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Current Traditional Medicine


ISSN (Print): 2215-0838
ISSN (Online): 2215-0846

Review Article

Herbal Dentifrices: Emerging Trends and Patterns

Author(s): Rashmi Saxena Pal*, Yogendra Pal, Ankita Wal and Pranay Wal

Volume 6, Issue 1, 2020

Page: [54 - 64] Pages: 11

DOI: 10.2174/2215083805666190626145755

Price: $65


Background: Herbal extracts have been employed since ages in dentistry as tooth cleansing and antimicrobial agents. The use of herbal medicines continues to expand and trend rapidly across the world. Herbal extracts have been used in dentistry for multiple uses as reducing inflammation, as antimicrobial plaque agents, for preventing release of histamine and as antiseptics, antioxidants, antimicrobials and analgesics. They also aid in healing process and are very effective in controlling microbial plaque and other disorders related to gums.

Objective: The present review aims towards the combined review as well as compilation of available herbs under the category of various dental associated problems.

Materials and Methods: The herbs were studied by sectioning them as for looking after different works or findings done against dental caries, tooth ache, scouring teeth, gum troubles and herbs as mouth fresheners.

Results: Herbal extracts have been used on a large scale in dentistry as tooth cleansing and antimicrobial plaque agents. Many people take herbal derived medicines or herbal based products for the purpose of reducing inflammation, as antimicrobial agents, for preventing release of histamine and as antiseptics, antioxidants, antifungals, antibacterials, antivirals and analgesics. Herbal extracts are used in dentistry for treatment of various dental disorders.

Conclusion: The use of herbal medicines are blooming rapidly across the world. Herbal extracts and the various herbs on the whole or their specific parts have been used in dentistry. They relieve the problems of gums and act as excellent mouth fresheners. The natural herbal remedies act as an effective substitute to antibiotics and represent a promising approach for prevention and as therapeutic strategies for various oral infections as they are natural, eradicate the problem from its root and provide long lasting relief. The herbal remedies are advantageous over conventional treatment.

Keywords: Herbal, dentifrices, antimicrobial, caries, toothache, medicinal plants.

