Abstract
Non-Melanoma Skin Cancer (NMSC) is the most common form of skin cancer. Common risk factors linked to the occurrence of NMSC are occupational exposure to chemicals, ultraviolet light exposure, immunosuppresion, human papillomavirus infection, artificial tanning, premalignant skin lesions and inherited skin conditions. The various clinical manifestations of NMSC depend on location and subtype. Management of NMSC includes pathology confirmation, staging and treatment. Retinoid and nicotinamide have been shown to be effective for the prevention of NMSC, primary treatments available for the treatment of NMSC are wide local excision, Mohs micrographic surgery (MMS), radiotherapy (RT), topical agents (5FU cream) and photodynamic therapy (PDT).
The choice of definite treatment depends on many factors such as performance status and age of the patient, location and size of the tumor, etc.Keywords: Non-melanoma skin cancer, MMS, PDT, BCC, SCC.
Current Cancer Therapy Reviews
Title:Non-Melanoma Skin Cancer – Overview
Volume: 12 Issue: 3
Author(s): Kurian Joseph
Affiliation:
Keywords: Non-melanoma skin cancer, MMS, PDT, BCC, SCC.
Abstract: Non-Melanoma Skin Cancer (NMSC) is the most common form of skin cancer. Common risk factors linked to the occurrence of NMSC are occupational exposure to chemicals, ultraviolet light exposure, immunosuppresion, human papillomavirus infection, artificial tanning, premalignant skin lesions and inherited skin conditions. The various clinical manifestations of NMSC depend on location and subtype. Management of NMSC includes pathology confirmation, staging and treatment. Retinoid and nicotinamide have been shown to be effective for the prevention of NMSC, primary treatments available for the treatment of NMSC are wide local excision, Mohs micrographic surgery (MMS), radiotherapy (RT), topical agents (5FU cream) and photodynamic therapy (PDT).
The choice of definite treatment depends on many factors such as performance status and age of the patient, location and size of the tumor, etc.Export Options
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Cite this article as:
Joseph Kurian, Non-Melanoma Skin Cancer – Overview, Current Cancer Therapy Reviews 2016; 12 (3) . https://dx.doi.org/10.2174/1573394713666161214124214
DOI https://dx.doi.org/10.2174/1573394713666161214124214 |
Print ISSN 1573-3947 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-6301 |
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argeted Protein Degradation is gaining momentum in cancer therapy, it facilitate targeting undruggable proteins, it overcome cancer resistance and avoid undesirable side effects. Thus small molecules degraders have emerged as novel therapeutic strategy. Targeted protein degradation (TPD), the process of eliminating a protein of interest hold a great promise for ...read more
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