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Current Medicinal Chemistry

Editor-in-Chief

ISSN (Print): 0929-8673
ISSN (Online): 1875-533X

Review Article

Synthesis, Biological Activity and Medicinal Applications of Ruthenium Complexes Containing Carbohydrate Ligands

Author(s): Ana Cristina Fernandes*

Volume 26 , Issue 35 , 2019

Page: [6412 - 6437] Pages: 26

DOI: 10.2174/0929867326666190124124350

Price: $65

Abstract

The search for new metal-efficient drugs has attracted considerable attention of the scientific community. Among them, ruthenium complexes have emerged as an excellent alternative of platinum complexes. This review presents a thorough and timely coverage of the synthesis, biological activity and medicinal applications of ruthenium complexes bearing carbohydrate ligands, allowing a large community of readers, in particularly the community that works in organic, inorganic, bioorganometallic and medicinal chemistry, ready access to the most relevant examples.

Keywords: Ruthenium, carbohydrates, nucleolipidic complexes, polypyridyl complexes, arene complexes, cyclopentadienyl complexes, tricarbonyl complexes.

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