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CNS & Neurological Disorders - Drug Targets

Editor-in-Chief

ISSN (Print): 1871-5273
ISSN (Online): 1996-3181

Review Article

Brain Tumor Segmentation Using Deep Belief Networks and Pathological Knowledge

Author(s): Tianming Zhan, Yi Chen, Xunning Hong, Zhenyu Lu and Yunjie Chen

Volume 16, Issue 2, 2017

Page: [129 - 136] Pages: 8

DOI: 10.2174/1871527316666170113101559

Price: $65

Abstract

In this paper, we propose an automatic brain tumor segmentation method based on Deep Belief Networks (DBNs) and pathological knowledge. The proposed method is targeted against gliomas (both low and high grade) obtained in multi-sequence magnetic resonance images (MRIs). Firstly, a novel deep architecture is proposed to combine the multi-sequences intensities feature extraction with classification to get the classification probabilities of each voxel. Then, graph cut based optimization is executed on the classification probabilities to strengthen the spatial relationships of voxels. At last, pathological knowledge of gliomas is applied to remove some false positives. Our method was validated in the Brain Tumor Segmentation Challenge 2012 and 2013 databases (BRATS 2012, 2013). The performance of segmentation results demonstrates our proposal providing a competitive solution with stateof- the-art methods.

Keywords: Brain tumor segmentation, deep belief networks, graph cut, pathological knowledge.

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