Graphical Abstract
Singh LW. Traditional medicinal plants of Manipur as anti-diabetics. J Med Plants Res 2011; 5(5): 677-87.
Scartezzini P, Speroni E. Review on some plants of Indian traditional medicine with antioxidant activity. J Ethnopharmacol 2000; 71(1-2): 23-43.
[] [PMID: 10904144]
Jensen JL, Barkvoll P. Clinical implications of the dry mouth. Oral mucosal diseases. Ann N Y Acad Sci 1998; 842(1): 156-62.
[] [PMID: 9599305]
Scherer W, Gultz J, Lee SS, Kaim J. The ability of an herbal mouth rinse to reduce gingival bleeding. J Clin Dent 1998; 9(4): 97-100.
[PMID: 10518858]
Sharma PP. Cosmetics: Formulation, Manufacture, Quality Control. Ed 5TH. Vandana Publications 2014; pp. 507-19.
Lee SS, Zhang W, Li Y. The antimicrobial potential of 14 natural herbal dentifrices: Results of an in vitro diffusion method study. J Am Dent Assoc 2004; 135(8): 1133-41.
[] [PMID: 15387052]
Arangannal P, Mahadev SK, Jayaprakash J. Prevalence of dental caries among school children in chennai, based on ICDAS II. J Clin Diagn Res 2016; 10(4): ZC09-12.
[] [PMID: 27190939]
Kakoei S, Parirokh M, Nakhaee N, Jamshidshirazi F, Rad M, Kakooei S. Prevalence of toothache and associated factors: A population-based study in southeast iran. Iran Endod J 2013; 8(3): 123-8.
[PMID: 23922574]
[9] How Acidic Foods Affect Teeth and Which to Avoid. by Diana Tosuni..
WebMD. Gingivitis and Periodontal Disease (Gum Disease).
Karagoz G, Bektas-Kayhan K, Unur M. Desquamative gingivitis: A review. J Istanb Univ Fac Dent 2016; 50(2): 54-60.
[] [PMID: 28955567]
[12] Dental Caries (Cavities) available from.
Prabhat A, Navneet CA. Evaluation of antimicrobial activity of six medicinal plants against dental pathogens. Rep Opinion 2010; 2(1): 37-42.
Srivastav S, Singh P, Mishra G, Jha KK, Khosa RL. Achyranthes aspera - An important medicinal plant: A review. J Nat Prod Plant Resour 2011; 1(1): 1-14.
Shukla A, Bukhariya V, Bajaj J, Charde R. Achyranthes aspera linn. (chirchira): A magic herb in folk medicine. Int J Biol Adv Res 2011; 2(6): 372-6.
Tullanithi KM, Sharmila B, Gnanendra TS. Preliminary phytochemical analysis and antimicrobial activity of Achyranthes aspera Linn. Int Biol Technol 2010; 1(1): 35-8.
Iqbal Z, Lateef M, Jabbar A, Muhammad G, Khan MN. Anthelmintic activity of Calotropis procera (Ait.) Ait. F. flowers in sheep. J Ethnopharmacol 2005; 102(2): 256-61.
[] [PMID: 16085379]
Openshaw K. A review of Jatropha curcas: An oil plant of unfulfilled promise. Biomass Bioenergy 2000; 19(1): 1-15.
Gulcan O, Ali KM. Physical and chemical composition of some walnut (Juglans regia L) genotypes grown in Turkey. Grasas Aceites 2005; 56(2): 141-6.
Openshaw K. A review of Jatropha curcas: an oil plant of unfulfilled promise. Biomass and Bioenergy 2000; 19(1): 1-15.
Gulcan O and, Ali KM. Physical and chemical composition of some walnut (Juglans regia L) genotypes grown in Turkey. Grasas y Aceites 2005; 56(2): 141-6.
Irani M, Sarmadi M, Bernard F, Ebrahimi Pour GH, Shaker Bazarnov H. Leaves Antimicrobial Activity of Glycyrrhiza glabra L. Iran J Pharm Res 2010; 9(4): 425-8.
Ajagannanavar SL, et al. Effect of aqueous and alcoholic licorice (glycyrrhiza glabra) root extract against Streptococcus mutans and lactobacillus acidophilus in comparison to chlorhexidine: An in vitro study. J Int Oral Health 2014; 6(4): 29-34.
Smith BH, Elliott AM, Chambers WA, Smith WC, Hannaford PC, Penny K. The impact of chronic pain in the community. Fam Pract 2001; 18(3): 292-9.
[] [PMID: 11356737]
Gherunpong S, Tsakos G, Sheiham A. The prevalence and severity of oral impacts on daily performances in Thai primary school children. Health Qual Life Outcomes 2004; 2(1): 57.
[] [PMID: 15476561]
Luo Y, McMillan AS, Wong MC, Zheng J, Lam CL. Orofacial pain conditions and impact on quality of life in community-dwelling elderly people in Hong Kong. J Orofac Pain 2007; 21(1): 63-71.
[PMID: 17312643]
Nine Herbal Remedies for a Toothache. By Herbal academy. 9 Feb
Shan B, Cai YZ, Sun M, Corke H. Antioxidant capacity of 26 spice extracts and characterization of their phenolic constituents. J Agric Food Chem 2005; 53(20): 7749-59. [PubMed][Google Scholar].
[] [PMID: 16190627]
Kamatou GP, Vermaak I, Viljoen AM. Eugenol- from the remote Maluku Islands to the international market place: A review of a remarkable and versatile molecule. Molecules 2012; 17(6): 6953-81.
[] [PMID: 22728369]
