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Letters in Organic Chemistry


ISSN (Print): 1570-1786
ISSN (Online): 1875-6255

Research Article

Synthesis of Substituted Phenols via Hydroxylation of Arenes Using Hydrogen Peroxide in the Presence of Hexaphenyloxodiphosphonium Triflate

Author(s): Mohammad Mehdi Khodaei*, Abdolhamid Alizadeh* and Hadis Afshar Hezarkhani

Volume 15 , Issue 10 , 2018

Page: [878 - 882] Pages: 5

DOI: 10.2174/1570178615666180430121524

Price: $65


A mild and efficient protocol for the synthesis of phenols from arenes has been developed using aqueous hydrogen peroxide as an oxidizing agent and hexaphenyloxodiphosphonium triflate as a promoter. The reactions were carried out with the simple procedure in EtOH-H2O at room temperature in short reaction times.

Keywords: Substituted phenols, hexaphenyloxodiphosphonium triflate, hydroxylation, hydrogen peroxide, arene.

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