Abstract
Identification of transformation products and elucidation of degradation pathways of pharmaceuticals in the environment is a challenging task due to the numerous compounds, their low concentrations, and complexity of the environmental matrices. This manuscript summarizes present knowledge about main degradation routes of pharmaceuticals in the environment and review published methods and approaches for their determination in environmental samples, with a special emphasis on the mass spectrometry and nuclear magnetic resonance techniques.
Keywords: Pharmaceuticals, environment, fate, degradation path, liquid chromatography, mass spectrometry, nuclear magnetic resonance.
Current Organic Chemistry
Title:Transformation Products of Pharmaceuticals in the Environment: Formation and Analysis
Volume: 22 Issue: 10
Author(s): Sandra Babic*, Martina Biosic and Irena Skoric
Affiliation:
- Department of Analytical Chemistry, Faculty of Chemical Engineering and Technology, University of Zagreb, Marulicev trg 19, Zagreb,Croatia
Keywords: Pharmaceuticals, environment, fate, degradation path, liquid chromatography, mass spectrometry, nuclear magnetic resonance.
Abstract: Identification of transformation products and elucidation of degradation pathways of pharmaceuticals in the environment is a challenging task due to the numerous compounds, their low concentrations, and complexity of the environmental matrices. This manuscript summarizes present knowledge about main degradation routes of pharmaceuticals in the environment and review published methods and approaches for their determination in environmental samples, with a special emphasis on the mass spectrometry and nuclear magnetic resonance techniques.
Export Options
About this article
Cite this article as:
Babic Sandra *, Biosic Martina and Skoric Irena , Transformation Products of Pharmaceuticals in the Environment: Formation and Analysis, Current Organic Chemistry 2018; 22 (10) . https://dx.doi.org/10.2174/1385272822666171122160926
DOI https://dx.doi.org/10.2174/1385272822666171122160926 |
Print ISSN 1385-2728 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5348 |
Call for Papers in Thematic Issues
Advances of Heterocyclic Chemistry with Pesticide Activity
Global food safety and security will continue to be a global concern for the next 50 years and beyond. Plant diseases have had a significant impact on food safety and security throughout the entire food chain, from primary production to consumption. While conventional chemical pesticides have been traditionally used for ...read more
Calculation design of covalent/metal organic framework based catalysts
This research area combines theoretical computation and screening with machine learning for the design of covalent/metal organic framework-based catalysts, bridging the disciplines of organic chemistry, physical chemistry, computational chemistry, materials science, and machine learning. It covers several critical aspects: designing and synthesizing organic catalysts for improved performance, applying computational methods ...read more
Carbohydrates conversion in biofuels and bioproducts
Biomass pretreatment, hydrolysis, and saccharification of carbohydrates, and sugars bioconversion in biofuels and bioproducts within a biorefinery framework. Carbohydrates derived from woody biomass, agricultural wastes, algae, sewage sludge, or any other lignocellulosic feedstock are included in this issue. Simulation, techno-economic analysis, and life cycle analysis of a biorefinery process are ...read more
Catalytic C-H bond activation as a tool for functionalization of heterocycles
The major topic is the functionalization of heterocycles through catalyzed C-H bond activation. The strategies based on C-H activation not only provide straightforward formation of C-C or C-X bonds but, more importantly, allow for the avoidance of pre-functionalization of one or two of the cross-coupling partners. The beneficial impact of ...read more
Related Journals
- Author Guidelines
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers
- Announcements
Related Articles
-
Double-Edged Effects of Arsenic Compounds: Anticancer and Carcinogenic Effects
Current Drug Metabolism Hypoxia, Lead Toxicities and Oxidative Stress: Cell Signaling, Molecular Interactions and Antioxidant (Vitamin C) Defense
Current Signal Transduction Therapy Molecular Mechanisms of Renal Blood Flow Autoregulation
Current Vascular Pharmacology Lung Cancer Stem Cells as a Target for Therapy
Anti-Cancer Agents in Medicinal Chemistry Monoamine Oxidase Inhibitors as Neuroprotective Agents in Age-Dependent Neurodegenerative Disorders
Current Pharmaceutical Design Future Management of Chronic Myeloid Leukemia: From Dose Optimization to New Agents
Current Cancer Drug Targets Purine Analogues as Kinase Inhibitors: A Review
Recent Patents on Anti-Cancer Drug Discovery HtrA Protease Family as Therapeutic Targets
Current Pharmaceutical Design Histone Deacetylase Inhibitors Target Diabetes via Chromatin Remodeling or as Chemical Chaperones?
Current Diabetes Reviews Patent Selections:
Recent Patents on Anti-Infective Drug Discovery Role of Thyroid Hormones in Insulin Resistance and Diabetes
Immunology, Endocrine & Metabolic Agents in Medicinal Chemistry (Discontinued) New Cell Therapy Using Bone Marrow-Derived Stem Cells/Endothelial Progenitor Cells to Accelerate Neovascularization in Healing of Experimental Ulcerative Colitis
Current Pharmaceutical Design Central Oxytocinergic Neurotransmission: A Drug Target for the Therapy of Psychogenic Erectile Dysfunction
Current Drug Targets Mixed Connective Tissue Disease (MCTD) – A Coming of Age
Current Rheumatology Reviews Structure and Function of Complement Activating Enzyme Complexes C1 and MBL-MASPs
Current Protein & Peptide Science Editorial: (Thematic Issue: Novel Strategies for Cardiac Repair Post-Myocardial Infarction)
Current Pharmaceutical Design Cabazitaxel: A Novel Drug for Hormone-Refractory Prostate Cancer
Mini-Reviews in Medicinal Chemistry The Association between Metabolic Syndrome and Serum Levels of Adiponectin and High Sensitive C Reactive Protein in Gorgan
Endocrine, Metabolic & Immune Disorders - Drug Targets An Overview of 7α- and 7β-Hydroxysteroid Dehydrogenases: Structure, Specificity and Practical Application
Protein & Peptide Letters Serotonergic Integration In the Intestinal Mucosa
Current Pharmaceutical Design