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Current Medicinal Chemistry

Editor-in-Chief

ISSN (Print): 0929-8673
ISSN (Online): 1875-533X

Gene Regulation in Cancer Gene Therapy Strategies

Author(s): Ian Scanlon, Panos Lehouritis, Ion Niculescu-Duvaz, Richard Marais and Caroline J. Springer

Volume 10, Issue 20, 2003

Page: [2175 - 2184] Pages: 10

DOI: 10.2174/0929867033456837

Price: $65

Abstract

Regulation of expression in gene therapy is considered to be a very desirable goal, preventing toxic effects and improving biological efficacy. A variety of systems have been reported in an ever widening range of applications, this paper describes these systems with specific reference to cancer gene therapy.

Keywords: transcriptional control, regulated expression, gdept, suicide gene


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