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Letters in Drug Design & Discovery

Editor-in-Chief

ISSN (Print): 1570-1808
ISSN (Online): 1875-628X

Research Article

Synthesis and Nematocidal Activity of Novel Pyrazole Carboxamide Derivatives Against Meloidogyne incognita

Author(s): Wen Zhao, Zhong-Hua Shen, Jia-Hua Xing, Tian-Ming Xu, Wei-Li Peng and Xing-Hai Liu

Volume 14 , Issue 3 , 2017

Page: [323 - 329] Pages: 7

DOI: 10.2174/1570180813666160930164327

Price: $65

Abstract

Background: A series of novel 2,6-dichloro-4-(trifluoromethyl)phenyl)-3-(trifluoromethyl) - 1H-pyrazole-4-carboxamide derivatives were designed and synthesized.

Method: All the title compounds were confirmed by 1H NMR and MS.

Results: The primarily nematicidal activity results indicated that some of them exhibited moderate control efficacy against the tomato root-knot nematode disease caused by Meloidogyne incognita.

Keywords: Synthesis, trifluoromethylpyrazole, nematocidal activity, Meloidogyne incognita.

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