Generic placeholder image

Letters in Organic Chemistry

Editor-in-Chief

ISSN (Print): 1570-1786
ISSN (Online): 1875-6255

Research Article

Ionic Liquid Assisted Synthesis of Some 2-Aminobenzenethiols

Author(s): Dinesh K. Jangid, Keshav L. Ameta*, Surbhi Dhadda, Anjali Guleria, Prakash G. Goswami and Chandra L. Khandelwal

Volume 16, Issue 7, 2019

Page: [550 - 555] Pages: 6

DOI: 10.2174/1570178615666181011114454

Price: $65

Abstract

Ionic Liquid assisted efficient synthesis of some 2-aminobenzenethiols has been reported using three different Ionic Liquids (ILs) namely methylimidazolium tetrafluoroborate [MIM]+[BF4]−, methylimidazolium chloride [MIM]+[Cl]− and methylimidazolium nitrate [MIM]+[NO3]−. A comparative study has been carried out for the synthesis of target molecules in the presence and absence of IL, leading to conclusion that maximum yield has been observed with [MIM]+[BF4]−.

Keywords: 2-Aminobenzenethiols, 2-aminobenzothiazole, ionic liquids, environmentally benign, anions, antioxidate.

Graphical Abstract
[1]
Paronikyan, E.G.; Dashyan, S.S.; Noravyan, A.S.; Dzhagatspanyan, I.A.; Paronikyan, R.G.; Nazaryan, I.M.; Akopyan, A.G. Russ. J. Bioorganic Chem., 2015, 41, 663-669.
[2]
Muhammad, Z.A.; Masaret, G.S.; Amin, M.M.; Abdallah, M.A.; Farghaly, T.A. Med. Chem., 2017, 13, 226-238.
[3]
Ahmad, M.; Siddiqui, H.L. Zia-ur-Rehman, M.; Parvez, M. Eur. J. Med. Chem., 2010, 45, 698-704.
[4]
Pluta, K.; Morak-Młodawska, B.; Jelen, M. Eur. J. Med. Chem., 2011, 46, 3179-3189.
[5]
Shahwar, D.; Sana, U.; Ahmad, N. Turk. J. Chem., 2013, 37, 262-270.
[6]
Bondock, S.; Khalifa, W.; Fadda, A.A. Eur. J. Med. Chem., 2011, 46, 2555-2561.
[7]
Abuhaie, C.M.; Bicu, E.; Rigo, B.; Gautret, P.; Belei, D.; Farce, A.; Dubois, J.; Ghinet, A. Bioorg. Med. Chem. Lett., 2013, 23, 147-152.
[8]
Zong, D.; Zielinska-Chomej, K.; Juntti, T.; Mork, B.; Lewensohn, R.; Haag, P.; Viktorsson, K. Cell Death Dis., 2014, 5, 1111.
[9]
Zumla, A.I.; Gillespie, S.H.; Hoelscher, M.; Philips, P.P.J.; Cole, S.T.; Abubakar, I.; McHugh, T.D.; Schito, M.; Maeurer, M.; Nunn, A.J. Lancet Infect. Dis., 2014, 14, 327-340.
[10]
Zieba, A.; Latocha, M.; Sochanik, A. Med. Chem. Res., 2013, 22, 4158-4163.
[11]
Ukrainets, I.V.; Petrushova, L.A.; Dzyubenko, S.P.; Yangyang, L. Chem. Heterocycl. Compd., 2014, 50, 1047-1052.
[12]
Anastas, P.T.; Warner, J.C. Green Chemistry, Theory and Practice; Oxford University Press: New York, 1998.
[13]
Herz, R. Condensation products from reaction products of sulphur dichloride and primary arylamines, U.S. Patent 1,699,432, Jan. 16, 1928. Chem. Abstr, 1929, 23, 1140.
[14]
Gupta, R.R.; Kumar, R. Heterocycles, 1980, 14, 1145-1149.
[15]
Gupta, R.R.; Ojha, K.G.; Kumar, M. J. Heterocycl. Chem., 1980, 17, 1325-1327.
[16]
Gupta, R.R.; Gautam, R.K.; Kumar, R. Heterocycles, 1984, 22, 1143-1146.
[17]
Gupta, R.R.; Kumar, R. Synth. Commun., 1987, 17, 229-240.
[18]
Xiao, M.L.; Chen, F.H.; Chen, Z.J.; Guo, B.S.; Lv, X.H.; Tang, W.M. Chin. Chem. Lett., 2007, 18, 258-260.
[19]
Dzyuba, S.V.; Kollar, K.D.; Sabnis, S.S. J. Chem. Educ., 2009, 86, 856-858.
[20]
Jain, R.; Sharma, K.; Kumar, D. Helv. Chim. Acta, 2013, 96, 414-418.

Rights & Permissions Print Cite
© 2024 Bentham Science Publishers | Privacy Policy