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Current Drug Safety


ISSN (Print): 1574-8863
ISSN (Online): 2212-3911

Research Article

Comparison of the Effects of Metoprolol and Bisoprolol on Lipid and Glucose Profiles in Cardiovascular Patients

Author(s): Ahmad Abdulrahman Almeman*, Yasir Ahmed Beshir and Ahmad Hamad Aldosary

Volume 14, Issue 1, 2019

Page: [27 - 30] Pages: 4

DOI: 10.2174/1574886313666181029101247

open access plus


Background: Cardioselective beta-blockers may affect glucose or lipid profiles.

Objective: We sought to compare the effects of two beta-blockers, metoprolol and bisoprolol, as the most commonly used drugs in cardiology, on glucose and lipid profiles in patients with cardiovascular diseases.

Methods: We conducted a retrospective cross-sectional matched study at Prince Sultan Cardiac Center in Burydah in August 2017. Patient records were screened, and adult patients with cardiovascular disorders who were treated with a stable dose of metoprolol or bisoprolol were included. Parameters related to glucose and lipid metabolism were compared using the Student’s t-test between the two groups.

Results and Conclusion: The metoprolol and bisoprolol arms included 204 and 200 patients, respectively.

Keywords: Metoprolol, bisoprolol, triglycerides, glucose, lipid, triglyceride.

Graphical Abstract
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