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Current Bioactive Compounds


ISSN (Print): 1573-4072
ISSN (Online): 1875-6646

Review Article

Antipyretic Plants: An Updated Review

Author(s): Vandana Garg and Rohit Dutt*

Volume 16 , Issue 1 , 2020

Page: [4 - 12] Pages: 9

DOI: 10.2174/1573407215666190401151844

Price: $65


Background: Fever, is known as pyrexia, may occur due to infection, inflammation, or any tissue damage and disease states. Normally, the infected or damaged tissue initiates the enhanced formation of pro-inflammatory mediators like cytokines which further increases the synthesis of prostaglandin E2 (PgE2) near the hypothalamic area and thereby trigger the hypothalamus to elevate the body temperature.

Objective: Antipyretics are the agents which reduce the elevated body temperature. The most commonly used antipyretic agent, paracetamol, may be fatal due to its side effects.

Methods: In this review paper, Chemical Abstracts, Google Scholar, PubMed, and Science Direct were the sources for the published article to collect information regarding antipyretic activity.

Results: This review compiles the antipyretic plants that may be useful to treat fever due to various diseases.

Conclusion: These medicinal plants could be good alternatives for traditional allopathic antipyretics.

Keywords: Fever, pyrexia, antipyretic plants, NSAIDS, antibiotics, flavivirus.

Graphical Abstract
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