Background: Microwave irradiation usage has reduced the time of reactions in organic synthesis. Nano-Fe2O3 proved to be a highly efficient and recyclable catalyst for the synthesis of organic molecules.
Objective: One pot synthesis of substituted oxadiazoles using ultrasonic irradiation and nano- Fe2O3 as catalyst at ambient conditions.
Method: Probe sonicator was used for ultrasonication synthesis along with nano- Fe2O3 as catalyst.
Results: The synthesised substituted oxadiazoles were obtained in high yields and shorter reaction time.
Conclusion: Eco-friendly protocols, easy recovery of catalyst, efficient recyclability, high stability of catalyst, high yields and lesser reaction time render the protocol sustainable and economic.