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Current Medicinal Chemistry


ISSN (Print): 0929-8673
ISSN (Online): 1875-533X

Review Article

Cu2+ Biological Imaging Probes Based on Different Sensing Mechanisms

Author(s): Caixia Yin*, Jiawei Li and Fangjun Huo

Volume 26 , Issue 21 , 2019

Page: [3958 - 4002] Pages: 45

DOI: 10.2174/0929867324666170428110724

Price: $65


In recent years, fluorescent probes have recently attracted attention from researchers. As a vital trace metal element, Cu2+ has an important role in the human body and environment. Therefore, the development and design of Cu2+ small-molecular fluorescent probes has been an active research area. This review focuses on the developments in the area of small-molecular fluorescent probes for Cu2+ in biological applications according to different sensing mechanisms including charge transfer (CT), electron transfer, energy transfer, excited-state intramolecular proton transfer (ESIPT).

Keywords: Detection, Metal ions, Cu2+ small-molecular fluorescent probes, Biological applications, Sensing mechanisms, charge transfer (CT).

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