori

Quinoxaline Derivatives: Novel and Selective Butyrylcholinesterase Inhibitors

Journal: Medicinal Chemistry
Volume: 10,Issue: 7
Page: 724-729
Authors: Aurang Zeb, Abdul Hameed, Latifullah Khan, Imran Khan, Kourosh Dalvandi, M. Iqbal Choudhary and Fatima Z. Basha

Alpha7 Neuronal Nicotinic Receptor: A Pluripotent Target for Diseases of the Central Nervous System

Journal: CNS & Neurological Disorders - Drug Targets
Volume: 13,Issue: 5
Page: 836-845
Authors: Merouane Bencherif, Sridhar T. Narla and Michal S. Stachowiak

Newly Synthesized Acetylcholinesterase Inhibitors for Alleviating Alzheimer’s Disease using Solid Lipid Nanoparticles

Journal: Current Drug Therapy
Volume: 9,Issue: 2
Page: 111-123
Authors: Rohit Makkar, Paramveer Singh, Chhanda C. Danta, Vandita Kakkar, Indu P. Kaur and Poonam Piplani

Inhibitory Effect of Ebselen on Cerebral Acetylcholinesterase Activity In Vitro: Kinetics and Reversibility of Inhibition

Journal: Current Pharmaceutical Design
Volume: 21,Issue: 7
Page: 920-924
Authors: Franciele Martini, César Augusto Bruning, Suelen Mendonca Soares, Cristina Wayne Nogueira and Gilson Zeni

Cholinergic Receptors as Target for Cancer Therapy in a Systems Medicine Perspective

Journal: Current Molecular Medicine
Volume: 14,Issue: 9
Page: 1126-1138
Authors: P. Russo, A. Del Bufalo, M. Milic, G. Salinaro, M. Fini and A. Cesario

Age-Related Changes and Effects of Mild Hypothermia on Carotid Artery Reactivity in Newborn Rats

Journal: CNS & Neurological Disorders - Drug Targets
Volume: 14,Issue: 1
Page: 91-101
Authors: Giacomo Cavallaro, Else Bijker, Eveline Strackx, Johan S.H. Vles, Danilo Gavilanes and Eduardo Villamor

Design and Development of a Novel Supportive Care Product for the Treatment of Sialorrhea in Parkinson’s Disease

Journal: Current Topics in Medicinal Chemistry
Volume: 15,Issue: 10
Page: 939-954
Authors: Neal M. Farber, Santiago Perez-Lloret and Elkan R. Gamzu

Antioxidant and Acetylcholinesterase Inhibitory Potential of Thai Medicinal Plants

Journal: Current Nutrition & Food Science
Volume: 11,Issue: 2
Page: 99-104
Authors: Boonsong Kasempitakpong, Winthana Kusirisin, Churdsak Jaikang and Nipon Sermpanich

5-HT6 Receptor Antagonists: Potential Efficacy for the Treatment of Cognitive Impairment in Schizophrenia

Journal: Current Pharmaceutical Design
Volume: 21,Issue: 26
Page: 3739-3759
Authors: Natasja M.W.J. de Bruin and Chris G Kruse

L-Arginine Transport and Nitric Oxide Production in Kinin Receptor B1-/- Endothelial Cells.

Journal: Protein & Peptide Letters
Volume: 22,Issue: 12
Page: 1111-1116
Authors: Renato C. Tudela, Rodrigo A. Loiola, Tathiany C. Torres, Noemi L. Gil, Nilson A. Assunção, Samuel M.R. de Noronha, Silvana A. Correa-Noronha, Richardt G. Landgraf and Liliam Fernandes

The Many Neuroprogressive Actions of Tryptophan Catabolites (TRYCATs) that may be Associated with the Pathophysiology of Neuro-Immune Disorders

Journal: Current Pharmaceutical Design
Volume: 22,Issue: 8
Page: 963-977
Authors: Gerwyn Morris, André F. Carvalho, George Anderson, Piotr Galecki and Michael Maes

