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Current Medicinal Chemistry

Editor-in-Chief

ISSN (Print): 0929-8673
ISSN (Online): 1875-533X

Chemogenomics: Bridging a Drug Discovery Gap

Author(s): Konrad H. Bleicher

Volume 9 , Issue 23 , 2002

Page: [2077 - 2084] Pages: 8

DOI: 10.2174/0929867023368728

Price: $65

Abstract

With the successful completion of the human genome sequencing and the resulting plethora of genetic information now available novel technologies and applications have to be established to translate the huge amount of data generated into successful biological and biomedical research programs. The integration of various drug discovery disciplines within the parallel quest for novel targets and new molecular entities has meanwhile given rise to a quite popular term in pharmaceutical research named “chemogenomics”. This review article gives an overview of the disciplines involved in this field and discusses the possible implications of this novel paradigm in drug discovery for the near future.

Keywords: target identification, target validation, library design, virtual screening, chemogenomics


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