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Current Pharmaceutical Design


ISSN (Print): 1381-6128
ISSN (Online): 1873-4286

Review Article

Use of Natural Components Derived from Oil Seed Plants for Treatment of Inflammatory Skin Diseases

Author(s): Monika Styrczewska, Magdalena Zuk, Aleksandra Boba, Iwan Zalewski and Anna Kulma*

Volume 25 , Issue 20 , 2019

Page: [2241 - 2263] Pages: 23

DOI: 10.2174/1381612825666190716111700

Price: $65


The incidence of inflammatory skin diseases is increasing, so the search for relevant therapeutics is of major concern. Plants are rich in phytochemicals which can alleviate many symptoms. In this review, we concentrate on compounds found in the seeds of widely cultivated plants, regularly used for oil production. The oils from these plants are often used to alleviate the symptoms of inflammatory diseases through synergetic action of unsaturated fatty acids and other phytochemicals most commonly derived from the terpenoid pathway. The knowledge of the chemical composition of oil seeds and the understanding of the mechanisms of action of single components should allow for a more tailored approach for the treatment for many diseases. In many cases, these seeds could serve as an efficient material for the isolation of pure phytochemicals. Here we present the content of phytochemicals, assumed to be responsible for healing properties of plant oils in a widely cultivated oil seed plants and review the proposed mechanism of action for fatty acids, selected mono-, sesqui-, di- and triterpenes, carotenoids, tocopherol and polyphenols.

Keywords: Inflammatory skin diseases, oil, terpenoids, carotenoids, fatty acid, phenylpropanoids.

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