Promising Therapies for Alzheimer's Disease

Journal: Current Pharmaceutical Design
Volume: 22,Issue: 14
Page: 2050-2056
Authors: Annamaria Confaloni, Giuseppe Tosto and Ada Maria Tata

Muscarinic Receptors as Targets for Metronomic Therapy in Breast Cancer

Journal: Current Pharmaceutical Design
Volume: 22,Issue: 14
Page: 2170-2177
Authors: María Elena Sales

In Silico Analysis of Green Tea Polyphenols as Inhibitors of AChE and BChE Enzymes in Alzheimer’s Disease Treatment

Journal: CNS & Neurological Disorders - Drug Targets
Volume: 15,Issue: 5
Page: 624-628
Authors: Babar Ali, Qazi M.S. Jamal, Saiba Shams, Naser A. Al-Wabel, Mughees U. Siddiqui, Mohammad A. Alzohairy, Mohammed A. Al Karaawi, Kavindra Kumar Kesari, Gohar Mushtaq and Mohammad A. Kamal

Polypharmacological Properties and Therapeutic Potential of β-Caryophyllene: A Dietary Phytocannabinoid of Pharmaceutical Promise

Journal: Current Pharmaceutical Design
Volume: 22,Issue: 21
Page: 3237-3264
Authors: Charu Sharma, Juma M. Al Kaabi, Syed M. Nurulain, Sameer N. Goyal, Mohammad Amjad Kamal and Shreesh Ojha

Heterocyclic Scaffolds for the Treatment of Alzheimer’s Disease

Journal: Current Pharmaceutical Design
Volume: 22,Issue: 26
Page: 3971-3995
Authors: Annamaria Martorana, Valentina Giacalone, Riccardo Bonsignore, Andrea Pace, Carla Gentile, Ivana Pibiri, Silvestre Buscemi, Antonino Lauria and Antonio Palumbo Piccionello

Butyrylcholinesterase as a Diagnostic and Therapeutic Target for Alzheimer’s Disease

Journal: Current Alzheimer Research
Volume: 13,Issue: 10
Page: 1173-1177
Authors: Sultan Darvesh

Nitric Oxide: A Universal Modulator of Brain Function

Journal: Current Medicinal Chemistry
Volume: 23,Issue: 24
Page: 2643-2652
Authors: Athineos Philippu

Soluble Neuregulin-1 from Microglia Enhances Amyloid Beta-induced Neuronal Death

Journal: CNS & Neurological Disorders - Drug Targets
Volume: 15,Issue: 8
Page: 918-926
Authors: Hyunjeong Liew, Yun-Mi Kim, Hee Soon Choi, Ah Ram Jang, David Churchill, Sang Hyung Lee and Yoo-Hun Suh

Substance P Prevents Vascular Endothelial Dysfunction in Metastatic Breast Carcinoma

Journal: Protein & Peptide Letters
Volume: 23,Issue: 11
Page: 952-957
Authors: Selvinaz Dalaklioglu and Nuray Erin

Multiple Faceted Roles of Cocaine in Potentiation of HAND

Journal: Current HIV Research
Volume: 14,Issue: 5
Page: 412-416
Authors: Yu Cai, Lu Yang, Shannon Callen and Shilpa Buch

Classical Neurotransmitters and Neuropeptides Involved in Parkinson's Disease: Focus on Anti-Parkinsonian Drugs

Journal: Current Drug Therapy
Volume: 10,Issue: 2
Page: 66-81
Authors: Felix-Martin Werner and Rafael Coveñas

Remodelling of the Ca2+ Toolkit in Tumor Endothelium as a Crucial Responsible for the Resistance to Anticancer Therapies

Journal: Current Signal Transduction Therapy
Volume: 12,Issue: 1
Page: 3-18
Authors: Francesco Moccia*