Oliveira RA, Reis TV, Sacramento CK, Duarte LP, Oliveira FF. Volatile chemical constituents of rich spices in eugenol. Rev Bras Farmacogn 2009; 19(3): 771-5.
Tyler VE, Brady LR, Robbers JE. Pharmacognosy Lea & Febriger. Philadelphia, PA: Links 1988.
Zheng GQ, Kenney PM, Lam LKT. Sesquiterpenes from clove (Eugenia caryophyllata) as potential anticarcinogenic agents. J Nat Prod 1992; 55(7): 999-1003.
[] [PMID: 1402962]
Ramirez-Boscα A, Soler A, Gutierrez MA. Antioxidant curcuma extracts decrease the blood lipid peroxide levels of human subjects. 1995; 18(1): 167-9.
Ammon HP, Safayhi H, Mack T, Sabieraj J. Mechanism of antiinflammatory actions of curcumine and boswellic acids. J Ethnopharmacol 1993; 38(2-3): 113-9.
[] [PMID: 8510458]
Derry S, Lloyd R, Moore RA, McQuay HJ. Topical capsaicin for chronic neuropathic pain in adults. Cochrane Database Syst Rev 2009; 7(4) CD007393
[] [PMID: 19821411]
Hempenstall K, Nurmikko TJ, Johnson RW, A’Hern RP, Rice AS. Analgesic therapy in postherpetic neuralgia: A quantitative systematic review. PLoS Med 2005; 2(7) e164
[] [PMID: 16013891]
Altman R, Barkin RL. Topical therapy for osteoarthritis: Clinical and pharmacologic perspectives. Postgrad Med 2009; 121(2): 139-47.
[] [PMID: 19332972]
Bosland PW. Capsicums: Innovative uses of an ancient crop Progress in new crops. Arlington, VA: ASHS Press 1996; pp. 479-87.
Jaiswal R, Ahirwar D. A literature review on Ficus bengalensis. Int J Adv Pharm Res 2013; 5(1): 57-61.
Garg VK, Paliwal SK. Analgesic and anti-pyretic activity of ethanolic and aqueous extracts of Ficus benghalensis. Int J Pharm Pharm Sci 2014; 6(3): 231-4.
Dharmasiri MG, Jayakody JR, Galhena G, Liyanage SSP, Ratnasooriya WD. Anti-inflammatory and analgesic activities of mature fresh leaves of Vitex negundo. J Ethnopharmacol 2003; 87(2-3): 199-206.
[] [PMID: 12860308]
Li RW, Myers SP, Leach DN, Lin GD, Leach G. A cross-cultural study: Anti-inflammatory activity of Australian and Chinese plants. J Ethnopharmacol 2003; 85(1): 25-32.
[] [PMID: 12576199]
Imanshahidi M, Hosseinzadeh H. Pharmacological and therapeutic effects of Berberis vulgaris and its active constituent, berberine. Phytother Res 2008; 22(8): 999-1012.
[] [PMID: 18618524]
Makarem A, Khalili N, Asodeh R. Efficacy of barberry aqueous extracts dental gel on control of plaque and gingivitis. Acta Med Iran 2007; 45(2): 91-4.
Javadzadeh SM, Fallah SR. Therapeutic application_of different parts Berberis vulgaris. Int J Agric Crop Sci 2012; 4(7): 404-8.
Mir SR, Ali M, Kapoor R. Chemical composition of essential oil of Cinnamomum tamala Nees et Eberm. Leaves. J Flavour Fragrance 2000; 19(2): 112-4.
Kiss AS, Markus MT, Sass M. Chemical composition of citrus fruits (orange, lemon, and grapefruit) with respect to quality control of juice products. Nutraceutical Beverages 2009; 3(1): 24-34.
Rio JAD, Fuster MD, Gomez P, Porras I, Lidon AG, Ortuno A. Citrus Limon: A source of flavonoids of pharmaceutical interest. Food Chem 2004; 84(3): 457-61.
Begum S, Hassan SI, Ali SN, Siddiqui BS. Chemical constituents from the leaves of Psidium guajava. Nat Prod Res 2004; 18(2): 135-40.
[] [PMID: 14984086]
Gutiérrez RM, Mitchell S, Solis RV. Psidium guajava: A review of its traditional uses, phytochemistry and pharmacology. J Ethnopharmacol 2008; 117(1): 1-27.
[] [PMID: 18353572]
Health.15 Amazing Guava Benefits: Heart Healthy, Weight Loss Friendly and More Aashna Ahuja July 06 2018.
Rao CV, Vijayakumar M, Sairam K, Kumar V. Antidiarrhoeal activity of the standardised extract of Cinnamomum tamala in experimental rats. J Nat Med 2008; 62(4): 396-402.
[] [PMID: 18493839]
The Fairfield Post. Spices That Are Good For Your Teeth. Posted by Fairfield Dental Associates. Jan 19, 2015. Posted by Fairfield Dental Associates.
Taheri JB, Azimi S, Rafieian N, Zanjani HA. Herbs in dentistry. Int Dent J 2011; 61(6): 287-96.
[] [PMID: 22117784]
Oswal R, Charantimath S. Herbal therapy in dentistry: A review. Innov J Med Health Sci 2011; 1(1): 1-4.
WHO Monographs on Selected Medicinal Plants. Volume 3. Available from:.
Guidelines on Developing Consumer Information on Proper Use of Traditional, Complementary and Alternative Medicine. Available from:
Kukreja BJ, Dodwad V. Herbal mouthwashes: A gift of nature. Int J Pharma Bio Sci 2012; 3(2): 46-52.
Kumar G, Jalaluddin M, Rout P, Mohanty R, Dileep CL. Emerging trends of herbal care in dentistry. J Clin Diagn Res 2013; 7(8): 1827-9.
