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Current Medicinal Chemistry


ISSN (Print): 0929-8673
ISSN (Online): 1875-533X

Review Article

Tear Film, Conjunctival and Corneal Modifications Induced by Glaucoma Treatment

Author(s): Gloria Roberti, Lucia Tanga, Gianluca Manni, Ivano Riva, Alice Chandra Verticchio, Francesca Berardo, Carmela Carnevale and Francesco Oddone*

Volume 26 , Issue 22 , 2019

Page: [4253 - 4261] Pages: 9

DOI: 10.2174/0929867326666190517111823

Price: $65


Ocular surface disease is characterized by tear film instability and histopathologic and clinical changes of the ocular surface. Glaucoma patients often suffer from ocular surface disease caused by the chronic use of preserved medical treatment to reduce intraocular pressure. Benzalkonium chloride is the preservative most frequently used in glaucoma medications. Its effect on tear film, conjunctiva and cornea and the consequences in glaucoma management are discussed in this mini-review.

Keywords: Glaucoma, preservative, benzalkonium chloride, ocular surface disease, corneal modification, tear film.

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