摘要
背景:药物包埋的纳米颗粒具有作为各种疾病的有效解毒剂的效力。可以提高药物包封的纳米颗粒的生物利用度,从而与标准制剂相比,产率显着更高。在证明其具有增强的热物理性质和药物稳定性的能力之后,药物包埋的纳米颗粒的发展已经显着改善。它也被广泛地用于癌症诊断,由此可以修饰纳米颗粒的表面以使得纳米载体能够到达目标位置。因此,封装的纳米颗粒可以由于多面体性质和生物物理线索来显示神经干细胞分化以控制细胞分化。 目的:在这个概述中,药物包埋的纳米颗粒在下游应用中的不同优点以其吸引人的特征进行了叙述。 结论:药物包埋的纳米颗粒的应用是不受限制的,因为它可以根据生活系统中的特定靶细胞定制。
关键词: 封装的纳米颗粒,药物负载,纳米载体,生物医学,靶向递送,受体。
Current Medicinal Chemistry
Title:Drug Encapsulated Nanoparticles for Treating Targeted Cells
Volume: 24 Issue: 30
关键词: 封装的纳米颗粒,药物负载,纳米载体,生物医学,靶向递送,受体。
摘要: Background: Drug encapsulated nanoparticle has the potency to act as an effective antidote for various diseases. It is possible to enhance the bioavailability of drug encapsulated nanoparticle, whereby the yield is significantly higher compared to the standard formulation. The development with drug encapsulated nanoparticle has been improved drastically after demonstrating its capability of showing the enhanced thermophysical properties and stability of the drug. It is also utilized widely in cancer diagnoses, whereby the surface of the nanoparticle can be modified to enable the nanocarriers to reach the targeted location. Thus, the encapsulated nanoparticle can reveal neural stem cell differentiation due to the multifaceted nature and the biophysical cues to control the cell differentiation.
Objective: In this overview, different advantages of the drug encapsulated nanoparticle for the downstream applications are narrated with its appealing characteristics.
Conclusion: The application of the drug encapsulated nanoparticle is unrestricted as it can be customized to the specific target cell in the living system.
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Cite this article as:
Drug Encapsulated Nanoparticles for Treating Targeted Cells, Current Medicinal Chemistry 2017; 24 (30) . https://dx.doi.org/10.2174/0929867324666170502122444
DOI https://dx.doi.org/10.2174/0929867324666170502122444 |
Print ISSN 0929-8673 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-533X |
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