Piroxicam: Source for Synthesis of Central Nervous System (CNS) Acting Drugs

Journal: Central Nervous System Agents in Medicinal Chemistry
Volume: 17,Issue: 2
Page: 135-140
Authors: Saganuwan Alhaji Saganuwan*

Cholinergic System and Neuroinflammation: Implication in Multiple Sclerosis

Journal: Central Nervous System Agents in Medicinal Chemistry
Volume: 17,Issue: 2
Page: 109-115
Authors: Maria Di Bari, Giovanni Di Pinto, Marcella Reale, Guadalupe Mengod* and Ada Maria Tata*

Neuromodulation of Spinal Locomotor Networks in Rodents

Journal: Current Pharmaceutical Design
Volume: 23,Issue: 12
Page: 1741-1752
Authors: Manuel Diaz-Ríos*, Pierre A. Guertin and Marla Rivera-Oliver

Translational Multimodality Neuroimaging

Journal: Current Drug Targets
Volume: 18,Issue: 9
Page: 1039-1050
Authors: Sushil Sharma*

Molecular and Cellular Mechanisms of Rapid-Acting Antidepressants Ketamine and Scopolamine

Journal: Current Neuropharmacology
Volume: 15,Issue: 1
Page: 11-20
Authors: Eric S. Wohleb, Danielle Gerhard, Alex Thomas and Ronald S. Duman

A Review: Natural Compounds as Anti-Alzheimer´s Disease Agents

Journal: Current Nutrition & Food Science
Volume: 13,Issue: 4
Page: 247-254
Authors: Asha Hiremathad*

Alzheimer’s Disease-like Early-phase Brain Pathogenesis: Self-curing Amelioration of Neurodegeneration from Pro-inflammatory ‘Wounding’ to Anti-inflammatory ‘Healing’

Journal: Current Alzheimer Research
Volume: 14,Issue: 10
Page: 1123-1135
Authors: Jiang He, Tao Liao, Guo-Xin Zhong, Ji-Da Zhang, Yan-Ping Chen, Qi Wang* and Qing-Ping Zeng*

Inhibition of Butyrylcholinesterase with Fluorobenzylcymserine, An Experimental Alzheimer's Drug Candidate: Validation of Enzoinformatics Results by Classical and Innovative Enzyme Kinetic Analyses

Journal: CNS & Neurological Disorders - Drug Targets
Volume: 16,Issue: 7
Page: 820-827
Authors: Mohammad A. Kamal*, Shazi Shakil, Muhammad S. Nawaz, Qian-sheng Yu, David Tweedie, Y. Tan, Xianqin Qu and Nigel H. Greig*

Trends in the Development of New Antidepressants. Is there a Light at the End of the Tunnel?

Journal: Current Medicinal Chemistry
Volume: 11,Issue: 7
Page: 925-943
Authors: Pal Pacher and Valeria Kecskemeti

Synaptic Potentiation and Sleep Need: Clues from Molecular and Electrophysiological Studies

Journal: Current Topics in Medicinal Chemistry
Volume: 11,Issue: 19
Page: 2472-2482
Authors: Erin C. Hanlon, Vladyslav V. Vyazovskiy, Ugo Faraguna, Giulio Tononi and Chiara Cirelli

BACE1 Dependent Neuregulin Processing: Review

Journal: Current Alzheimer Research
Volume: 9,Issue: 2
Page: 178-183
Authors: Daniel Fleck, Alistair N. Garratt, Christian Haass and Michael Willem

Molecular Interaction Study of N1-p-fluorobenzyl-cymserine with TNF-α , p38 Kinase and JNK Kinase

Journal: Anti-Inflammatory & Anti-Allergy Agents in Medicinal Chemistry
Volume: 12,Issue: 2
Page: 129-135
Authors: Sidra Batool, Muhammad Sulaman Nawaz, Nigel H. Greig, Mohd Rehan and Mohammad A. Kamal

