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Current Pharmaceutical Design

Editor-in-Chief

ISSN (Print): 1381-6128
ISSN (Online): 1873-4286

Review Article

Opioid Free Anaesthesia and Cancer

Author(s): Alfredo Malo-Manso*, Aida Raigon-Ponferrada*, Julia Diaz-Crespo, Juan J. Escalona-Belmonte, Jose Cruz-Mañas and Jose L. Guerrero-Orriach

Volume 25 , Issue 28 , 2019

Page: [3011 - 3019] Pages: 9

DOI: 10.2174/1381612825666190705183754

Price: $65

Abstract

Opioid-free anesthesia is revolutionizing anesthetic practices for its potential benefits in selected patients. Opioid-free anesthesia represents a step forward in anesthetic practice as it has been suggested to provide potential clinical benefits for selected patients. Opioid-free anesthesia spares the use of opioids and involves the administration of multiple adjuvant anesthetics, which may have an impact on cancer progression. All this have added to the growing interest in the immune response to anesthetics, making opioid-free anesthesia a promising avenue for future research.

Assessing the role of anesthetics in immunomodulation in the surgical setting is challenging, and results are often contradictory. Indeed, there is a scarcity of data of studies on humans, which hinder the interpretation of results. However, promising evidence has been published that cancer progression can be delayed by the administration of specific anesthetic agents.

Keywords: Opioid free anaesthesia, cancer, opioids, anaesthesia, metastases, recurrence, oncology, surgery.

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