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Current Drug Metabolism


ISSN (Print): 1389-2002
ISSN (Online): 1875-5453

Review Article

Methods of Screening-Purification and Antimicrobial Potentialities of Bacteriocin in Health Care

Author(s): Varish Ahmad, Qazi Mohammad Sajid Jamal, Mughees Uddin Siddiqui, Arun K. Shukla, Mohammad A. Alzohairy, Mohammad A. Al Karaawi and Mohammad Amjad Kamal*

Volume 18, Issue 9, 2017

Page: [814 - 830] Pages: 17

DOI: 10.2174/1389200218666170116111309

Price: $65


Background: Bacteriocin have been tested as safe and effective alternative molecules over the currently used chemotherapeutic agents. Thus, being an important clinical significance, its screening and recovery methods along with its application are poorly described. Therefore, their screening, purification strategies and utilities must me extended. Thus, in this review, we, summarize potential application, various screening and purification methods used for recovery of bacteriocins.

Methods: To complete this review, many reviews and previously published reports were studied. We, concentrated on review question and exclusion and inclusion criteria. The quality of content was evaluated by the quality the quality contents evaluation method. The standard method is used to describe the useful contents of available resources and appraised.

Results: One hundred twenty research and review reports were used to complete this report. Sixty reports were used to make a collective information on screening and production of Bacteriocin Eighty two papers were used to explore the antimicrobial, therapeutic, diagnostic etc potentialities of bacteriocin in diverse field. The summarize form of data also presented in the form of tables and figures. This review describes the various methods and parameters that must be considered during the screening and purification methods. Moreover, the useful information is collected in regard represent it therapeutic potentialities in various fields for the welfare of human being.

Conclusions: The conclusion of this review presented the significance of a fundamental framework for planning to understanding the basic requirement needed for fast, cost effective screening and purification of bacteriocins. The summered area of their utilities also helpful to extend the research field of bacteriocin. Thus, this report would be useful not only to scale up the screening and production strategies faster at economical rate, but also provides a platform to extend the research field of bacteriocin in many ways.

Keywords: Bacteriocin, screening, purification, antimicrobial, therapeutics potentialities, health care.

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