Green Procedure for One-Pot Synthesis of Azelaic Acid Derivatives Using Metal Catalysis

Title:Green Procedure for One-Pot Synthesis of Azelaic Acid Derivatives Using Metal Catalysis

Volume: 11 Issue: 3

Author(s): Amelita Grazia Laurenza, Michele Casiello, Marco Anzivino, Daniela Caputo, Lucia Catucci, Maria Michela Dell'Anna, Caterina Fusco, Vito Rizzi, Vincenzo Pantone, Lucia D’Accolti*Angelo Nacci

Affiliation:

• Chemistry Department, University of Bari "Aldo Moro" via Orabona 4, Bari,Italy

Keywords: Removable resource, rare earth, molybdenum complex, sustainability, azelaic acid, green chemistry.

Abstract: Background & Objective: A green one-pot synthesis of oleic acid (1) derivatives is promoted by Rare Earth Metal (REM) triflates and commercial Molybdenum dioxo dichloride (MoCl2O2) in the presence hydrogen peroxide as a green oxidant.

Results: The protocol permits to govern the oxidation selectivity by simply choosing the proper combination of Mo and Sc catalysts.

Conclusion: Methyl oleate epoxide 2a and azelaic acid 6 thus obtained are valuable industrial intermediates for synthesizing bio-compostable plastics, plasticizers of PVC, lubricating oils, cosmetics and pharmaceuticals (bactericides, anti-inflammatories, etc.).

Cite this article as:

Laurenza Grazia Amelita , Casiello Michele , Anzivino Marco , Caputo Daniela , Catucci Lucia , Dell'Anna Michela Maria , Fusco Caterina , Rizzi Vito , Pantone Vincenzo , D’Accolti Lucia *, Nacci Angelo , Green Procedure for One-Pot Synthesis of Azelaic Acid Derivatives Using Metal Catalysis, Recent Innovations in Chemical Engineering 2018; 11 (3) . https://dx.doi.org/10.2174/2405520411666181102162637