Corwin A. Herbal supplements: Healthcare implications and considerations. Can Dent Hyg Assoc 2009; 24(4): 7-15.
Kamat S, Rajeev K, Saraf P. Role of herbs in endodontics: An update. Endodontology 2011; 23(1): 98-102.
Wolfram S. Effects of green tea and EGCG on cardiovascular and metabolic health. J Am Coll Nutr 2007; 26(4): 373S-88S.
[] [PMID: 17906191]
Ayub F, Thomas B, Paulaian B, Emil J. Herbs and dental caries - A review. Univ J Pharm 2013; 2(1): 18-21.
Sajjad A, Sajjad SS. Aloe vera: An ancient herb for modern dentistry - A literature review. J Dental Surgery 2014; 2014(1): 6.
Sharma V, Joshi BD. Bio-diversity of medicinal plants in some selected areas of Almora district. J Environ Biosci 2008; 22(1): 39-42.
Huet R. Constituents of Citrus fruits with pharmacodynamics effect: Citroflavonoids. Fruits 1982; 37(1): 267-71.
Kaul TN, Middleton E Jr, Ogra PL. Antiviral effect of flavonoids on human viruses. J Med Virol 1985; 15(1): 71-9.
[] [PMID: 2981979]
Céliz G, Daz M, Audisio MC. Antibacterial activity of naringin derivatives against pathogenic strains. J Appl Microbiol 2011; 111(3): 731-8.
[] [PMID: 21672094]
Mandalari G, Bennett RN, Bisignano G, et al. Antimicrobial activity of flavonoids extracted from bergamot (Citrus bergamia Risso) peel, a byproduct of the essential oil industry. J Appl Microbiol 2007; 103(6): 2056-64.
[] [PMID: 18045389]
Yi LT, Li JM, Li YC, Pan Y, Xu Q, Kong LD. Antidepressant-like behavioral and neurochemical effects of the citrus-associated chemical apigenin. Life Sci 2008; 82(13-14): 741-51.
[] [PMID: 18308340]
Khodayari H, Amani SH, Amiri H. Ethnobotanical medicinal herbs North East Province. Ecophytochem J Med Plants 2014; 8(2): 12-26.
Khajoei NF, Khosravi AR. Ethnobotanical study of medicinal plants of Sirjan in Kerman Province, Iran. J Ethnopharmacol 2014; 154(1): 190-7.
[] [PMID: 24746480]
Iran MM, Najafi SH, Yousefi M. Study of Ethno Botany Medicinal Plants of Sistan. J Herbal Drugs 2010; 2(1): 61-8.
Dolatkhhi M, Nabipour I. Ethnobotanical study of medicinal of plants of northeast of Persian Gulf. J Med Plants 2014; 13(50): 129-43.
George D, Bhat SS, Antony B. Comparative evaluation of the antimicrobial efficacy of aloevera tooth gel and two popular commercial toothpastes: An in vitro study. Gen Dent 2009; 57(3): 238-41.
[PMID: 19819812]
Almas K. The antimicrobial effects of seven different types of Asian chewing sticks. Odontostomatol Trop 2001; 24(96): 17-20.
[PMID: 11887585]
Pepla E, Besharat LK, Palaia G, Tenore G, Migliau G. Nano-hydroxyapatite and its applications in preventive, restorative and regenerative dentistry: A review of literature. Ann Stomatol (Roma) 2014; 5(3): 108-14.
[] [PMID: 25506416]
Schemehorn BR, DiMarino JC, Movahed N. Comparison of the incipient lesion enamel fluoride uptake from various prescription and OTC fluoride toothpastes and gels. J Clin Dent 2014; 25(3): 57-60.
[PMID: 26054179]
Schemehorn BR, DiMarino JC, Movahed N. Comparison of the enamel solubility reduction from various prescription and OTC fluoride toothpastes and gels. J Clin Dent 2014; 25(3): 61-4.
[PMID: 26054180]
Burwell A, Jennings D, Muscle D, Greenspan DC. NovaMin and dentine hypersensitivity- in vitro evidence of efficacy. J Clin Dent 2010; 21(3): 66-71.
[PMID: 21207916]
Somasundaram P, Vimala N, Mandke LG. Protective potential of casein phosphopeptide amorphous calcium phosphate containing paste on enamel surfaces. J Conserv Dent 2013; 16(2): 152-6.
[] [PMID: 23716969]
Lauten JD, Boyd L, Hanson MB, Lillie D, Gullion C, Madden TE. A clinical study: Melaleuca, manuka, calendula and green tea mouth rinse. Phytother Res 2005; 19(11): 951-7.
[] [PMID: 16317652]
de Rysky S. The effects of officinal herbs on inflammation of the gingival margin: A clinical trial with a newly formulated toothpaste. J Clin Dent 1988; 1(Suppl. A): A22-4.
[PMID: 3076780]
Schauenberg P, Paris F. Guide to medicinal plants. 3rd ed. London, Lutterworth Press 1977.
Mullally BH, James JA, Coulter WA, Linden GJ. The efficacy of an herbal-based toothpaste on the control of plaque and gingivitis. J Clin Periodontol 1995; 22(9): 686-9.
[] [PMID: 7593698]
Buggapati L. Herbs in dentistry. Int J Pharma Sci Inven 2016; 5(6): 07-12.
Davis CP. Normal Flora Med Microbiol. 4th ed. Galveston, TX: University of Texas Medical Branch at Galveston 1996.

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