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Current Medicinal Chemistry

Editor-in-Chief

ISSN (Print): 0929-8673
ISSN (Online): 1875-533X

Comparative Evaluation of L-Fd4C and Related Nucleoside Analogs as Promising Antiviral Agents

Author(s): Shu-Hui Chen

Volume 9 , Issue 9 , 2002

Page: [899 - 912] Pages: 14

DOI: 10.2174/0929867024606696

Price: $65

Abstract

As documented in the recent literature, there are more than 50 million people infected with HIV worldwide to date since the emergence of HIV and AIDS in the Western world in 1981. More importantly, about 7000 people die of AIDS daily with 2.5 and 2.6 millions total deaths in 1998 and 1999, respectively. On the other hand, human hepatitis B virus (HBV) is the leading cause of chronic hepatitis in the world. According to

Keywords: antiviral agents, nucleosides, anti-hbv agents, oxetanocins, acyclic nucleosides, oxetanocin, cyclobut, acyclovir


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