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Current Psychiatry Reviews


ISSN (Print): 1573-4005
ISSN (Online): 1875-6441

Review Article

Theory of Mind in the Early Course of Schizophrenia

Author(s): Nora S. Vyas*, Yi Wang, Shemin S. Vyas, Eoin Killackey, Tor-Arne Haugland and Raymond C.K. Chan

Volume 13, Issue 2, 2017

Page: [102 - 110] Pages: 9

DOI: 10.2174/1573400513666170502125017

Price: $65


Theory of mind deficit is a core feature of schizophrenia and is considered a vulnerability marker of the disorder. The majority of studies measuring theory of mind in schizophrenia involve multiple-episode or chronic schizophrenia patients, and therefore it is important to delineate whether these deficits occur before or following illness-onset by assessing high-risk subjects (clinical high risk and ultra-high risk), early-onset psychosis, and first-degree relatives. We address the question of whether theory of mind impairment is specific or a facet of general cognitive impairment in these clinical populations, and incorporate genetic and neuroimaging studies on the theory of mind. The review provides a succinct evaluation of the literature, discusses current limitations and proposes future directions.

Keywords: Theory of mind, adolescence, neuroimaging, social cognition, unaffected relatives, high risk, endophenotype, mentalising.

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