Title:Synthesis of 2,4,5-Triaryl-1H-Imidazoles under Kornblum Oxidative Condition
Volume: 15
Issue: 6
Author(s): Mohammad Hosein Sayahi, Mina Bahmei, Setareh Moghimi, Mohammad Mahdavi, Loghman Firoozpour and Alireza Foroumadi*
Affiliation:
- Drug Design and Development Research Center, Tehran University of Medical Sciences, Tehran,Iran
Keywords:
Imidazoles, Kornblum oxidation, benzyl halide, one-pot, three-component reaction, MCRs.
Abstract: 2,4,5-Triaryl-1H-imidazoles were synthesized from benzyl bromides under Kornblum oxidative
condition. The reaction proceeded via an in situ oxidation followed by condensation to afford
the desired products in good yields.