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Current Medical Imaging

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ISSN (Print): 1573-4056
ISSN (Online): 1875-6603

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General Research Article

Justification of Increasing the Blood Flow Velocity in the Arteries of the Thyroid Gland in Autoimmune Thyroiditis as a Reflection of Endothelial Changes Due to Inflammatory Status

Author(s): Nataliia I. Chekalina*, Yurii H. Burmak, Yeuhen Ye. Petrov, Zinaiida O. Borysova, Tetiana A. Trybrat, Svitlana V. Shut and Yurii M. Kazakov

Volume 15, Issue 1, 2019

Page: [61 - 65] Pages: 5

DOI: 10.2174/1573405613666170921165445

Price: $65

Abstract

Objective: The aim of the research was to determine the dependence of the blood flow velocity in the thyroid arteries in patients with Autoimmune Thyroiditis (AIT) on the presence of atherosclerotic carotid disease and the level of systemic blood pressure.

Methods: The research involved 20 patients with AIT in euthyroid state, 30 patients AIT in euthyroid state with stable Coronary Heart Disease (CHD), 30 patients with stable CHD and 30 healthy individuals. Participants of the research were examined using ultrasound of carotid arteries and inferior thyroid arteries. Parameters of blood flow velocity were compared with the level of systemic blood pressure.

Results: In AIT peak systolic velocity and resistance index in the inferior thyroid arteries were significantly higher than in healthy individuals and patients with CHD (p<0.05). In patients with CHD velocity parameters in carotid arteries were high, unlike in the healthy individuals and patients with AIT (p<0.05). In patients with AIT without CHD the atherosclerotic changes of carotid arteries were not found. Increased systemic blood pressure was noticed in all patients with CHD without significant differences between groups.

Conclusion: The value of peak systolic velocity and resistance index of inferior thyroid arteries in autoimmune thyroiditis are noticed even with euthyroidism and do not depend on systemic blood pressure and atherosclerosis of carotid arteries. Increasing the thyroid arterial blood flow velocity parameters should be considered as sign of an active inflammatory period AIT, where advanced fibrosis is not present.

Keywords: Autoimmune thyroiditis, atherosclerosis, carotid arteries, thyroid arteries, systemic blood pressure, blood flow velocity.

Graphical Abstract

[1]
Vanderpump MPJ. The epidemiology of thyroid disease. Br Med Bull 2011; 99(1): 39-51.
[2]
Karachentsov YU. Fourteenth Danilevsky reading. Chotirnadtsyat Danilevsk chitannya. In: Proceedings of the conference with international participation: Achievements and prospects of experimental and clinical Endocrinology. Kharkiv, 2015: pp. 104- 72
[3]
Weetman A. Chronic autoimmune thyroiditis The Thyroid a Fundamental and Clinical Text eds LE Braverman & RD Utiger New York: Lippincot Williams 2005 .
[4]
Vitti P, Rago T, Mazzeo S, et al. Thyroid blood flow evaluation by color-flow Doppler sonography distinguishes Graves’ disease from Hashimoto’s thyroiditis. J Endocrinol Invest 1995; 18(11): 857-61.
[5]
Pearce SH, Brabant G, Duntas LH, et al. 2013 ETA Guideline: Management of subclinical Hypothyroidism; European thyroid association. Eur Thyroid J 2013; 2(4): 215-28.
[6]
Montalescot G, Sechtem U, Achenbach S, et al. 2013 ESC guidelines on the management of stable coronary artery disease. Eur Heart J 2013; 34: 2949-3003.
[7]
Mancia G, Fagard R, Narkiewicz K, et al. 2013 ESH/ESC Guidelines for the management of arterial hypertension. J Hypertens 2013; 31: 1281-357.
[8]
Stein J, Korcarz C, Hurst T, et al. Use of carotid ultrasound to identify subclinical vascular disease and evaluate cardiovascular disease risk: A consensus statement from the American society of echocardiography carotid intima-media thickness task force endorsed by the society of vascular medicine. J Am Society Echoc 2008; 21(2): 93-111.
[9]
Von Reutern GM, Goertler MW, Bornstein NM, et al. Grading carotid stenosis using ultrasonic methods. Stroke 2012; 43: 916-21.
[10]
Chaudhary V, Bano S. Thyroid ultrasound. Indian J Endocrinol Metab 2013; 17(2): 219-27.
[11]
Strizhakova EM, Strizhakov AA, Plyuhina EI. Ultrasonic evaluation of the blood supply of the thyroid gland in autoimmune thyroiditisUl'trazvukovaya ocenka krovosnabzheniya shchitovidnoj zhelezy pri autoimmunnom tireoidite Ul'trazvukovaya i funkcional'naya diagnostika 2008; 3: 116
[12]
Caruso G, Attard M, Caronia A, Lagalla R. Color Doppler measurement of blood flow in the inferior thyroid artery in patients with autoimmune thyroid disease. Eur J Radiol 2000; 36(6): 5-10.
[13]
Vitti P, Rago T, Mazzeo S, Brogioni S, et al. Thyroid blood flow evaluation by color-flow Doppler sonography distinguishes Graves’ disease from Hashimoto’s thyroiditis. J Endocrinol Invest 1995; 18(11): 857-61.
[14]
Bogazzi F, Bartalena L, Vitti P, Rago T, Brogioni S, Martino E. Color flow Doppler sonography in thyrotoxicosis factitia. J Endocrinol Invest 1996; 19(9): 603-6.
[15]
Bhargava A. . The utility of color-flow doppler sonography in the evaluation of hyperthyroidism. J Thyroid Disorder Therapy 2015 Available from: [cited 2017 Apr 27]. (http://dx.doi.org/10.4172/2167-7948.1000e117).
[16]
Chekalina NI, Kazakov YM, Mamontova TV, Mamontova TV, Vesnina LE, Kaidashev IP. Resveratrol more effectively than quercetin reduces endothelium degeneration and level of necrosis factor α in patients with coronary artery disease. Wiad Lek 2016; 69(3 pt 2): 475-9.
[17]
Chekalina NI. Antiinflammatory effects of resveratrol in stable coronary artery disease and concominant autoimmune thyroiditis. Cardiovasc Dis 2016; XLVII(3): 3-8.

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