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Current Medicinal Chemistry

Editor-in-Chief

ISSN (Print): 0929-8673
ISSN (Online): 1875-533X

Polymer-Supported Metal-Phosphine Complexes for use as Catalysts or Linkers in Medicinally-Oriented Organic Synthesis

Author(s): Nicholas E. Leadbeater

Volume 9 , Issue 23 , 2002

Page: [2147 - 2171] Pages: 25

DOI: 10.2174/0929867023368700

Price: $65

Abstract

Polymer-supported catalysts and reagents have found many uses in synthetic organic chemistry. This review discusses the preparation of polymer-supported phosphine ligands and organometallic complexes formed using these and highlights their use in reactions that are of particular interest to medicinal chemists. The scope of the review is limited to phosphine ligands and their metal complexes attached to derivitised polystyrene supports.

Keywords: polystyrene, polymer-supported catalysts, metal-phosphine complexes, organometallic catalysis, supported peptides, combinatorial catalysis


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