New Pharmacological Approaches to the Cholinergic System: An Overview on Muscarinic Receptor Ligands and Cholinesterase Inhibitors

Journal: Recent Patents on CNS Drug Discovery
Volume: 8,Issue: 2
Page: 123-141
Authors: Nigel H. Greig, Marcella Reale and Ada M. Tata

Inquiries into the Biological Significance of Transmembrane AMPA Receptor Regulatory Protein (TARP) γ−8 Through Investigations of TARP γ−8 Null Mice§

Journal: CNS & Neurological Disorders - Drug Targets
Volume: 14,Issue: 5
Page: 612-626
Authors: Scott D. Gleason, Akihiko Kato, Hai H. Bui, Linda K. Thompson, Sabrina N. Valli, Patrick V. Stutz, Ming-Shang Kuo, Julie F. Falcone, Wesley H. Anderson, Xia Li and Jeffrey M. Witkin

Serotonergic Drugs: Agonists/Antagonists at Specific Serotonergic Subreceptors for the Treatment of Cognitive, Depressant and Psychotic Symptoms in Alzheimer’s Disease

Journal: Current Pharmaceutical Design
Volume: 22,Issue: 14
Page: 2064-2071
Authors: Felix-Martin Werner and Rafael Covenas

Lecithin (Phosphatidylcholine): Healthy Dietary Supplement or Dangerous Toxin?

Journal: The Natural Products Journal
Volume: 6,Issue: 4
Page: 242-249
Authors: Robert E. Smith, Philip Rouchotas and Heidi Fritz

Effect of Genetic Polymorphisms (SNPs) in CHRNA7 Gene on Response to Acetylcholinesterase Inhibitors (AChEI) in Patients with Alzheimer’s Disease

Journal: Current Drug Targets
Volume: 18,Issue: 10
Page: 1179-1190
Authors: Patrizia Russo*, Aliaksei Kisialiou, Rossana Moroni, Giulia Prinzi and Massimo Fini

Theoretical Possibilities for the Development of Novel Antiarrhythmic Drugs

Journal: Current Medicinal Chemistry
Volume: 11,Issue: 1
Page: 1-11
Authors: Andras Varro, Peter Biliczki, Norbert Iost, Laszlo Virag, Otto Hala, Peter Kovacs, Peter Matyus and Julius Gy. Papp

Neuronal Nicotinic Receptors and Neuroprotection: Newer Ligands May Help us Understand their Role in Neurodegeneration

Journal: Medicinal Chemistry Reviews - Online (Discontinued)
Volume: 2,Issue: 6
Page: 455-471
Authors: M. J. O'Neill, P. Astles, C. P. Dell, M. Keenan, T. K. Murray, V. Lakics, N. P. Visanji and S. Duty

Organophosphorus Inhibition and Characterization of Recombinant Guinea Pig Acetylcholinesterase

Journal: Protein & Peptide Letters
Volume: 22,Issue: 10
Page: 862-868
Authors: Christopher D. Ruark, Richard R. Chapleau, Deirdre A. Mahle and Jeffery M. Gearhart

Molecule of the Month

Journal: Current Topics in Medicinal Chemistry
Volume: 7,Issue: 13
Page: 1330-1330
Authors: Micah L. Breininger and Craig W. Lindsley

β-Amyloid, Cholinergic Transmission, and Cerebrovascular System - A Developmental Study in a Mouse Model of Alzheimer's Disease

Journal: Current Pharmaceutical Design
Volume: 19,Issue: 38
Page: 6749-6765
Authors: Elena Kuznetsova and Reinhard Schliebs

Editorial (Thematic Issue: Disease Control and Active and Healthy Ageing: New Paradigms of Therapeutic Strategy)

Journal: Current Pharmaceutical Design
Volume: 20,Issue: 38
Page: 5919-5920
Authors: Patrizia Russo, Massimo Fini and Alfredo Cesario

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