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Current Pharmaceutical Design

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ISSN (Print): 1381-6128
ISSN (Online): 1873-4286

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Review Article

Laponite-based Nanomaterials for Biomedical Applications: A Review

Author(s): Sabya S. Das, Neelam, Kashif Hussain, Sima Singh*, Afzal Hussain, Abdul Faruk and Mike Tebyetekerwa

Volume 25, Issue 4, 2019

Page: [424 - 443] Pages: 20

DOI: 10.2174/1381612825666190402165845

Price: $65

Abstract

Laponite based nanomaterials (LBNMs) are highly diverse regarding their mechanical, chemical, and structural properties, coupled with shape, size, mass, biodegradability and biocompatibility. These ubiquitous properties of LBNMs make them appropriate materials for extensive applications. These have enormous potential for effective and targeted drug delivery comprised of numerous biodegradable materials which results in enhanced bioavailability. Moreover, the clay material has been explored in tissue engineering and bioimaging for the diagnosis and treatment of various diseases. The material has been profoundly explored for minimized toxicity of nanomedicines. The present review compiled relevant and informative data to focus on the interactions of laponite nanoparticles and application in drug delivery, tissue engineering, imaging, cell adhesion and proliferation, and in biosensors. Eventually, concise conclusions are drawn concerning biomedical applications and identification of new promising research directions.

Keywords: Laponite (LAP), laponite-based nano-materials (LBNMs), applications, composition and characteristics, drug delivery and biosensor.

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