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Letters in Organic Chemistry


ISSN (Print): 1570-1786
ISSN (Online): 1875-6255

Review Article

Biological Importance of Phenol Derivatives as Potent Bioactive Compound: A Review

Author(s): Arvind Kumar* and Arun K. Mishra

Volume 15, Issue 4, 2018

Page: [251 - 264] Pages: 14

DOI: 10.2174/1570178614666171130155539

Price: $65


Introduction: Phenol or carbolic acid is an aromatic compound and has mild acidic nature. In 1834, it was firstly achieved by Friedlieb Ferdinand by the destructive extraction of coal tar. It is used as a significant raw material in quite a lot of chemical manufacturing. Phenol derivatives have been found to possess Antimicrobial, Analgesic, Anti-inflammatory, Antioxidant, Anti-convulsant, Anti-cancer, Anesthetic, Antiseptic and Disinfecticides, Anti-tubercular and Anti-parkinson activity. Several more compounds have been discovered and many are still being focused.

Conclusion: The main objective of this article is to show up the different derivatives and the pharmacological activities of Phenol and its derivatives. It can be concluded that Phenol and its derivatives posses significant therapeutic functions and many potent derivatives are still to be discovered.

Keywords: Analgesic activity, anti-cancer activity, anti-convulsant activity, anti-inflammatory activity, anti-microbial activity, anti-oxidant activity, anti-tubercular activity, phenol.

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